(Q92284312)

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28 April 2020

title

Degradation of Bruton's tyrosine kinase mutants by PROTACs for potential treatment of ibrutinib-resistant non-Hodgkin lymphomas (English)

1 reference

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28 April 2020

3

1 reference

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28 April 2020

author name string

Yonghui Sun

1

1 reference

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28 April 2020

Ning Ding

2

1 reference

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28 April 2020

Zimo Yang

4

1 reference

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28 April 2020

Wanli Liu

5

1 reference

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28 April 2020

Jun Zhu

6

1 reference

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28 April 2020

Yu Rao

7

1 reference

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28 April 2020

publication date

11 March 2019

1 reference

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28 April 2020

1 reference

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28 April 2020

volume

33

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28 April 2020

issue

8

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28 April 2020

page(s)

2105-2110

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Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001

28 April 2020

cites work

1 reference

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7 January 2021

Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: a study by the Groupe d'Etude des Lymphomes de l'Adulte

1 reference

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7 January 2021

Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era

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7 January 2021

Detection of translocation t(11;14)(q13;q32) in mantle cell lymphoma by fluorescence in situ hybridization

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7 January 2021

Mantle cell lymphoma: observation to transplantation

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7 January 2021

Improvement of Overall Survival in Advanced Stage Mantle Cell Lymphoma

1 reference

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7 January 2021

Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma

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7 January 2021

Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma.

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7 January 2021

Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma

1 reference

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7 January 2021

PROTAC-induced BTK degradation as a novel therapy for mutated BTK C481S induced ibrutinib-resistant B-cell malignancies

1 reference

https://api.crossref.org/works/10.1038%2FS41375-019-0440-X

7 January 2021

Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

1 reference

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7 January 2021

Small-Molecule PROTACS: New Approaches to Protein Degradation

1 reference

https://api.crossref.org/works/10.1038%2FS41375-019-0440-X

7 January 2021

Bruton tyrosine kinase degradation as a therapeutic strategy for cancer

1 reference

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7 January 2021

Targeting the C481S Ibrutinib-Resistance Mutation in Bruton's Tyrosine Kinase using PROTAC-mediated Degradation.

1 reference

https://api.crossref.org/works/10.1038%2FS41375-019-0440-X

7 January 2021

Delineating the role of cooperativity in the design of potent PROTACs for BTK.

1 reference

https://api.crossref.org/works/10.1038%2FS41375-019-0440-X

7 January 2021

Substitution scanning identifies a novel, catalytically active ibrutinib-resistant BTK cysteine 481 to threonine (C481T) variant.

1 reference

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7 January 2021

Ibrutinib resistance in chronic lymphocytic leukemia

1 reference

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7 January 2021

Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation

1 reference

https://api.crossref.org/works/10.1038%2FS41375-019-0440-X

7 January 2021

Functional characterization of BTK(C481S) mutation that confers ibrutinib resistance: exploration of alternative kinase inhibitors.

1 reference

https://api.crossref.org/works/10.1038%2FS41375-019-0440-X

7 January 2021

10.1038/S41375-019-0440-X

Identifiers

DOI

1 reference

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28 April 2020

1 reference