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The Polycomb complex PRC2 and its mark in life
scientific article (publication date: 20 January 2011)
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Europe PubMed Central
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3760771
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20 January 2020
review article
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title
The Polycomb complex PRC2 and its mark in life
(English)
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PubMed
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23 April 2017
stated in
Europe PubMed Central
PMC publication ID
3760771
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248841%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
main subject
polycomb repressive complex 2
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author
Raphael Margueron
series ordinal
1
1 reference
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Europe PubMed Central
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3760771
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248841%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
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Danny Reinberg
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2
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3760771
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20 January 2020
language of work or name
English
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23 April 2017
publication date
1 January 2011
1 reference
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Europe PubMed Central
PMC publication ID
3760771
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20 January 2020
published in
Nature
2 references
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PubMed
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23 April 2017
stated in
Europe PubMed Central
PMC publication ID
3760771
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248841%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
volume
469
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PubMed
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23 April 2017
stated in
Europe PubMed Central
PMC publication ID
3760771
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248841%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
issue
7330
2 references
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PubMed
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23 April 2017
stated in
Europe PubMed Central
PMC publication ID
3760771
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248841%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
page(s)
343-349
1 reference
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Europe PubMed Central
PMC publication ID
3760771
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20 January 2020
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Comprehensive evaluation of the role of EZH2 in the growth, invasion, and aggression of a panel of prostate cancer cell lines
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A region of the human HOXD cluster that confers polycomb-group responsiveness
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In vivo residue-specific histone methylation dynamics
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3 June 2018
Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice
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3 June 2018
A vertebrate Polycomb response element governs segmentation of the posterior hindbrain
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3 June 2018
Polycomb group protein enhancer of zeste 2 is an oncogene that promotes the neoplastic transformation of a benign prostatic epithelial cell line
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Diversity of Polycomb group complexes in plants: same rules, different players?
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Targeted overexpression of EZH2 in the mammary gland disrupts ductal morphogenesis and causes epithelial hyperplasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
ATXR5 and ATXR6 are H3K27 monomethyltransferases required for chromatin structure and gene silencing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Functional anatomy of polycomb and trithorax chromatin landscapes in Drosophila embryos
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
A model for transmission of the H3K27me3 epigenetic mark
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Facultative heterochromatin: is there a distinctive molecular signature?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
H3K27 demethylases, at long last
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
3 June 2018
Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
3 June 2018
The polycomb group protein Suz12 is required for embryonic stem cell differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Polycomb recruitment to DNA in vivo by the YY1 REPO domain.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
3 June 2018
Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
3 June 2018
Suz12 binds to silenced regions of the genome in a cell-type-specific manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
3 June 2018
Genome-wide analysis of Polycomb targets in Drosophila melanogaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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3 June 2018
Roles of JUMONJI in mouse embryonic development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
3 June 2018
A novel human homologue of Drosophila polycomblike gene is up-regulated in multiple cancers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
3 June 2018
EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
3 June 2018
The polycomb complex protein mes-2/E(z) promotes the transition from developmental plasticity to differentiation in C. elegans embryos.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
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26 November 2018
Polycomb proteins remain bound to chromatin and DNA during DNA replication in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
26 November 2018
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
26 November 2018
Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
26 November 2018
Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
26 November 2018
ESC, ESCL and their roles in Polycomb Group mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
26 November 2018
Recruitment of Drosophila Polycomb-group proteins by Polycomblike, a component of a novel protein complex in larvae.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
26 November 2018
Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
26 November 2018
Polycomb Group proteins: an evolutionary perspective.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
26 November 2018
Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3760771
retrieved
26 November 2018
Identifiers
DOI
10.1038/NATURE09784
3 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21248841
retrieved
23 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
211088
stated in
Europe PubMed Central
PMC publication ID
3760771
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
Dimensions Publication ID
1030505833
0 references
OpenCitations bibliographic resource ID
211088
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
211088
PMC publication ID
3760771
3 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21248841
retrieved
23 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
211088
stated in
Europe PubMed Central
PMC publication ID
3760771
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
PubMed publication ID
21248841
3 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21248841
retrieved
23 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
211088
stated in
Europe PubMed Central
PMC publication ID
3760771
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21248841%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
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