Akash Full Bio PDF
Akash Full Bio PDF
Akash Full Bio PDF
Solutions
SECTION - A
School/Board Exam. Type Questions
5. In which axis, the volume of thoracic cavity increases during the contraction of external intercostal muscles?
Sol. In dorso-ventral axis, i.e., backward-forward direction.
6. What is vital capacity?
Sol. It is the maximum volume of air a person can breathe in and out after a forceful expiration and inspiration.
7. Give values of alveolar pO2 and alveolar pCO2.
Sol. Alveolar pO2 is equal to 104 mm Hg.
Alveolar pCO2 is equal to 40 mm Hg.
8. What are the three forms in which CO2 is transported by the blood?
Sol. As bicarbonate ions, carbonic acid (dissolved form) and carbaminohaemoglobin.
9. How many O2 molecules can be carried by a single molecule of Hb?
Sol. Four
10. Which respiratory disease is characterised by damaged alveolar walls?
Sol. Emphysema
Sol.
Breathing Respiration
1. It is simply inhalation of fresh air and It is the oxidation of food (glucose) to form
exhalation of foul air. CO2, water and release energy.
2. It is a physical process. It is a biochemical process.
3. No energy is released during this Energy is released during this process.
mechanism.
Sol. In sponges, cell surface gaseous exchange takes place. As in these animals, cells are in direct contact with
environment. Oxygen dissolved in water passes into the cells by diffusion while CO2 liberated by the cells
diffuses out into the surrounding water through the general surface.
Sol. Earthworm : Cuticle is the outermost covering of their body and the underlying epidermis which are utilised
for the exchange of gases by simple diffusion. They are thin, moist and vascular, so that diffusion of gases
takes place easily.
14. Explain the structure which prevents the entry of food into the larynx.
Sol. Epiglottis prevents the entry of food into the larynx during swallowing. It is a leaf-shaped cartilaginous structure
made up of elastic cartilage which covers the glottis during swallowing, so that the food cannot enter into the
larynx.
Sol. It is a straight tube extending upto the mid-thoracic cavity. This tube finally divides into right and left primary
bronchi at the level of 5th thoracic vertebra. It is lined by cartilaginous rings that prevents collapsing.
Sol. The membranes surround the lungs are pleura or pleural membranes. These are two in number and a narrow
space present between the two is known as pleural cavity which is filled with pleural fluid secreted by pleural
membranes. Outer pleural membrane is in close contact with the thoracic cavity and inner one is in close
contact with lung surface.
Sol. External nostrils Nasal chamber Nasopharynx Glottis Trachea Primary bronchi Secondary
bronchi Tertiary bronchi Bronchioles Alveolar ducts Atria Alveolar sac Alveoli
Sol.
Inspiration Expiration
1. Inspiration is a process by which fresh air Expiration is a process by which foul air
enters the lungs. (containing CO2) is expelled out of the
lungs.
2. It is simply the inflow of fresh air. It is simply the outflow of air.
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Solution of Assignment (Set-1) Breathing and Exchange of Gases 29
19. What is the role of external intercostal muscles in inspiration?
Sol. During inspiration, external intercostal muscles contract and lift up the ribs and sternum causing an increase
in the volume of thoracic cavity in dorso-ventral axis that leads to similar
Increase in the volume of pulmonary cavity
Causes
External nostrils Nasal cavities Pharynx Larynx Trachea Bronchi Bronchioles Alveoli
Alveoli Bronchioles Bronchi Trachea Larynx Pharynx Nasal cavities External nostrils
21. How the movement of air into and out of the lungs is carried out? Give an example.
Sol. The movement of air into and out of the lungs is carried out by creating a pressure gradient between lungs
and the atmosphere. Pressure gradient is the pressure difference. For example, pressure of O2 in atmospheric
air is higher than the alveoli because of which O2 diffuses in from atmospheric air.
22. What is meant by vital capacity? List any two categories of people which possess higher vital capacity.
Sol. Vital capacity is the maximum volume of air a person can breathe in after a forceful expiration or the maximum
volume of air a person can breathe out after a forceful inspiration.
Sol. Inspiratory capacity : It is defined as the total volume of air a person can inspire after a normal expiration.
It includes tidal volume and inspiratory reserve volume.
Expiratory capacity : It is defined as the total volume of air a person can expire after a normal inspiration.
It includes tidal volume and expiratory reserve volume.
24. What is partial pressure? How does it help in exchange of O2 between alveoli and blood?
Sol. Partial pressure is the pressure contributed by a single gas in a mixture of gases. It is represented as pO2
(for oxygen) and pCO2 (for carbon dioxide). Gases move from their higher partial pressure to their lower partial
pressure.
It helps in exchange of O2 between alveoli and blood. As the pO2 in alveoli is higher, i.e., 104 mm Hg than
that present in the blood, i.e., 40 mm Hg. So, O2 diffuses into the blood from higher pO2 to lower pO2.
25. Why is O2 moved from blood to tissues whereas CO2 from tissues to blood?
Sol. This is due to partial pressure gradient. The pO2 is higher in systemic arteries carrying oxygenated blood, i.e.,
95 mm Hg than that in tissues, i.e., 40 mm Hg. So, O2 moves from systemic arteries to body tissues, whereas
CO2 moves from tissues to blood because the pCO2 is higher in tissues, i.e., 45 mm Hg than that in blood
capillaries, i.e., 40 mm Hg.
