(Q40341891)

19 September 2017

title

Chimeric molecules to target proteins for ubiquitination and degradation (English)

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19 September 2017

main subject

protein ubiquitination

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Kathleen M Sakamoto

1

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19 September 2017

language of work or name

English

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publication date

1 January 2005

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19 September 2017

published in

Methods in Enzymology

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19 September 2017

volume

399

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19 September 2017

page(s)

833-847

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Regulatory functions of ubiquitination in the immune system

19 September 2017

cites work

1 reference

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Ubiquitin-mediated proteolysis: biological regulation via destruction

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7 January 2021

SCF and Cullin/Ring H2-based ubiquitin ligases

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

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Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin.

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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Arginine-based molecular transporters: the synthesis and chemical evaluation of releasable taxol-transporter conjugates

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Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

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7 January 2021

Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

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7 January 2021

Development of Protacs to Target Cancer-promoting Proteins for Ubiquitination and Degradation

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7 January 2021

Chemical genetic control of protein levels: selective in vivo targeted degradation

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7 January 2021

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

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7 January 2021

Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome

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Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

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The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters

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The antiangiogenic agent TNP-470 requires p53 and p21CIP/WAF for endothelial cell growth arrest

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7 January 2021

10.1016/S0076-6879(05)99054-X

Identifiers

DOI

1 reference

19 September 2017

1 reference