(Q35748744)

10 August 2017

title

Protein degradation: Prime time for PROTACs (English)

1 reference

Corrigendum: Protein degradation: Prime time for PROTACs.

10 August 2017

corrigendum / erratum

0 references

Raymond J Deshaies

1

0 references

publication date

1 August 2015

1 reference

10 August 2017

published in

Nature Chemical Biology

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10 August 2017

volume

11

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10 August 2017

issue

9

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10 August 2017

page(s)

634-635

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Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

10 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1887

Small-molecule control of intracellular protein levels through modulation of the ubiquitin proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1887

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1887

DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1887

Catalytic in vivo protein knockdown by small-molecule PROTACs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1887

Identification of a primary target of thalidomide teratogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1887

Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1887

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1887

Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1887

Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1887

Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26284668

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26284668

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26284668

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.1887

1 reference

10 August 2017

1 reference