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30 Breathing and Exchange of Gases Solution of Assignment (Set-1)
26. Give graphic presentation of O2-dissociation curve. Which part of graph indicates association of O2 with Hb?
Sol. %
100
Percentage saturation of haemoglobin
Shift to Left
80 Normal
Shift to right
60
P50
40
20
0
0 20 40 60 80 100 120
Partial pressure of oxygen (mm Hg)
The association of O2 with Hb is indicated by when the graph shifts towards the left-hand side of the normal
curve.
Hb CO2
HbCO 2
Carbaminohaemoglobin
It is transported to the alveoli, from where it is exhaled out as CO2 because dissociation of CO2 and Hb occurs
in the alveoli.
28. For which gas O2 and CO2, Hb has high affinity? Write the equation showing the binding of Hb with O2 and
CO2.
Sol. Hb has high affinity for O2 than CO2.
Binding of O2 with Hb :
Hb O 2
HbO 2
Haemoglobin Oxygen Oxyhaemoglobin
Hb CO2
HbCO 2
Haemoglobin Carbon Carbamino-
dioxide haemoglobin
36. First step of respiration is breathing. Write down the further steps involved in respiration.
Sol. Further steps involved in respiration are
1. Diffusion of gases between alveoli and blood : Diffusion of gases O2 and CO2 takes place across
the alveolar membrane to the blood capillaries surrounding it. The membrane is very thin and richly supplied
with blood capillaries.
2. Transport of gases : Blood is the medium for transport of gases O2 and CO2, which transports O2 to
the body cells from alveoli and CO2 from the body cells to alveoli.
3. Diffusion of gases between blood and tissues : O2 is diffused from blood to tissues and CO2 is diffused
from tissues to blood.
4. Utilisation of O2 : O2 is used by the body cells for the release of energy. Breakdown of glucose occurs
in presence of O2 which produces CO2, water and energy.
Abdominal muscles : These muscles relax and allow compression of abdominal organs by the diaphragm.
Due to which the volume of thoracic cavity increases.
As a result,
38. Explain the role of external intercostal muscles in creating low pressure within the pulmonary cavity.
Sol. External intercostal muscles : These muscles are present between the ribs. The contraction of these muscles
lifts up the ribs and sternum causing an increase in the volume of the thoracic cavity in the dorso-ventral axis,
i.e., backward-forward direction.
Leads to
Increase in the volume of thoracic cavity Similar increase in the volume of
pulmonary cavity
Causes
Causes
(ii) Total Lung Capacity : It is defined as the total volume of air present in the lungs and the respiratory
passage after a maximum inspiration. It includes residual volume, expiratory reserve volume, tidal volume
and inspiratory reserve volume. In other words, it is the combination of vital capacity and residual volume.
It is about 5000 ml to 6000 ml.
The pO2 in the atmospheric air is higher, i.e., 159 mm Hg than that in the alveoli, i.e., 104 mm Hg and pO2
in alveoli is higher than that in the deoxygenated blood in the capillaries of the pulmonary arteries (40 mm
Hg). As we know, gases diffuse from their higher partial pressure to their lower partial pressure. Therefore, O2
moves from atmospheric air to alveoli and then finally to blood. In relation to CO2, movement is in opposite
direction. The pCO2 is higher in deoxygenated blood (45 mm Hg) than that in alveoli (40 mm Hg) and it is
further low in atmospheric air, i.e., 0.3 mm Hg. Therefore, CO2 moves from deoxygenated blood to alveoli and
finally to atmospheric air.
41. Define diffusion. Explain with the help of diagram, the structure of alveolar-capillary membrane.
Sol. Diffusion is defined as the movement of molecules (ions, gases) from their higher concentration/pressure to
their lower concentration/pressure region.
(iii) Basement substance : In between thin squamous epithelium of alveoli and endothelium of alveolar
capillaries, basement substance is present.
Air
Basement
Alveolar wall substance
(one-celled thick)
Alveolar cavity
Blood
capillary
Red blood
cell
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34 Breathing and Exchange of Gases Solution of Assignment (Set-1)
Sol. Conditions which are favourable for the association of O2 and Hb in lungs are
(i) High pO2
43. Explain the role of medulla and pons in the regulation of respiration.
Sol. In medulla and pons, respiratory centres are present which regulate the rate of respiration. These centres are
respiratory rhythm centre present in medulla region of brain and pneumotaxic centre is present in pons region
of brain.
(i) Respiratory rhythm centre : It can either cause expiration or inspiration according to the neurons which
are activated and thereby, regulate the respiratory rhythm according to the need of the body.
(ii) Pneumotaxic centre : It moderates the function of respiratory rhythm centre. The neural signal from this
centre can reduce the duration of inspiration and thereby alter the respiratory rate.
44. How is rate of respiration regulated by chemosensitive area and receptors present in carotid artery?
Sol. Chemosensitive area : This area gets activated when the level of CO2 and H+ ions increases which inturn
activates the respiratory rhythm centre for altering the rate of respiration. This area is located adjacent to the
respiratory rhythm centre.
Receptors associated with carotid artery also affect the rate of respiration. The receptors present in carotid
artery are chemoreceptors sensitive to chemicals or substances such as CO2 and H+ ions. These receptors
work according to the level of CO2 and H+ ions in blood. Increased concentration of CO2 in blood lowers its
pH because of which the rate of respiration increases to eliminate the excess of CO2 from the body.
45. Give the meaning of ‘Emphysema’. What are the causes and symptoms of this respiratory disease?
Sol. The word ‘Emphysema’ means ‘full of air’ or ‘inflation’.
