New Insights into Adipose Tissue Metabolic Function and Dysfunction, 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (20 April 2024) | Viewed by 18461
Special Issue Editors
Interests: pharmacology; natural products; oxidative stress; inflammatory disease; atherosclerosis; metabolic disease; neurodegenerative diseases; autophagy; proliferation and differentiation process
Special Issues, Collections and Topics in MDPI journals
Interests: preclinical pharmacology; inflammation; oxidative stress; natural products; flavonoids; cannabinoids
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Adipose tissue is widely known as an endocrine organ able to modulate systemic metabolism thanks to its effects on energy storage, adipokine production, and adaptive thermogenesis. This endocrine function is carried out in various organs, such as liver, kidney, pancreas, and brain, and thus contributes to homeostatic regulation, energy balance, insulin sensitivity, and vascular–endothelial function.
The dysregulation of the differentiation, metabolism, and endocrine functions of adipocytes leads to adipose tissue dysfunction, which triggers the activation of molecular pathways involved in the physiopathology of overall metabolic diseases, such as obesity, inflammation, insulin resistance, and type 2 diabetes.
New therapeutic approaches targeting adipose tissue and its signaling molecules and heterogeneity could provide potential advances in understanding its pathophysiology and in treating several metabolic syndromes.
The purpose of this Special Issue of the International Journal of Molecular Sciences entitled “New Insights into Adipose Tissue Metabolic Function and Dysfunction” is to compile original research papers and/or relevant updates within the literature on new insights into the pathogenesis, molecular pathways, and beneficial effects of novel and safe treatments for metabolic diseases associated with adipose tissue disfunction.
Dr. Federica Mannino
Dr. Giovanni Pallio
Guest Editors
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Keywords
- inflammation
- browning
- thermogenesis
- adipogenesis
- diabetes
- adipokines
- energy storage
- insulin resistance
- obesity
- lipolysis
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