Genotoxic anti-cancer agents and their relationship to DNA damage, mitosis, and checkpoint adaptation in proliferating cancer cells (Q26851196)

Roy Golsteyn

series ordinal

2

1 reference

International Journal of Molecular Sciences

language of work or name

1 reference

25 February 2014

6 references

3 April 2019

20 August 2019

14 September 2020

24 January 2021

8 February 2021

6 references

3 April 2019

20 August 2019

14 September 2020

24 January 2021

8 February 2021

15

1 reference

issue

3

1 reference

page(s)

3403-31

1 reference

Creative Commons Attribution 3.0 Unported

copyright license

5 references

3 April 2019

20 August 2019

14 September 2020

24 January 2021

on focus list of Wikimedia project

8 February 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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Comprehensive molecular characterization of human colon and rectal cancer

7 April 2017

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Hallmarks of Cancer: The Next Generation

7 April 2017

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The DNA-damage response in human biology and disease

7 April 2017

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Targeting DNA topoisomerase II in cancer chemotherapy

7 April 2017

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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

7 April 2017

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Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase

7 April 2017

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

7 April 2017

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ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts

7 April 2017

1 reference

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Rapid activation of ATR by ionizing radiation requires ATM and Mre11

7 April 2017

1 reference

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ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

7 April 2017

1 reference

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Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases

7 April 2017

1 reference

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Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention

7 April 2017

1 reference

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Replication protein A-mediated recruitment and activation of Rad17 complexes

7 April 2017

1 reference

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Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

7 April 2017

1 reference

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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

7 April 2017

1 reference

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Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

7 April 2017

1 reference

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Instability and decay of the primary structure of DNA

7 April 2017

1 reference

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DNA damage associated with mitosis and cytokinesis failure

7 April 2017

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Mechanism of replication blocking and bypass of Y-family polymerase by bulky acetylaminofluorene DNA adducts

7 April 2017

1 reference

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CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases

7 April 2017

1 reference

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The structural basis for the mutagenicity of O6-methyl-guanine lesions

7 April 2017

1 reference

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The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation

7 April 2017

1 reference

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Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

7 April 2017

1 reference

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The DNA damage response: putting checkpoints in perspective

7 April 2017

1 reference

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

7 April 2017

1 reference

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Genome maintenance mechanisms for preventing cancer

7 April 2017

1 reference

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The initial clinical trial of nitrogen mustard

7 April 2017

1 reference

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Oxidative DNA damage: mechanisms, mutation, and disease

7 April 2017

1 reference

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Human claspin is required for replication checkpoint control

7 April 2017

1 reference

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5-Fluorouracil: mechanisms of action and clinical strategies

7 April 2017

1 reference

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

7 April 2017

1 reference

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Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1

7 April 2017

1 reference

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ATR and ATRIP: partners in checkpoint signaling

7 April 2017

1 reference

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DNA double-strand breaks: signaling, repair and the cancer connection

7 April 2017

1 reference

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14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

7 April 2017

1 reference

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The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer

7 April 2017

1 reference

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Formation and repair of interstrand cross-links in DNA

7 April 2017

1 reference

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Cell-cycle checkpoints and cancer

7 April 2017

1 reference

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Cell death by mitotic catastrophe: a molecular definition

7 April 2017

1 reference

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Hus1 acts upstream of chk1 in a mammalian DNA damage response pathway

7 April 2017

1 reference

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DNA repair pathways as targets for cancer therapy

7 April 2017

1 reference

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Topoisomerase I inhibitors: camptothecins and beyond

7 April 2017

1 reference

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TopBP1 activates the ATR-ATRIP complex

7 April 2017

1 reference

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

7 April 2017

1 reference

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Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

7 April 2017

1 reference

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DNA-damaging agents in cancer chemotherapy: serendipity and chemical biology

7 April 2017

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Chemotherapy induced DNA damage response: convergence of drugs and pathways

28 September 2017

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Detection of DNA-protein crosslinks (DPCs) by novel direct fluorescence labeling methods: distinct stabilities of aldehyde and radiation-induced DPCs.

28 September 2017

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Human cells enter mitosis with damaged DNA after treatment with pharmacological concentrations of genotoxic agents

28 September 2017

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Cancer and radiation therapy: current advances and future directions

28 September 2017

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Mechanisms of free radical-induced damage to DNA.