Causes : The major cause is excessive cigarette smoking. Others may include inhalation of smoke or toxic
substances over a period of time.
Symptoms : The walls of alveoli are damaged due to excessive smoking, loss of elasticity of walls of
bronchioles and alveoli. Due to this, the surface area for exchange of gases is reduced. Alveolar sacs remain
filled with air even after expiration. The lungs remain inflated as exhalation becomes difficult.
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Solution of Assignment (Set-1) Breathing and Exchange of Gases 35
SECTION - B
Model Test Paper
5. To which axis, the volume of thoracic cavity increases due to contraction of diaphragm?
Sol. In anterio-posterior axis in rabbit and lengthwise in man.
8. A person is working in a stone-breaking factory from long time. From which type of respiratory disease he can
suffer?
Sol. Occupational respiratory disease, i.e., silicosis.
9. Why is difference in the respiratory organs of tadpole larva of frog and an adult frog?
Sol. Frog is an amphibian, it has dual mode of life. During larval form, it lives in water so uses gills for respiration,
whereas adult form lives on land thereby using moist skin and lungs as respiratory organs.
11. Which conditions affect the binding of CO2 with Hb in tissues and alveoli?
Sol. Conditions are
Tissues Alveoli
High pCO2 Low pCO2
Low pO2 High pO2
These are responsible for binding more These are responsible for dissociation of
CO2 with Hb. CO2 from carbaminohaemoglobin.
Hb + CO2 HbCO2 HbCO2 Hb + CO2
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36 Breathing and Exchange of Gases Solution of Assignment (Set-1)
12. What will happen to pleural membranes if pleural fluid is absent between them?
Sol. The membranes will be damaged due to absence of pleural fluid between them as it lubricates the pleural
membranes, so that they may slide over each other without friction during breathing.
Sol. It is the chemical reactions from which an organism derives energy, takes place within the cells. It is
accompanied by the utilisation of O2 for the chemical reaction, i.e., oxidation of glucose.
Reaction is
C6H12O6 + 6O2
6CO 2
+ 6H2O + Energy
Glucose Eliminated out
of the body
14. How is the pressure of intrapulmonary cavity decreases due to relaxation of abdominal muscles?
Sol. After relaxation, these muscles cause the compression of abdominal organs by the diaphragm due to which
volume of thoracic cavity increases which leads to similar increase in the volume of pulmonary cavity. Due to
which pressure of intrapulmonary cavity decreases.
Each polypeptide chain carries a haem group and each haem group carries an iron atom to which O2 binds.
CO2 binds with the amino group of globin which is a protein portion of Hb.
(i) Branching network of bronchi : It includes primary, secondary and tertiary bronchi.
(ii) Bronchioles : These are the terminal branching of tertiary bronchi, gives rise to a number of alveoli.
(iii) Alveoli : These are balloon-like structures for the exchange of gases arise from bronchioles.
17. Define P50. Which factors favour the dissociation of O2 from Hb occurs in tissues?
Sol. The partial pressure of O2 at which the haemoglobin saturation is 50% is called P50.
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Solution of Assignment (Set-1) Breathing and Exchange of Gases 37
18. We know that about 7% of CO2 is transported as dissolved form, about 70% is transported as bicarbonate
ions. How the remaining percentage of O2 is transported which is about 20–25%?
Sol. Remaining percentage, i.e., about 20–25% of CO2 is transported as carbaminohaemoglobin. CO2 that enters
the RBC, forms a reversible compound, i.e., carbaminohaemoglobin (HbCO2) by binding with globin part of
haemoglobin.
Hb + CO2
HbCO 2
Carbaminohaemoglobin
19. Explain how the CO2 and H+ ions affect the rate of respiration?
Sol. Increase in CO2 and H+ ions activate the chemosensitive area which in turn can signal the respiratory rhythm
centre to increase the rate of respiration, so that these substances are eliminated out.
Receptors present in aortic arch and carotid artery also recognise the changes in CO2 and H+ ions
concentration and send signals to respiratory rhythm centre to alter the rate of respiration.
20. Explain a chronic disorder which occurs due to excessive cigarette smoking.
Sol. Emphysema is the chronic disorder occurs due to excessive cigarette smoking.
In this disease, the walls of alveoli are damaged due to which surface area for exchange of gases is reduced.
Alveolar sacs remain filled with air even after expiration. The lungs remain inflated as exhalation becomes
difficult. This disease can be prevented by avoiding cigarette smoking.
It is red coloured iron containing pigment present in RBCs. It binds with O2 in a reversible manner to form
oxyhaemoglobin (OxyHb) and transports it.
In lungs
Hb + O2 HbO2
Haemoglobin Oxygen Tissues Oxyhaemoglobin
(OxyHb)
O2 binds with Hb at the lungs surface and gets dissociated at the tissues. Under the high partial pressure,
i.e., 95 mm Hg oxygen easily binds with Hb in the pulmonary blood capillaries. When this oxygenated
blood reaches to different tissues, the pO2 decreases and the bonds holding oxygen to Hb become
unstable. As a result, oxygen is released from blood capillaries to tissues where it is utilised for oxidation
of glucose.
