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Thesis Interpretation Tables

1) The study evaluated gender distribution, clinical features, age, and laboratory parameters of benign and malignant pancreatic tumors. 2) Malignant tumors were more common in males and were associated with weight loss, anorexia, higher CA 19-9 and bilirubin levels compared to benign tumors. 3) CA 19-9, alkaline phosphatase, and bilirubin levels showed moderate to good ability to differentiate between benign and malignant tumors, with CA 19-9 showing the best performance.

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93 views7 pages

Thesis Interpretation Tables

1) The study evaluated gender distribution, clinical features, age, and laboratory parameters of benign and malignant pancreatic tumors. 2) Malignant tumors were more common in males and were associated with weight loss, anorexia, higher CA 19-9 and bilirubin levels compared to benign tumors. 3) CA 19-9, alkaline phosphatase, and bilirubin levels showed moderate to good ability to differentiate between benign and malignant tumors, with CA 19-9 showing the best performance.

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m29here
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© Attribution Non-Commercial (BY-NC)
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Table 1.

Gender distribution

Sex
Pathological findings Chi-
Benign Malignant Total square
n % n % n % value P-value
F 9 47.4 11 35.5 20 40
   
M 10 52.6 20 64.5 30 60 0.693 .405
Total 19 100 31 100 50 100    

Table 2. Clinical features

Clinical Pathological findings


Features Chi-
Benign Malignant Total square
n % n % n % value P-value
Anorexia
NO 10 52.6 0 0 10 20    
YES 9 47.4 31 100 40 80 20.395 0.000
Total   19 100 31 100 50 100    
Loss of weight

NO 17 89.5 7 22.6 24 48
   
YES 2 10.5 24 77.4 26 52 21.118 0.000

19 100 31 100 50 100


Total     
Table 3. Age and Laboratory parameters

Parameters Pathological findings


Benign Malignant
Mean SD Mean SD t-value  P-value
Age 62.47 11.946 63.06 9.515 0.193 0.848
CA 19-9 125.868 242.5380 642.494 404.3299 5.031 0.000
Alkaline Phosphatase 435.89 240.479 511.87 311.838 0.908 0.368
Total Serum Bilirubin 164.71 108.156 278.90 151.595 2.862 0.006

AUC 0.858

Fig. CA19-9
AUC 0.568

Fig. Alkaline Phosphatase

AUC 0.731

Fig. Total serum bilirubin


Table 4. ROC parameters of Laboratory findings

Sensitivity Specificity Area under


Parameter Cut-off value (%) (%) Curve (AUC) P-value
Total Bilirubin (µmol/L) 135.32 52.6 83.9 0.731 0.007
Alkaline Phosphatase (U/L) 478 63.2 41.9 0.568 0.424
CA 19-9 (U/ml) 100 73.9 77.4 0.858 0.001

Area Under the Curve

Test Result Variable(s) Asymptotic 95% Confidence


Interval
a b
Area Std. Error Asymptotic Sig. Lower Bound Upper Bound

CA19_9 .858 .057 .000 .747 .970

dimensio n0
ALP .568 .084 .424 .403 .733

TSB .731 .073 .007 .587 .875

The test result variable(s): CA19_9, ALP, TSB has at least one tie between the positive actual state group
and the negative actual state group. Statistics may be biased.
a. Under the nonparametric assumption
b. Null hypothesis: true area = 0.5
Fig. AP Benign

Area Under the Curve


Test Result Variable(s):AP

Asymptotic 95% Confidence


Interval

Area Std. Errora Asymptotic Sig.b Lower Bound Upper Bound

.845 .055 .000 .737 .952

The test result variable(s): AP has at least one tie between the positive actual
state group and the negative actual state group. Statistics may be biased.
a. Under the nonparametric assumption
b. Null hypothesis: true area = 0.5
Fig. PP malignant

Area Under the Curve


Test Result Variable(s):PP

Asymptotic 95% Confidence


Interval

Area Std. Errora Asymptotic Sig.b Lower Bound Upper Bound

.829 .067 .000 .698 .959

The test result variable(s): PP has at least one tie between the positive actual
state group and the negative actual state group. Statistics may be biased.
a. Under the nonparametric assumption
b. Null hypothesis: true area = 0.5

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