Topic Editors

Centro de Investigaciones Biológicas del Noroeste (CIBNOR), Baja California Sur 23096, Mexico
Biology, University of Saskatchewan, Saskatoon, SK, Canada

Health Risk Assessment of the Trace and Macro Elements

Abstract submission deadline
closed (30 June 2024)
Manuscript submission deadline
30 August 2024
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10361

Topic Information

Dear Colleagues,

Several trace and macro elements are required to keep organisms alive. However, these can also represent a risk when their concentrations are higher than the levels needed to perform physiological functions. Furthermore, among species, the elements and doses that are essential for living can vary. These facts raise a number of questions: How does the concentration of different chemical elements vary spatially and temporally in the same species? How much of certain elements can a species tolerate? What damage or physiological responses does a species express from a lack or excess of a chemical element? How does an element biomagnify depending on the trophic chain that inhabits a site? Can we identify which elements are essential in some species but not in others? In addition, growing industrial activity needs high metal usage, which has resulted in significant mining around the world in recent years. As a result, the quantities of heavy metals such as arsenic, cadmium, and others in environmental contexts are rapidly growing. The majority of heavy metals accumulate in numerous aquatic pray species, causing death in other aquatic animals, as well as in humans.

This subject also includes study on heavy metal toxicity in environmental species, as well as human investigations. This Topic aims to provide an instrument for the discussion of recent advances in the identification of the factors that influence the accumulation of trace and macro elements among different species. Studies devoted to spatial and temporal analysis of trace and macro elements in marine and terrestrial environments are welcome.

Dr. Lía Celina Méndez-Rodríguez
Dr. Mahesh Rachamalla
Topic Editors

 

Keywords

  • marine environments
  • mineral distribution
  • metal excretion
  • metal physiology
  • pollution
  • contamination
  • marine biogeochemistry

Participating Journals

Journal Name Impact Factor CiteScore Launched Year First Decision (median) APC
Animals
animals
2.7 4.9 2011 16.1 Days CHF 2400 Submit
Environments
environments
3.5 5.7 2014 25.7 Days CHF 1800 Submit
Journal of Marine Science and Engineering
jmse
2.7 4.4 2013 16.9 Days CHF 2600 Submit
Toxics
toxics
3.9 4.5 2013 15.6 Days CHF 2600 Submit
Water
water
3.0 5.8 2009 16.5 Days CHF 2600 Submit

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Published Papers (9 papers)

