(Q35550068)

English

Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia

scientific article published on February 2015

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

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object named as

John C Byrd

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Europe PubMed Central

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8 August 2017

6

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Nyla A Heerema

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Europe PubMed Central

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8 August 2017

Michael R Grever

7

object named as

Michael R Grever

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

5

object named as

Amy M Lehman

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

1

object named as

Yuh-Ying Yeh

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

4

object named as

Emilia Mahoney

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

author name string

Rong Chen

2

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Joshua Hessler

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

William Plunkett

8

1 reference

Europe PubMed Central

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8 August 2017

Amy J Johnson

10

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Europe PubMed Central

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8 August 2017

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publication date

1 February 2015

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Europe PubMed Central

PubMed publication ID

8 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

2667-2679

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells

1 reference

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Cyclin-dependent kinase inhibitor therapy for hematologic malignancies

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Genomic approaches to chronic lymphocytic leukemia

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The cyclin-dependent kinase inhibitor SCH 727965 (dinacliclib) induces the apoptosis of osteosarcoma cells

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Dinaciclib (SCH 727965), a novel and potent cyclin-dependent kinase inhibitor.

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Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes.

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Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia

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The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

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Molecular evolution of the RNA polymerase II CTD.

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Cracking the RNA polymerase II CTD code

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Generation of HIV-1-based lentiviral vector particles

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Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

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Flavopiridol causes early mitochondrial damage in chronic lymphocytic leukemia cells with impaired oxygen consumption and mobilization of intracellular calcium

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Novel agents and strategies for treatment of p53-defective chronic lymphocytic leukemia

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Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia

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Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186

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CDK9/CYCLIN T1 expression during normal lymphoid differentiation and malignant transformation.

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Suppression of survivin phosphorylation on Thr34 by flavopiridol enhances tumor cell apoptosis.

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The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in multiple myeloma cells through transcriptional repression and down-regulation of Mcl-1.

1 reference

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Cdk9‐55: A new player in muscle regeneration

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.2096

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

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