28 September 2017

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Balancing repair and tolerance of DNA damage caused by alkylating agents

28 September 2017

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Targeting the S and G2 checkpoint to treat cancer.

28 September 2017

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Mechanism of DNA depurination by carcinogens in relation to cancer initiation

28 September 2017

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Characterization of novel checkpoint kinase 1 inhibitors by in vitro assays and in human cancer cells treated with topoisomerase inhibitors.

28 September 2017

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Strategies to improve radiotherapy with targeted drugs

28 September 2017

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Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair

28 September 2017

1 reference

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Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair

28 September 2017

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Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

28 September 2017

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Endogenous versus exogenous DNA adducts: their role in carcinogenesis, epidemiology, and risk assessment

28 September 2017

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ATR: a master conductor of cellular responses to DNA replication stress

28 September 2017

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Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases kappa and zeta in human cells

28 September 2017

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CDK inhibitors: from the bench to clinical trials.

28 September 2017

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gammaH2AX: a sensitive molecular marker of DNA damage and repair

28 September 2017

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The Blood and Bone Marrow in Yelloe Cross Gas (Mustard Gas) Poisoning: Changes produced in the Bone Marrow of Fatal Cases

28 September 2017

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DNA damage checkpoint inactivation: adaptation and recovery

28 September 2017

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Cisplatin-induced DNA damage activates replication checkpoint signaling components that differentially affect tumor cell survival

28 September 2017

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Apoptosis and non-apoptotic deaths in cancer development and treatment response

28 September 2017

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Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.

28 September 2017

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Death through a tragedy: mitotic catastrophe

28 September 2017

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G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer

28 September 2017

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Mismatch repair-dependent processing of methylation damage gives rise to persistent single-stranded gaps in newly replicated DNA.

28 September 2017

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DNA damage induces two distinct modes of cell death in ovarian carcinomas

28 September 2017

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The resurgence of platinum-based cancer chemotherapy

28 September 2017

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The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1.

28 September 2017

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Loss of ataxia telangiectasia mutated- and Rad3-related function potentiates the effects of chemotherapeutic drugs on cancer cell survival

28 September 2017

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DNA damage checkpoints: from initiation to recovery or adaptation

28 September 2017

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Adaptation to the ionizing radiation-induced G2 checkpoint occurs in human cells and depends on checkpoint kinase 1 and Polo-like kinase 1 kinases

28 September 2017

1 reference

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Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations.

28 September 2017

1 reference

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ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage

28 September 2017

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Etoposide, topoisomerase II and cancer

28 September 2017

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Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype

28 September 2017

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Optimal role of temozolomide in the treatment of malignant gliomas.

28 September 2017

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DNA-protein crosslinks: their induction, repair, and biological consequences

28 September 2017

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Advances in radiation therapy: conventional to 3D, to IMRT, to 4D, and beyond

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Temozolomide in the treatment of solid tumours: current results and rationale for dosing/scheduling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Different G2/M accumulation in M059J and M059K cells after exposure to DNA double-strand break-inducing agents.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Cdk1 and Cdk2 complexes (cyclin dependent kinases) in apoptosis: a role beyond the cell cycle

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing Radiation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Alkylation damage in DNA and RNA--repair mechanisms and medical significance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

DNA damage-induced activation of ATM and ATM-dependent signaling pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Repair of DNA covalently linked to protein.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

The role of cyclin-dependent kinases in apoptosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Repair of deaminated bases in DNA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Multicentre phase II and pharmacokinetic study of RFS2000 (9-nitro-camptothecin) administered orally 5 days a week in patients with glioblastoma multiforme

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

DNA and its associated processes as targets for cancer therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Induction of cyclin E and inhibition of DNA synthesis by the novel acronycine derivative S23906-1 precede the irreversible arrest of tumor cells in S phase leading to apoptosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Clinical pharmacokinetics of oxaliplatin: a critical review

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Phase I and pharmacokinetic study of temozolomide on a daily-for-5-days schedule in patients with advanced solid malignancies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Review of the comparative pharmacology and clinical activity of cisplatin and carboplatin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

The increment of micronucleus frequency in cervical carcinoma during irradiation in vivo and its prognostic value for tumour radiocurability.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Secondary leukemia or myelodysplastic syndrome after treatment with epipodophyllotoxins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

