PRX-07034
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IUPAC ime | |
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N-[1-(5-hloro-2,3-dimetoksifenil)etil]-2-metilsulfonil-5-piperazin-1-ilanilin | |
Klinički podaci | |
Način primene | Oralno |
Pravni status | |
Pravni status |
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Identifikatori | |
ATC kod | none |
PubChem | CID 11532574 |
Hemijski podaci | |
Formula | C21H29Cl2N3O4S |
Molarna masa | 490,44 g/mol |
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PRX-07034 je selektivni antagonist 5-HT6 receptora.[1] On utiče na kogniciju, poboljšava memoriju, i potencijalno umanjuje unos hrane i telesnu težinu kod glodara.[1][2][3][4]
Reference
[uredi | uredi izvor]- ^ а б „Science Links Japan | PRX-07034, a Potent and Selective 5-HT6 Receptor Antagonist, Reduces Food Intake and Body Weight in Rats”. Архивирано из оригинала 29. 02. 2012. г.
- ^ Fone KC (2008). „An update on the role of the 5-hydroxytryptamine6 receptor in cognitive function”. Neuropharmacology. 55 (6): 1015—22. PMID 18655798. doi:10.1016/j.neuropharm.2008.06.061.
- ^ „Science Links Japan | Combination of sub-threshold doses of Aricept and PRX-07034, a novel 5-HT6 receptor antagonist, enhances Novel Object Discrimination (NOD) memory”. Архивирано из оригинала 29. 02. 2012. г.
- ^ Halford JC, Harrold JA, Boyland EJ, Lawton CL, Blundell JE (2007). „Serotonergic drugs : effects on appetite expression and use for the treatment of obesity”. Drugs. 67 (1): 27—55. PMID 17209663. Архивирано из оригинала 05. 01. 2013. г. Приступљено 12. 12. 2012.
Spoljašnje veze
[uredi | uredi izvor]- Preclinical Data on Predix Pharmaceuticals' 5-HT6 Antagonist for Obesity and Cognitive...
- Epix’s Experimental Drug PRX-07034 Shows Potential Benefit on Cognition, Obesity
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