(Q38817737)

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1 March 2020

title

Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL (English)

1 reference

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1 March 2020

3

1 reference

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1 March 2020

author name string

Ashton C Lai

1

1 reference

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1 March 2020

Momar Toure

2

1 reference

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1 March 2020

Jemilat Salami

4

1 reference

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1 March 2020

Saul Jaime-Figueroa

5

1 reference

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1 March 2020

Eunhwa Ko

6

1 reference

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1 March 2020

John Hines

7

1 reference

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1 March 2020

Craig M Crews

8

1 reference

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1 March 2020

language of work or name

English

0 references

publication date

23 November 2015

1 reference

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Angewandte Chemie International Edition

1 March 2020

published in

1 reference

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1 March 2020

volume

55

1 reference

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1 March 2020

issue

2

1 reference

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1 March 2020

page(s)

807-810

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Catalytic in vivo protein knockdown by small-molecule PROTACs.

1 March 2020

cites work

1 reference

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Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4.

9 September 2017

1 reference

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Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4.

9 September 2017

1 reference

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DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation

9 September 2017

1 reference

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Kinase-independent mechanisms of resistance of leukemia stem cells to tyrosine kinase inhibitors

9 September 2017

1 reference

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A comprehensive mathematical model for three-body binding equilibria

9 September 2017

1 reference

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Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α

9 September 2017

1 reference

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Structural and Spectroscopic Analysis of the Kinase Inhibitor Bosutinib and an Isomer of Bosutinib Binding to the Abl Tyrosine Kinase Domain

9 September 2017

1 reference

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Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction

9 September 2017

1 reference

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Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival

9 September 2017

1 reference

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Development of target protein-selective degradation inducer for protein knockdown.

9 September 2017

1 reference

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BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: a review

9 September 2017

1 reference

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Molecular biology of bcr-abl1-positive chronic myeloid leukemia

9 September 2017

1 reference

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The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants

9 September 2017

1 reference

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Regulation of the c-Abl and Bcr-Abl tyrosine kinases

9 September 2017

1 reference

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A novel mechanism for imatinib mesylate-induced cell death of BCR-ABL-positive human leukemic cells: caspase-independent, necrosis-like programmed cell death mediated by serine protease activity

9 September 2017

1 reference

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Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)

9 September 2017

1 reference

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Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

9 September 2017

1 reference

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

9 September 2017

1 reference

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BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia

9 September 2017

1 reference

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BCR-ABL-induced adhesion defects are tyrosine kinase-independent

9 September 2017

1 reference

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25 September 2017

Identifiers

DOI

10.1002/ANIE.201507634

1 reference

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1 March 2020

1 reference

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1 March 2020

PubMed publication ID

26593377

1 reference