How does radiation kill cells?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Oxidized, deaminated cytosines are a source of C --> T transitions in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Spontaneous premature chromosome condensation and mitotic catastrophe following irradiation of HeLa S3 cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Cisplatin and DNA repair in cancer chemotherapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Topoisomerase Poisons: Harnessing the Dark Side of Enzyme Mechanism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Radiation-induced apoptosis: Relevance to radiotherapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Pharmacokinetics and pharmacodynamics of prolonged oral etoposide in women with metastatic breast cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Relating aromatic hydrocarbon-induced DNA adducts and c-H-ras mutations in mouse skin papillomas: the role of apurinic sites

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Platinum Compounds: a New Class of Potent Antitumour Agents

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Tolerance of normal tissue to therapeutic irradiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

DNA damage induced by alkylating agents and repair pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

THE EFFECT OF GAMMA RAYS ON CELL DIVISION IN THE DEVELOPING RAT RETINA.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Timeline: Chemotherapy and the war on cancer.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Amitotic cell divisions and tumour growth: an alternative model for cell kinetic compartments in solid tumours

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Ratio of 2'-deoxyadenosine-5'-triphosphate/thymidine-5'-triphosphate influences the commitment of human colon carcinoma cells to thymineless death.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Bleomycin, an apoptosis-mimetic drug that induces two types of cell death depending on the number of molecules internalized

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Crosslinking of DNA by busulfan. Formation of diguanyl derivatives

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Molecular spectrum of mutations induced by 5-hydroxymethyl-2'-deoxyuridine in (CHO)-PL61 cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Intrastrand DNA cross-links as tools for studying DNA replication and repair: two-, three-, and four-carbon tethers between the N(2) positions of adjacent guanines

31 May 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Comparative mutational spectra of the nitrogen mustard chlorambucil and its half-mustard analogue in Chinese hamster AS52 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Glioblastoma survival in the United States before and during the temozolomide era.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

An unusual DNA binding compound, S23906, induces mitotic catastrophe in cultured human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Alkylation of guanine in DNA by S23906-1, a novel potent antitumor compound derived from the plant alkaloid acronycine

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Reduced systemic drug exposure by combining intra-arterial chemotherapy with hemoperfusion of regional venous drainage

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Radiation oncology: a century of achievements.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Recovery from checkpoint-mediated arrest after repair of a double-strand break requires Srs2 helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Checkpoint adaptation; molecular mechanisms uncovered

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic cata

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Mitotic catastrophe: a mechanism for avoiding genomic instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

A western blot assay to measure cyclin dependent kinase activity in cells or in vitro without the use of radioisotopes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

High inter- and intrapatient variation in 5-fluorouracil plasma concentrations during a prolonged drug infusion.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Dual modes of death induced by etoposide in human epithelial tumor cells allow Bcl-2 to inhibit apoptosis without affecting clonogenic survival.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975345

Cross-linking of Deoxyribonucleic Acid to Protein following Ultra-Violet Irradiation of Different Cells

28 November 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033403

A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Accumulation of DNA Damage and Cell Death after Fractionated Irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Pharmacokinetics of carboplatin after i.v. administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Changes in S-phase fraction and micronucleus frequency as prognostic factors in radiotherapy of cervical carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Pharmacokinetics of free and total platinum species after short-term infusion of cisplatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Fatal overdosage with cisplatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Pharmacokinetics of cis-diammine-1,1-cyclobutane dicarboxylate platinum(II) in patients with normal and impaired renal function

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Karyoanomalic frequency during radiation therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

CDC5 and CKII control adaptation to the yeast DNA damage checkpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Prediction of radiosensitivity of oral cancers by serial cytological assay of nuclear changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Pharmacokinetics of high-dose etoposide (VP-16-213) administered to cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

The role of cell cycle progression in cisplatin-induced apoptosis in Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Deoxyribonucleoside triphosphate imbalance. 5-Fluorodeoxyuridine-induced DNA double strand breaks in mouse FM3A cells and the mechanism of cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Repair of O6-methylguanine in DNA by demethylation is lacking in Mer- human tumor cell strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

The comet assay: a method to measure DNA damage in individual cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24573252

12 December 2020

Identifiers

DOI

10.3390/IJMS15033403

1 reference

1 reference

1 reference

PubMed publication ID

24573252

1 reference