Ipsapiron

Ipsapiron
(IUPAC) ime
	9,9-diokso-8-[4-(4-pirimidin-2-ilpiperazin-1-il)butil]-; 9λ6-thia-8-azabiciklo[4.3.0]nona-1,3,5-trien-7-on
Klinički podaci
Identifikatori
CAS broj	95847-70-4
ATC kod	nije dodeljen
PubChem	56971
ChemSpider	51365
UNII	6J9B11MN0K
ChEMBL	CHEMBL8412
Hemijski podaci
Formula	C19H23N5O3S
Mol. masa	401,484 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2 ; Key: TZJUVVIWVWFLCD-UHFFFAOYSA-N
Farmakokinetički podaci
Poluvreme eliminacije	1,3-2,7 sata
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	Nije kontrolisana supstanca
Način primene	Oralno

Ipsapiron je selektivni parcijalni agonist 5-HT_1A receptor iz piperazinske i azapironske hemijske klase.^[5] On ima antidepresivno i anksiolitičko dejstvo.^[5]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ ^5,0 ^5,1 Fanelli RJ, Schuurman T, Glaser T, Traber J (1990). „Ipsapirone: a novel anxiolytic and selective 5-HT1A receptor ligand”. Progress in clinical and biological research 361: 461–7. PMID 1981264.

	Portal Medicina
	Portal Hemija