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18 pages, 3691 KiB  
Article
Variability in Microbial Communities Driven by Particulate Matter on Human Facial Skin
by Kai Fu, Qixing Zhou and Heli Wang
Toxics 2024, 12(7), 497; https://doi.org/10.3390/toxics12070497 - 8 Jul 2024
Viewed by 400
Abstract
Microbial communities are known to play an important role in maintaining ecological balance and can be used as an indicator for assessing environmental pollution. Numerous studies have revealed that air pollution can alter the structure of microbial communities, which may increase health risks. [...] Read more.
Microbial communities are known to play an important role in maintaining ecological balance and can be used as an indicator for assessing environmental pollution. Numerous studies have revealed that air pollution can alter the structure of microbial communities, which may increase health risks. Nevertheless, the relationships between microbial communities and particulate matter (PM) caused by air pollution in terms of health risk assessment are not well understood. This study aimed to validate the influences of PM chemical compositions on microbial communities and assess the associated health risks. Our results, based on similarity analysis, revealed that the stability structure of the microbial communities had a similarity greater than 73%. In addition, the altered richness and diversity of microbial communities were significantly associated with PM chemical compositions. Volatile organic compounds (VOCs) and polycyclic aromatic hydrocarbons (PAHs) exerted a positive influence on microbial communities in different environmental variables. Additionally, a stronger linear correlation was observed between hydroxyl radicals (·OH) and the richness of microbial communities. All estimated health risks from PM chemical compositions, calculated under different environmental variables, significantly exceeded the acceptable level by a factor of more than 49. Cr and 1,2-Dibromoethane displayed dual adverse effects of non-carcinogenic and carcinogenic risks. Overall, the study provides insights into the fundamental mechanisms of the variability in microbial communities driven by PM, which may support the crucial role of PM chemical compositions in the risk of microorganisms in the atmospheric environment. Full article
(This article belongs to the Topic Health Risk Assessment of the Trace and Macro Elements)
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16 pages, 5291 KiB  
Article
Health Risk Assessment of Heavy Metal(loid)s in the Overlying Water of Small Wetlands Based on Monte Carlo Simulation
by Liling Wang, Mamattursun Eziz, Yonglong Hu and Xayida Subi
Toxics 2024, 12(7), 488; https://doi.org/10.3390/toxics12070488 - 3 Jul 2024
Viewed by 453
Abstract
Heavy metal(loid) (HM) contamination is a significant threat to wetland ecosystem. However, contamination risks of HMs in overlying water of small wetlands, which are easily ignored because of their minor occupancy in an overall area, are nearly unknown. A total of 36 water [...] Read more.
Heavy metal(loid) (HM) contamination is a significant threat to wetland ecosystem. However, contamination risks of HMs in overlying water of small wetlands, which are easily ignored because of their minor occupancy in an overall area, are nearly unknown. A total of 36 water samples containing six HMs were collected from the urban and rural small wetlands of Urumqi in China, and the contamination levels and probabilistic health risks caused by HMs were assessed using the Nemerow pollution index (NPI) and the health risk assessment model introduced by the US EPA. The results revealed that the average concentration of Hg in the urban and rural small wetlands surpassed the Class II thresholds of the Environmental Quality Standards for Surface Water (GB 3838-2002) by factors of 3.2 and 5.0 times, respectively. The overall contamination levels of HMs in the small wetlands fall into the high contamination level. Results of a health risk assessment indicated that non-carcinogenic health risk of the investigated HMs are found to be lower than the acceptable range for adults, but higher than the acceptable range for children. Meanwhile, As falls into the low carcinogenic risk level, whereas Cd falls into the very low carcinogenic risk level. Overall, HMs in rural small wetlands showed relatively higher contamination levels and probabilistic health risks than that of urban small wetlands. In addition, As was identified as the dominant health risk factor in the overlying water of small wetlands in the study area. Findings of this study provide scientific support needed for the prevention of HM contamination of small wetlands in arid zones. Full article
(This article belongs to the Topic Health Risk Assessment of the Trace and Macro Elements)
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19 pages, 2904 KiB  
Article
Levels of Potentially Toxic and Essential Elements in Water and Estimation of Human Health Risks in a River Located at the Interface of Brazilian Savanna and Amazon Biomes (Tocantins River)
by Thiago Machado da Silva Acioly, Marcelo Francisco da Silva, Letícia Almeida Barbosa, José Iannacone and Diego Carvalho Viana
Toxics 2024, 12(7), 444; https://doi.org/10.3390/toxics12070444 - 21 Jun 2024
Viewed by 442
Abstract
The Tocantins–Araguaia basin is one of South America’s largest river systems, across three Brazilian states (Maranhão, Tocantins, and Pará), within the Legal Amazon region. Despite draining extensive Cerrado savanna and rainforest ecosystems, it has suffered significant degradation, notably in the past 40 years. [...] Read more.