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38 Breathing and Exchange of Gases Solution of Assignment (Set-1)
23. Draw a well-labelled diagram of respiratory organ of humans and explain the respiratory surface, i.e., alveoli.
Sol. Epiglottis
Larynx
Trachea
Tertiary bronchus
Cut end of rib Pleural membranes
Alveoli
Lung Pleural fluid
Bronchiole
Diaphragm
Bronchioles give rise to a number of alveoli. There are about 300 millions of alveoli in two lungs. The membrane
of alveoli is very thin, irregular and richly supplied with blood vessels. Due to very close contact of blood vessels
with alveoli, the exchange of gases takes place easily.
Bronchioles
Alveolar ducts
Atria
Alveolar sacs
Lead to Lead to Lead to
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Chapter 5
Solutions
SECTION - A
Objective Type Questions
1. The process of oxidation of glucose during which CO2, H2O and energy are produced is known as
(1) Breathing (2) Inspiration (3) Respiration (4) Expiration
Sol. Answer (3)
Breathing = Inspiration (Inhalation of air) + Expiration (Exhalation of air)
Respiration is the process of oxidation of food in which CO2, H2O and energy is/are produced.
4. Which animal among the following respires via buccal cavity, moist skin and lungs?
(1) Hydra (2) Frog (3) Sycon (4) Earthworm
Sol. Answer (2)
Frogs can respire by their moist skin, buccal cavity and lungs as they live on land and its larval form i.e.
tadpole which lives in water respire through gills.
Hydra, Sycon : No well-developed respiratory system, exchange of gases by simple diffusion.
Earthworm : Moist cuticle.
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52 Breathing and Exchange of Gases Solution of Assignment (Set-2)
5. Respiratory organs in aquatic arthropods like cray fish, prawn and molluscs like Unio are
(1) Body wall (2) Lungs (3) Trachea (4) Gills
Sol. Answer (4)
Aquatic arthropods (Crustacean) respire through gills.
9. A thin-elastic cartilaginous flap which prevents the entry of food into the larynx is known as
(1) Glottis (2) Wind pipe (3) Epiglottis (4) Bronchiole
Sol. Answer (3)
Epiglottis covers the glottis during swallowing of food.
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Solution of Assignment (Set-2) Breathing and Exchange of Gases 53
Sol. Answer (4)
The trachea divides into right and left primary bronchi at the level of 5th thoracic vertebra.
16. Which muscles help us to increase the strength of inspiration and expiration?
(1) Cardiac muscles (2) Abdominal muscles
(3) Internal intercostal muscles (4) Both (2) & (3)
Sol. Answer (4)
Cardiac muscle i.e., muscle of heart, it do not have any role in inspiration and expiration.
Rest two muscles i.e., abdominal and internal intercostal muscle undergo contraction and increase the strength
of expiration.
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54 Breathing and Exchange of Gases Solution of Assignment (Set-2)
19. The volume of air remaining in the lungs even after a forceful expiration is
(1) Tidal volume (2) Residual volume
(3) Inspiratory reserve volume (4) Expiratory reserve volume
Sol. Answer (2)
(1) Tidal volume (500 ml) : It is the volume of air a person can inspired or expired during normal breathing.
(3) Inspiratory reserve volume (2500 – 3000 ml) : The additional or extra volume of air, a person can expire
by forceful expiration.
(4) Expiratory reserve volume (1000 – 1100 ml) : The additional or extra volume of air, a person can expire
by forceful expiration.
20. What is the main site of human respiratory system where exchange of gases occurs?
(1) Alveoli (2) Bronchiole
(3) Primary and secondary bronchi (4) Trachea
Sol. Answer (1)
The membrane of alveoli is very thin, irregular and richly supplied with blood vessels. Due to very close contact
of blood vessels with alveoli, the exchange of gases takes place easily.
(1) pO and pCO (2) pO and pCO (3) pO2 and pCO2 (4) O2p and CO2p
2
22. What will be the pO2 and pCO2 in atmospheric air as compared to alveoli?
(1) High pO2 and low pCO2 (2) High pCO2 and low pO2
(3) Both are equal (pCO2 = pO2) (4) Low pO2 and low pCO2
Sol. Answer (1)
In atmospheric air : pO2 = 159 mmHg
pCO2 = 0.3 mmHg
In alveoli : pO2 = 104 mmHg
pCO2 = 40 mmHg
23. What is the value of pCO2 in atmospheric air, alveoli and tissues respectively?
(1) 0.3 mm Hg, 40 mm Hg and 95 mm Hg
(2) 95 mm Hg, 40 mm Hg and 159 mm Hg
(3) 45 mm Hg, 0.3 mm Hg and 40 mm Hg
(4) 0.3 mm Hg, 40 mm Hg and 45 mm Hg
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Solution of Assignment (Set-2) Breathing and Exchange of Gases 55
Sol. Answer (4)
CO2 0.3 40 45 40 45
In lungs
Hb O2
HbO2
In tissue
(Haemoglobin) (Oxygen) (Oxyhaemoglobin)
Hb CO2
HbCO2
(Carbon dioxide) (Carbamino-haemoglobin)
Hb CO
HbCO
(Carbon monoxide) (Carboxy haemoglobin)
(1)
26.
Hb + O2 HbO2
(2)
Lungs
Hb + O2
HbO2
Tissue
27. A graph is plotted between pO2 and percentage saturation of Hb with O2 is known as
(1) O2 association curve (2) CO2-O2 dissociation curve
(3) O2 dissociation curve (4) CO2-O2 association curve
Sol. Answer (3)
A graphical representation of relationship between pO2 and percentage saturation of haemoglobin with O2
is known as oxygen dissociation curve or oxygen haemoglobin dissociation curve. It is sigmoid or S-shaped
curve.
