DNA damage associated with mitosis and cytokinesis failure (Q26991874)

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22 February 2020

review article

1 reference

title

DNA damage associated with mitosis and cytokinesis failure (English)

2 references

PubMed

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22 February 2020

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0 references

1

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22 February 2020

author name string

J Karlseder

series ordinal

2

2 references

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22 February 2020

language of work or name

1 reference

14 January 2013

1 reference

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22 February 2020

2 references

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22 February 2020

volume

32

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PubMed

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22 February 2020

issue

39

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PubMed

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22 February 2020

page(s)

4593-4601

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Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

22 February 2020

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Functional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetuses

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Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

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Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells

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Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

21 March 2017

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Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle

21 March 2017

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The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

21 March 2017

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Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis

21 March 2017

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Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

21 March 2017

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The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

21 March 2017

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Progressive telomere dysfunction causes cytokinesis failure and leads to the accumulation of polyploid cells

21 March 2017

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Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells

21 March 2017

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The spindle-assembly checkpoint in space and time

21 March 2017

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The NoCut pathway links completion of cytokinesis to spindle midzone function to prevent chromosome breakage.

21 March 2017

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TRF2 Protects Human Telomeres from End-to-End Fusions

21 March 2017

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Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

21 March 2017

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Timing and checkpoints in the regulation of mitotic progression

21 March 2017

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Cell death by mitotic catastrophe: a molecular definition

21 March 2017

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A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint

21 March 2017

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Aurora-A kinase is essential for bipolar spindle formation and early development

21 March 2017

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Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E

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MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

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21 March 2017

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21 March 2017

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Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

7 April 2017

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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

7 April 2017

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Chk1 and Chk2 kinases in checkpoint control and cancer

7 April 2017

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Transcriptional consequences of aneuploidy

7 April 2017

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Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells

28 September 2017

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Chromosomal instability and aneuploidy in cancer: from yeast to man

28 September 2017

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Losing balance: the origin and impact of aneuploidy in cancer

28 September 2017

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Cell division control by the Chromosomal Passenger Complex

28 September 2017

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Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

28 September 2017

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A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest

28 September 2017

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DNA breaks and chromosome pulverization from errors in mitosis

28 September 2017

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Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction

28 September 2017

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p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.

28 September 2017

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Aurora-B mediated ATM serine 1403 phosphorylation is required for mitotic ATM activation and the spindle checkpoint

28 September 2017

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Chromosome missegregation in human cells arises through specific types of kinetochore-microtubule attachment errors

28 September 2017

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Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations

28 September 2017

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DNA damage response is suppressed by the high cyclin-dependent kinase 1 activity in mitotic mammalian cells

28 September 2017

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Aurora B dynamics at centromeres create a diffusion-based phosphorylation gradient.

28 September 2017

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The causes and consequences of polyploidy in normal development and cancer

28 September 2017

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New insights into the formation and resolution of ultra-fine anaphase bridges

28 September 2017

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Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events

28 September 2017

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Mitosis in vertebrates: the G2/M and M/A transitions and their associated checkpoints

28 September 2017

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Prolonged Prometaphase Blocks Daughter Cell Proliferation Despite Normal Completion of Mitosis

28 September 2017

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28 September 2017

Mechanisms of aneuploidy

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The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

28 September 2017

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DNA damage signaling in response to double-strand breaks during mitosis

28 September 2017

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Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.

28 September 2017

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p53 suppresses structural chromosome instability after mitotic arrest in human cells

28 September 2017

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Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.

28 September 2017

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Role of prolonged mitotic checkpoint activation in the formation and treatment of cancer

28 September 2017

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Sister chromatid tension and the spindle assembly checkpoint

28 September 2017

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Clearing the way for mitosis: is cohesin a target?

28 September 2017

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TTK/hMps1 mediates the p53-dependent postmitotic checkpoint by phosphorylating p53 at Thr18.

28 September 2017

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Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates

28 September 2017

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The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS, HeLa) cells

28 September 2017

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Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.

28 September 2017

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Extra centrosomes and/or chromosomes prolong mitosis in human cells

28 September 2017

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Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient

28 September 2017

1 reference

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Death through a tragedy: mitotic catastrophe

28 September 2017

1 reference

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Human cancer cells commonly acquire DNA damage during mitotic arrest

28 September 2017

1 reference

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Limiting the proliferation of polyploid cells

28 September 2017

1 reference

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Tetraploidy, aneuploidy and cancer

28 September 2017

1 reference

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ATM is activated by mitotic stress and suppresses centrosome amplification in primary but not in tumor cells

28 September 2017

1 reference

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Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance

28 September 2017

1 reference

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The mitotic checkpoint in cancer and aging: what have mice taught us?

28 September 2017

1 reference

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Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint

28 September 2017

1 reference

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Inhibition of DNA decatenation, but not DNA damage, arrests cells at metaphase

28 September 2017

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Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint".

28 September 2017

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DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint

28 September 2017

1 reference

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Centrosome aberrations: cause or consequence of cancer progression?

28 September 2017

1 reference

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Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1.

28 September 2017

1 reference

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Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells

28 September 2017

1 reference

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Re-staging mitosis: a contemporary view of mitotic progression

28 September 2017

1 reference

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Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase

28 September 2017

1 reference

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Aurora B-mediated abscission checkpoint protects against tetraploidization

28 September 2017

1 reference

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Mitotic catastrophe: a mechanism for avoiding genomic instability.

31 May 2018

1 reference

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Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5.

21 January 2018

1 reference

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Sustained mitotic block elicits DNA breaks: one-step alteration of ploidy and chromosome integrity in mammalian cells.

21 January 2018

1 reference

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DNA damage checkpoint maintains CDH1 in an active state to inhibit anaphase progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.615

Roles of polo-like kinase 1 in the assembly of functional mitotic spindles

21 January 2018

1 reference

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How shelterin solves the telomere end-protection problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.615

Resolution of anaphase bridges in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.615

Survivin is required for stable checkpoint activation in taxol-treated HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.615

Polo-like Kinase 1 Triggers the Initiation of Cytokinesis in Human Cells by Promoting Recruitment of the RhoGEF Ect2 to the Central Spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.615

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms

21 January 2018

1 reference

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31 March 2020

Identifiers

DOI

10.1038/ONC.2012.615

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318447%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

22 February 2020

1030843085

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318447%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

23318447

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318447%20AND%20SRC:MED&resulttype=core&format=json