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New Advances in Keratoplasty
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New Advances in Keratoplasty

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 729

Special Issue Editor

Dr. Cristina Bovone

E-Mail Website
Guest Editor
1. Department of Environmental Sciences and Prevention, University of Ferrara, Ferrara, Italy
2. Department of Ophthalmology, Ospedali Privati Forlì "Villa Igea", Forlì, Italy
Interests: cornea; ophthalmology; keratoplasty; anterior segment surgery

Special Issue Information

Dear Colleagues,

This Special Issue presents an opportunity for ophthalmologists to publish their innovative works focused on the recent advances in keratoplasty surgery. Potential areas of interest include, but are not limited to, the following: lamellar keratoplasty, high-tech intraoperative tools, machine learning and artificial intelligence, and novel surgical techniques. I have the pleasure of inviting you to submit your work for consideration in this Special Issue entitled “New Advances in Keratoplasty". Original research articles (clinical or basic science research), reviews, short communications, and interesting images are welcome. All papers will be fully open access upon publication after peer review.

Dr. Cristina Bovone
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lamellar keratoplasty
  • descemet stripping endothelial keratoplasty (DSAEK)
  • descemet membrane endothelial keratoplasty (DMEK)
  • deep anterior lamellar keratoplasty (DALK)
  • keratoconus
  • corneal dystrophies
  • bullous keratopathy
  • anterior segment OCT

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

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Research

14 pages, 565 KiB  
Article
Assessment of OCT and Angio-OCT Parameters in Keratoconus Patients with and without Penetrating Keratoplasty
by Anna Maria Gadamer, Piotr Miklaszewski, Dominika Janiszewska-Bil, Anita Lyssek-Boroń, Dariusz Dobrowolski, Edward Wylęgała, Beniamin Oskar Grabarek, Aleksandra Kiełbasińska and Katarzyna Krysik
J. Clin. Med. 2024, 13(17), 5111; https://doi.org/10.3390/jcm13175111 - 28 Aug 2024
Viewed by 594
Abstract
Background/Objectives: Keratoconus (KC) is a bilateral eye disease characterized by corneal thinning and cone-like deformation, leading to visual impairment. This study evaluated the radial peripapillary capillaries (RPCs) in keratoconus patients with and without penetrating keratoplasty (PKP) using OCT and angio-OCT, comparing the results [...] Read more.
Background/Objectives: Keratoconus (KC) is a bilateral eye disease characterized by corneal thinning and cone-like deformation, leading to visual impairment. This study evaluated the radial peripapillary capillaries (RPCs) in keratoconus patients with and without penetrating keratoplasty (PKP) using OCT and angio-OCT, comparing the results to a control group. Methods: This retrospective study included 149 eyes, 97 from patients who underwent PKP between January 2018 and February 2023 and 52 from patients who did not undergo PKP. The control group comprised 72 patients (144 eyes) who were healthy volunteers. Measurements included the best corrected visual acuity (BCVA), the intraocular pressure (IOP), slit-lamp biomicroscopy, a fundus examination, and corneal topography, as well as OCT and angio-OCT assessments of the RPCs, retinal nerve fiber layer (RNFL), ganglion cell complex (GCC), and central retinal thickness (CRT). Statistical analyses were performed using Student’s t-test and Pearson’s correlation coefficient. Results: The RNFL was significantly thinner in KC eyes after PKP compared to control eyes (p < 0.001), and the CRT was significantly thicker in KC eyes after PKP compared to control eyes (p = 0.003). However, the GCC was similar across the groups (p = 0.0885). Additionally, RPCs inside the disc were significantly reduced in KC eyes after PKP compared to control eyes (p < 0.0001). A significant positive correlation was found between RPC whole vessel density and RNFL thickness as measured via angio-OCT (r = 0.308, p < 0.0001). Conclusions: This study found that the RPC density inside the disc is significantly reduced in keratoconus patients after penetrating keratoplasty, highlighting RPCs inside the disc as a potential diagnostic tool for further assessment of keratoconus. Full article
(This article belongs to the Special Issue New Advances in Keratoplasty)
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