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56 Breathing and Exchange of Gases Solution of Assignment (Set-2)
29. High percentage of CO2 is transported in dissolved form as compared to O2. This is because
(1) O2 has high solubility in plasma (2) CO2 has high solubility in plasma
(3) pCO2 is high in blood than pO2 (4) CO2 has low solubility in plasma
Sol. Answer (2)
Ratio of CO2 and O2 solubility in plasma is 25 : 1 (CO2 : O2).
30. Which factor in tissues favours the formation of HCO3– and H+ ions in the blood?
(1) Low pCO2 (2) High pO2 (3) High pCO2 (4) High alkalinity
Sol. Answer (3)
H HCO3
Carbonic anhydrase Carbonic anhydrase
CO2 H2 O H2CO3
2
Zn (Carbonic acid) (Hydrogen ion) (Bicarbonate ion)
31. How much CO2 is delivered to the alveoli by every 100 ml of deoxygenated blood?
(1) 6 ml (2) 4 ml (3) 5 ml (4) 3 ml
Sol. Answer (2)
About 4 ml CO2 is delivered to the alveoli by every 100 ml of deoxygenated blood.
32. Which enzyme is present in RBCs and plasma to catalyse the given reaction?
CO2 + H2O
H2CO3
H + HCO3
+
Carbonic acid
33. A specialised centre known as respiratory rhythm centre regulates respiration. It is located in
(1) Pons (2) Medulla oblongata (3) Cerebrum (4) Cerebellum
Sol. Answer (2)
Respiratory rhythm centre are present in medulla which regulates the normal rhythm of respiration.
34. Which substances when present in high level can activate the chemosensitive area present adjacent to rhythm
centre?
(1) CO2 and O2 (2) HCO3– ions and O2 (3) CO2 and H+ ions (4) H+ and HCO3– ions
Sol. Answer (3)
Chemosensitive area i.e. sensitive for chemicals and is located adjacent to the rhythm centre which contains
chemoreceptors which are sensitive for CO2 and H+ ions. The respiratory centre is stimulated by concentration
or partial pressure of CO2 and H+ ions in blood and body fluids.
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Solution of Assignment (Set-2) Breathing and Exchange of Gases 57
35. Which of the following is an occupational respiratory disease?
(1) Diphtheria (2) Pneumonia (3) Tuberculosis (4) Asbestosis
Sol. Answer (4)
Occupational respiratory disorders occur due to the continuous exposure to harmful substances, gases, fumes
and dust in the environment, where a person works.
Asbestosis caused due to continuonus exposure to asbestos dust at place of work.
Pneumonia : Caused due to the bacteria like Streptococcus pneumoniae and haemophilus influenzae.
Tuberculosis : Caused due to Mycobacterium tuberculosis.
Diphtheria : Caused due to Cornynebacterium diphtheriae.
SECTION - B
Objective Type Questions
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58 Breathing and Exchange of Gases Solution of Assignment (Set-2)
11. What happens to the volume of pulmonary cavity when there is an increase in the volume of thoracic chamber?
(1) It decreases (2) It increases
(3) It remains same (4) First decreases and then increases
Sol. Answer (2)
Increase in the volume of thoracic cavity
Leads to
Air enters from atmosphere to the lungs as it moves from higher pressure to lower pressure
13. What happens when pressure within the pulmonary cavity is higher than the atmospheric pressure?
(1) Inhalation of air (2) Expulsion of air
(3) No inhalation and expulsion of air occurs (4) Lungs inflate and rupture
Sol. Answer (2)
High pressure in pulmonary cavity compared to atmosphere results in explusion of air. Air moves high pressure
to low pressure.
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60 Breathing and Exchange of Gases Solution of Assignment (Set-2)
14. An additional volume of air, a person can inspire by a forceful inspiration is known as
(1) Inspiratory capacity (2) Expiratory capacity
(3) Expiratory reserve volume (4) Inspiratory reserve volume
Sol. Answer (4)
IRV is the additional volume of air a person can inspire by a forceful inspiration.
IRV = 2500 – 300 ml
IC = IRV + TV
3000 – 3500 ml
CO2 0.3 40 45 40 45
17. Which are the three main layers that form the diffusion membrane?
(1) Thin squamous epithelium of alveoli, basement membrane of bronchioles and basement substance
(2) Thin squamous epithelium of alveoli, endothelium of alveolar capillaries and the basement substance
(3) Basement substance, cuboidal epithelium of alveoli and stratified epithelium of bronchiole
(4) Ciliated epithelium of trachea, endothelium of capillaries and basement substance
Sol. Answer (2)
Diffusion of O2 and CO2 depends on the thickness of diffusion membrane.
18. What is the percentage of O2 transported in dissolved form through the plasma?
(1) About 7% (2) About 3% (3) About 20–25% (4) About 15%
Sol. Answer (2)
Oxygen transport by plasma = 3%
Oxygen transport by oxyhaemoglobin = 97%
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Solution of Assignment (Set-2) Breathing and Exchange of Gases 61
19. How many O2 molecules can bind with single molecule of Hb?
(1) 8 (2) 6 (3) 4 (4) 4.5
Sol. Answer (3)
Haemoglobin consists of four polypeptide chain (2and 2) having heme as prosthetic group. Heme is iron
(Fe2+) containing prophyrin ring. One haemoglobin binds four oxygen molecules, one per heme and form
oxyhemoglobin.
