(Q40736227)

23 September 2017

title

Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain (English)

1 reference

23 September 2017

Hitoshi Kiyoi

1

1 reference

23 September 2017

Ryuzo Ohno

2

1 reference

23 September 2017

Ryuzo Ueda

3

1 reference

23 September 2017

Hidehiko Saito

4

1 reference

23 September 2017

Tomoki Naoe

5

1 reference

23 September 2017

language of work or name

English

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publication date

1 April 2002

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23 September 2017

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23 September 2017

volume

21

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23 September 2017

issue

16

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23 September 2017

page(s)

2555-2563

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Hsp90 & Co. - a holding for folding

23 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205332

Intramolecular interactions between the juxtamembrane domain and phosphatase domains of receptor protein-tyrosine phosphatase RPTPmu. Regulation of catalytic activity

21 January 2018

1 reference

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Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product

21 January 2018

1 reference

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SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain

21 January 2018

1 reference

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Inhibition of spontaneous receptor phosphorylation by residues in a putative alpha-helix in the KIT intracellular juxtamembrane region.

21 January 2018

1 reference

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SHC and SHIP phosphorylation and interaction in response to activation of the FLT3 receptor

21 January 2018

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A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations

21 January 2018

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Molecular chaperones: the busy life of Hsp90.

21 January 2018

1 reference

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Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia

21 January 2018

1 reference

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Role of c-kit receptor tyrosine kinase in the development, survival and neoplastic transformation of mast cells

21 January 2018

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Switching signals on or off by receptor dimerization

21 January 2018

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Hsp90 chaperones protein folding in vitro.

21 January 2018

1 reference

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Insights into Src kinase functions: structural comparisons

21 January 2018

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Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

21 January 2018

1 reference

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Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling

21 January 2018

1 reference

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In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

21 January 2018

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c-Kit and c-kit mutations in mastocytosis and other hematological diseases.

21 January 2018

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7 January 2021

The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding

1 reference

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7 January 2021

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

1 reference

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7 January 2021

Tandem duplications of the FLT3 receptor gene are associated with leukemic transformation of myelodysplasia

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7 January 2021

Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia. The Children's Cancer and Leukemia Study Group, Japan

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7 January 2021

Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia. Leukemia Study Group of the Ministry of Health and Welfare (Kohseisho)

1 reference

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7 January 2021

Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

1 reference

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7 January 2021

Prognostic value of internal tandem duplication of the FLT3 gene in childhood acute myelogenous leukemia

1 reference

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7 January 2021

RTK mutations and human syndromes: when good receptors turn bad

1 reference

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7 January 2021

Biological characteristics and prognosis of adult acute myeloid leukemia with internal tandem duplications in the Flt3 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205332

7 January 2021

Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205332

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205332

1 reference

Dimensions Publication ID

23 September 2017

1042923053

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1 reference