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PROTACs: great opportunities for academia and industry
scientific article published on 24 December 2019
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28 April 2020
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title
PROTACs: great opportunities for academia and industry
(English)
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6927964
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Xiuyun Sun
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1
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28 April 2020
Hongying Gao
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2
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28 April 2020
Yiqing Yang
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3
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28 April 2020
Ming He
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28 April 2020
Yue Wu
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5
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28 April 2020
Yugang Song
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28 April 2020
Yan Tong
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28 April 2020
Yu Rao
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8
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publication date
24 December 2019
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28 April 2020
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Signal Transduction and Targeted Therapy
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28 April 2020
volume
4
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28 April 2020
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64
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28 April 2020
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23 February 2021
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Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion
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23 February 2021
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23 February 2021
Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6
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23 February 2021
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23 February 2021
Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance
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Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain
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23 February 2021
Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation
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23 February 2021
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23 February 2021
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
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23 February 2021
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23 February 2021
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23 February 2021
Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines
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23 February 2021
Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
Isolation of a gene encoding a novel member of the nuclear receptor superfamily from the critical region of Usher syndrome type IIa at 1q41
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23 February 2021
Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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23 February 2021
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Identifiers
DOI
10.1038/S41392-019-0101-6
1 reference
stated in
Europe PubMed Central
PMC publication ID
6927964
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31885879%20AND%20SRC:MED&resulttype=core&format=json
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PMC publication ID
6927964
1 reference
stated in
Europe PubMed Central
PMC publication ID
6927964
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31885879%20AND%20SRC:MED&resulttype=core&format=json
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28 April 2020
PubMed publication ID
31885879
1 reference
stated in
Europe PubMed Central
PMC publication ID
6927964
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31885879%20AND%20SRC:MED&resulttype=core&format=json
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28 April 2020
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