Hb + 4O2
Hb(O2)4
2+
Contain Fe with porphyrin ring Include four polypeptide chain (22)
Hb
CO2
HbCO2
(Haemoglobin) (Carbamino haemoglobin)
(Amino group)
21. Which of the following condition is not responsible for shifting the curve towards left?
(1) High pO2 (2) Low pCO2
(3) Low temperature (4) High H+ ion concentration
Sol. Answer (4)
Following are the conditions responsible for shifting the curve towards left :
(a) High pO2
(b) Low pCO2
(c) Less H+ concentration and high pH
(d) Low temperature
All above four conditions are favourable for the association of oxygen with hemoglobin, at alveoli.
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62 Breathing and Exchange of Gases Solution of Assignment (Set-2)
23. Pneumotaxic centre can moderate the functions of respiratory rhythm centre by
(1) Reducing the duration of inspiration
(2) Increasing the duration of inspiration only
(3) First increasing and then reducing the duration of expiration
(4) Increasing the duration of expiration only
Sol. Answer (1)
Pneuomotaxic centre is present in the pons region of hind brain.
It is also known as "switch off point of inspiration" i.e. it reduces the duration of inspiration and alter the
respiratory rate and depth of breathing.
24. A chronic disorder in which alveolar walls are damaged due to excessive cigarette smoking is
(1) Asthma (2) Emphysema (3) Silicosis (4) Bronchitis
Sol. Answer (2)
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Solution of Assignment (Set-2) Breathing and Exchange of Gases 63
28. Skin of man cannot act as respiratory organ because
(1) It is dry (2) It is not thin
(3) It is not permeable to O2 and CO2 (4) All of these
Sol. Answer (4)
Because human skin is dry (does not allow exchange of gases), it is not thin (gases can pass through thin
membrane) and it is impermeable to O2 and CO2).
29. Adam's apple is another name for
(1) Sound box in birds (2) Sound box in man (3) Epiglottis (4) Thyroid cartilage
Sol. Answer (4)
Its shape is like apple. It is hyaline cartilage and more prominent in male.
30. Ring like cartilage of larynx is known as
(1) Thyroid cartilage (2) Arytenoid cartilage (3) Cricoid cartilage (4) Cartilage of Santorini
Sol. Answer (3)
Cricoid cartilage has signet ring-like structure lie below the thyroid cartilage and it is made up of hyaline
cartilage.
31. Which of the following prevents collapsing of trachea?
(1) Muscles (2) Diaphragm (3) Ribs (4) Cartilaginous rings
Sol. Answer (4)
Trachea is lined by C-shaped cartilagenous ring, which prevents the collapsing of trachea.
32. Number of alveoli in the human lungs has been estimated to be approximately
(1) 100 million (2) 300 million (3) 125 million (4) 300 billion
Factual data.
(1) Right lung (2) Left lung (3) Both of these (4) None of these
Both right and left lungs have oblique fissure whereas only right lung also has a horizontal fissure.
34. If a person exhales out forcefully by applying all his efforts. What will the pulmonary volume inhaled by him
immediately under normal condition without applying any extra effort?
After a normal inspiration, the total volume of air a person can expire is known as expiratory capacity
(EC) = TV + ERV
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64 Breathing and Exchange of Gases Solution of Assignment (Set-2)
35. The amount of oxygen transported by one litre of blood under strenous condition is approximately
(1) 5 ml (2) 50 ml (3) 15 ml (4) 150 ml
Sol. Answer (4)
100 ml of blood contains about 20 ml of O2
SECTION - C
Previous Years Questions
1. In man and other mammals, air passes from outside into the lungs through
(1) Nasal cavity, larynx, pharynx, trachea, bronchi, alveoli
(2) Nasal cavity, larynx, pharynx, trachea, bronchioles, alveoli
(3) Nasal cavity, pharynx, larynx, trachea, bronchioles, bronchi, alveoli
(4) Nasal cavity, pharynx, larynx, trachea, bronchi, bronchioles, alveoli
Sol. Answer (4)
External nostils
Respiratory passage :
Nasal chamber
Internal nares
Nasopharynx
Conducting part
Larynx
Trachea
Bronchi
Bronchioles
Alveolar duct
Respiratory/Exchange part
Alveoli
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Solution of Assignment (Set-2) Breathing and Exchange of Gases 65
3. Which one of the following statements is incorrect?
(1) The principle of countercurrent flow facilitates efficient respiration in gills of fishes
(2) The residual air in lungs slightly decreases the efficiency of respiration in mammals
(3) The presence of non-vascular air sacs, increases the efficiency of respiration in birds
(4) In insects, circulating body fluids serve to distribute oxygen to tissues
Sol. Answer (4)
In insects tracheal system serve to distribute oxygen to tissues. Openings of trachae are called spiracles
and present for entry and exist of gases.
4. When a person breathes air through a tube directly into the trachea (tracheotomy) it may lead to serious lung
crushing and infection due to
(1) Cooling effect (2) Drying effect (3) Non filtering effect (4) All of these
Sol. Answer (4)
Because upper respiratory tract helps in filtering the air, bringing air to body temperature and making it moist.
5. Pitch of the voice is lower in males than females as the vocal cords of man are
(1) Thicker and longer (2) Thinner and longer (3) Thicker and shorter (4) Thinner and shorter
Sol. Answer (1)
In males, vocal cord is thicker and longer than females and pitch is affected by this
Male Low pitch and female High pitch
7. Two friends are eating together on a dining table. One of them suddenly starts coughing while swallowing some
food. This coughing would have been due to improper closure of glottis by
(1) Tongue (2) Epiglottis (3) Diaphragm (4) Neck
Sol. Answer (2)
Because epiglottis is the covering or lid of glottis to prevent the entry of food into larynx during swallowing.
8. Which of the following is a possibility for most of us with regards to breathing, by making a conscious effort ?
(1) One can consciously breathe in and breathe out by moving the diaphragm alone, without moving the ribs
at all
(2) The lungs can be made fully empty by forcefully breathing out complete air from them
(3) One can breathe out air totally without oxygen
(4) One can breathe out air through eustachian tubes by closing both the nose and the mouth
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66 Breathing and Exchange of Gases Solution of Assignment (Set-2)
10. In lungs, the air is separated from the venous blood through
(1) Transitional epithelium of alveoli + squamous epithelium of blood vessel
(2) Squamous epithelium of alveoli + endothelium of blood vessel
(3) Squamous epithelium of alveoli + cubical epithelium of blood vessel
(4) Cubical epithelium of alveoli + columnar epithelium of blood vessel
Sol. Answer (2)
Alveolar-capillary membrane or respiratory membrane or diffusion membrane, made up of
(1) Thin squamous epithelium of alveoli
(2) Basement membrane
(3) Endothelial lining of alveolar capillary/blood vessel
11. The figure given below shows a small part of human lung where exchange of gases takes place. In which of
the options given below, the parts labelled A, B, C or D are correctly identified along with its function?
C
A
B
Options
(1) B : Red blood cell - transport of CO2 mainly
(2) C : Arterial capillary - passes oxygen to tissues
(3) A : alveolar cavity - main site of exchange of respiratory gases
(4) D : Capillary wall - exchange of O2 and CO2 takes place here
Sol. Answer (3)
Option (1) is wrong because RBCs are involved in transport of CO2 and O2 both
Option (2) is wrong because C is blood capillary.
Option (4) is wrong because D is basement membrane - substance
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Solution of Assignment (Set-2) Breathing and Exchange of Gases 67
12. Listed below are respiratory capacities and respiratory volumes of a normal human adult along with some values.
Respiratory Values
capacities & volumes
(a) Residual volume 2500 mL
(b) Vital capacity 3500 mL
(c) Inspiratory reserve volume 1200 mL
(d) Inspiratory capacity 4500 mL
Which one of the following is the correct matching of two capacities and volumes?
(1) (a) 4500 mL (b) 3500 mL
(2) (b) 2500 mL (c) 4500 mL
(3) (c) 1200 mL (d) 2500 mL
(4) (d) 3500 mL (a) 1200 mL
Sol. Answer (4)
Residual volume – 1200 ml
Vital capacity – 4500 ml
Inspiratory reserve volume – 2500 ml
Inspiratory capacity – 3500 ml
14. Which of the following volume or capacity of lungs can’t be measured directly by the spirometer?
(1) Residual volume (2) Functional residual capacity
(3) Total capacity (4) All of these
Sol. Answer (4)
Spirometer can measure the volume of air goes inside and outside the lungs. It does not measure the residual
volume of air that remains inside the lungs. So, residual volume, functional residual capacity and total capacity
cannot be measured by spirometer.
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68 Breathing and Exchange of Gases Solution of Assignment (Set-2)
18. A large proportion of oxygen is left unused in the human blood even after its uptake by the body tissues. This O2
(1) Helps in releasing more O2 to the epithelium tissues
(2) Acts as a reserve during muscular exercise
(3) Raises the pCO2 of blood to 75 mm of Hg
(4) Is enough to keep oxyhaemoglobin saturation at 96%
Sol. Answer (2)
Because during exercise, contraction of muscle occurs and for that more energy is required and for energy
oxygen is required.
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Solution of Assignment (Set-2) Breathing and Exchange of Gases 69
20. Although much CO2 is carried in blood, yet blood does not become acidic, because
(1) CO2 is continuously diffused through the tissues and is not allowed to accumulate
(4) CO2 combines with water to form H2CO3 which is neutralized by NaCO3
Sol. Answer (2)
Because blood acts as a buffer, which resists the change in pH of blood, because of bicarbonate ions.
(1) In combination with haemoglobin only (2) Dissolved in blood plasma only
(3) In the form of carbonic acid only (4) As carbaminohaemoglobin and as bicarbonates
Sol. Answer (4)
CO2 transport via plasma = 7%; Bicarbonate = 70%; Haemoglobin = 20–25%
22. Bulk of carbon dioxide (CO2) released from body tissues into the blood is present as
(1) With the help of WBCs and blood serum (2) With the help of platelets and corpuscles
(3) With the help of RBCs and blood plasma (4) With the help of RBCs and WBCs
Sol. Answer (3)
Blood is the medium of transport for O2 and CO2.
24. Blood analysis of a patient reveals an unusually high quantity of carboxyhaemoglobin content. The patient has
been inhaling polluted air containing unusually high content of
(1) Carbon disulphide (2) Chloroform (3) Carbon dioxide (4) Carbon monoxide
Sol. Answer (4)
CO 2
Hb
HbCO 2
(Carbon dioxide) (Carbaminohaemoglobin)
CO
Hb
HbCO
(Carbon monoxide) (Carboxyhaemoglobin)
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70 Breathing and Exchange of Gases Solution of Assignment (Set-2)
26. How carbon monoxide, emitted by automobiles, prevents transport of oxygen to the body tissues?
(1) Cerebellum (2) Medulla oblongata (3) Cerebral peduncle (4) The vagus nerve
Sol. Answer (2)
Respiratory centre is located in medulla oblongata.
(2) Oxygen dissociation curve for foetal haemoglobin is on the left side with respect to maternal haemoglobin
(3) When pneumotaxic centre transmits strong signals then inspiration time becomes shorter
(4) Amount of air left in the lung after normal expiration is termed as residual volume only
Sol. Answer (4)
Amount of air left in the lung after forceful expiration is termed as residual volume.
29. Which of the following reflex is involved to prevent excessive inflation of the lungs?
(1) Stretch reflex (2) Hering-Breuer’s reflex (3) Withdrawal reflex (4) Conditioned reflex
Sol. Answer (2)
Excessive inflation Stretch receptors get activated Cause expiration by sending signal through vagus
nerve to inhibit inspiratory area.
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Solution of Assignment (Set-2) Breathing and Exchange of Gases 71
30. Chemoreceptors present in carotid and aortic arch are very much sensitive to
(1) Increase in pCO2 in arterial blood (2) Increase in pO2 in arterial blood
(3) Decrease in pO2 in venous blood (4) Both (2) & (3)
Sol. Answer (1)
Chemoreceptors present in carotid and aortic are sensitive to CO2 and H+.
31. A person remaining at high altitudes for years becomes more and more acclimatized to the low pO2 by the
following except
(1) Increased pulmonary ventilation (2) Increased in RBCs and haemoglobin concentration
32. If the blood does not deliver adequate O2 to the tissues, it is called
34. People who have migrated from the planes to an area adjoining Rohtang Pass about six months back
(1) Suffer from altitude sickness with symptoms like nausea, fatigue, etc
(2) Have the usual RBC count but their haemoglobin has very high binding affinity to O2
(3) Have more RBCs and their haemoglobin has a lower affinity to O2
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72 Breathing and Exchange of Gases Solution of Assignment (Set-2)
35. Which of the following is the correct statement for respiration in humans?
(1) Workers in grinding and stone-breaking industries may suffer from lung fibrosis
(4) Neural signals from pneumotoxic centre in pons region of brain can increase the duration of inspiration
Sol. Answer (1)
Option (2) is wrong, because ~70% of CO2 is carried by haemoglobin as carbaminohaemoglobin.
Option (3) is wrong, because cigarette smoking lead to damage of alveoli wall.
Option (4) is wrong, because pneumotaxic centre in pons region of brain decrease the duration of inspiration.
39. Number of alveoli in the human lungs has been estimated to be approximately
(1) 100 million (2) 300 million (3) 125 million (4) 300 billion
Sol. Answer (2)
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Solution of Assignment (Set-2) Breathing and Exchange of Gases 73
Sol. Answer (1)
Haldane's effect and Bohr effect complement each other. In the tissue, addition of CO2 to the blood facilitates
unloading of O2 by Bohr effect. In turn, O2 unloading favours uptake of CO2 by Haldane'e effect.
41. Approximately seventy percent of carbon-dioxide absorbed by the blood will be transported to the lungs
(1) As bicarbonate ions
(2) In the form of dissolved gas molecules
(3) By binding to R.B.C.
(4) As carbamino-haemoglobin
Sol. Answer (1)
Nearly 20 – 25 percent of CO2 is transported by RBCs, whereas, 70 percent of it is carried as bicarbonates.
About 7 percent of CO2 is carried as dissolved state in plasma.
SECTION - D
Assertion-Reason Type Questions
1. A : Pneumotaxic centre controls rate of respiration.
R : Primarily it controls switch off point of inspiration.
Sol. Answer (1)
Pneumotaxic centre are switch off centre of inspiration.
2. A : Asthmatic patients use bronchiodilator drugs as well as inhalers for symptomatic relief.
R : Asthma is characterized by the spasm of smooth muscles in the wall of bronchioles due to allergen.
Sol. Answer (1)
Asthma is an allergic reaction.
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74 Breathing and Exchange of Gases Solution of Assignment (Set-2)
6. A : The passage starting with the external nostrils upto the terminal bronchiole constitute the respiratory part.
R : The respiratory part transport the air to the alveoli, clears it from the foreign material, humidified and brings
the air to body temperature.
Sol. Answer (4)
The passage starting with the external nostils upto the terminal bronchiole constitute the conducting part.
7. A : Normal expiration during quiet breathing, unlike inspiration, is a passive process because no muscular
contractions are involved.
R : Normal expiration results from the elastic recoil of the chest wall and lungs.
Sol. Answer (1)
Normal expiration in human is due to relaxation of muscles.
8. A : Human blood always contains more amount of CO2 than blood oxygen.
R : Solubility coefficient of CO2 is more than O2.
Sol. Answer (1)
In 100 ml oxygenated blood, amount of O2 is about 20 ml while of CO2 is about 48 ml.
9. A : When a person starts doing exercise, rate and depth of breathing increase even before these are changes
in pO2, pCO2 or H+ concentration.
R : The main stimulus for these quick changes is due to input from the proprioreceptors, which monitor
movements of joints and muscles.
Sol. Answer (1)
10. A : Emphysema is a chronic obstructive disease of lung, causing irreversible distension and loss of elasticity
of alveoli.
R : Emphysema is preventable if chronic exposure to smoke (cigarette and others) and pollutants is avoided.
Sol. Answer (2)
Emphysema is due to inflation of alveoli.
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