The Tocantins–Araguaia basin is one of South America’s largest river systems, across three Brazilian states (Maranhão, Tocantins, and Pará), within the Legal Amazon region. Despite draining extensive Cerrado savanna and rainforest ecosystems, it has suffered significant degradation, notably in the past 40 years. Human activities, including agricultural expansion, deforestation, and the introduction of non-native species, have worsened the environmental damage, which is alarming since many residents and villages along the middle Tocantins River rely on it for water supply, recreation, and fishing. This study assessed the concentration of potentially toxic and essential elements in water samples from four sampling sites distributed along the middle Tocantins River. The monitoring occurred throughout 2023, involving the measurement of parameters both on-site and in the laboratory. Water quality and its health implications were evaluated using the Weighted Arithmetic Water Quality Index (WAWQI), the Water Quality Index (WQI), and the health risk assessment index. The levels of aluminum, copper, iron, magnesium, and selenium exceeded legal standards. Seasonal fluctuations indicate a complex dynamic influenced by climatic or seasonal factors, with February showing the highest values. Site P1, located in urban areas, exhibited elevated mean concentrations for conductivity, total dissolved solids (TDS), and chlorophyll, indicating the need for continuous monitoring. The nitrogen concentrations at P1 raise concerns regarding drinking water quality, which is a concern for the region’s residents who use untreated river water. Despite seasonal variations in element concentrations, the overall WAWQI categorized all sections as “Excellent,” and the WQI rated as “Good.” Human health risk assessments detected no risks, but continuous monitoring and interventions are crucial for sustained water quality improvement. Full article
(This article belongs to the Topic Health Risk Assessment of the Trace and Macro Elements)
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17 pages, 8313 KiB  
Article
Migration Patterns and Potential Risk Assessment of Trace Elements in the Soil–Plant System in the Production Area of the Chinese Medicinal Herb Scrophularia ningpoensis Hemsl.
by Yufeng Gong, Wei Ren and Zhenming Zhang
Toxics 2024, 12(5), 355; https://doi.org/10.3390/toxics12050355 - 11 May 2024
Viewed by 744
Abstract
Scrophularia ningpoensis Hemsl. holds a prominent place among Chinese medicinal herbs. Assessing the soil–plant system of its origin is crucial for ensuring medication safety. Although some trace elements are essential for the normal functioning of living organisms, exposure to higher concentrations is harmful [...] Read more.
Scrophularia ningpoensis Hemsl. holds a prominent place among Chinese medicinal herbs. Assessing the soil–plant system of its origin is crucial for ensuring medication safety. Although some trace elements are essential for the normal functioning of living organisms, exposure to higher concentrations is harmful to humans, so in order to assess the possible health risk of trace elements in the soil–plant system of Scrophularia ningpoensis Hemsl. origin for human assessment, we used non-carcinogenic risk (HI) and carcinogenic risk (CR) for their evaluation. In this paper, the following trace elements were studied in the soil–Scrophularia ningpoensis Hemsl. system: manganese (Mn), iron (Fe), cobalt (Co), zinc (Zn), selenium (Se), molybdenum (Mo), arsenic (As) and lead (Pb). Correlation and structural equation analyses showed that the effect of soil in the root zone on the plant was much greater than the effect of soil in the non-root zone on the plant. The single-factor pollution index (Pi) showed that the soil in the production area of Scrophularia ningpoensis Hemsl. was polluted to a certain extent, notably with Pb showing the highest average Pi values of 0.94 and 0.89 in the non-root and root zones, respectively. Additionally, the Nemerow composite pollution indices (PN) for both zones indicated an alert range. Regarding health risks, exposure to soil in the non-root zone posed higher non-carcinogenic risk (HI) and carcinogenic risk (CR) compared to the root zone, although neither zone presented a significant carcinogenic risk. The potential non-carcinogenic risk (HI) and carcinogenic risk (CR) from consuming Scrophularia ningpoensis Hemsl. leaves and stems were more than ten times higher than that of roots. However, the carcinogenic risk (CR) values for both the soil and plant of interest in the soil– Scrophularia ningpoensis Hemsl. system did not exceed 10−4, and therefore no significant carcinogenic risk existed. Full article
(This article belongs to the Topic Health Risk Assessment of the Trace and Macro Elements)
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21 pages, 13023 KiB  
Article
Ecotoxicology of Polymetallic Nodule Seabed Mining: The Effects of Cobalt and Nickel on Phytoplankton Growth and Pigment Concentration
by Rimei Ou, Hao Huang, Xuebao He, Shuangshuang Lin, Danyun Ou, Weiwen Li, Jinli Qiu and Lei Wang
Toxics 2023, 11(12), 1005; https://doi.org/10.3390/toxics11121005 - 8 Dec 2023
Viewed by 1409
Abstract
In order to improve the understanding of the environmental impacts of polymetallic nodule mining, ecotoxicological studies were conducted on the growth of model phytoplankton species Skeletonema costatum and Prorocentrum donghaiense using cobalt and nickel. This study evaluated various physiological and ecological indicators, such [...] Read more.
In order to improve the understanding of the environmental impacts of polymetallic nodule mining, ecotoxicological studies were conducted on the growth of model phytoplankton species Skeletonema costatum and Prorocentrum donghaiense using cobalt and nickel. This study evaluated various physiological and ecological indicators, such as cell proliferation, chlorophyll a, pigments, total protein, and antioxidant enzyme markers. The results show that the introduction of low amounts of cobalt or nickel increased the growth rate of phytoplankton. The phytoplankton benefited from low concentrations of cobalt and nickel stress. The increased protein levels and decreased activity of antioxidant enzymes considerably impacted physiological responses during the promotion of cell abundance. High concentrations of cobalt or nickel resulted in decreased light-absorbing pigments, increased photoprotective pigments, an inactive chlorophyll content, decreased total proteins, and maximal antioxidant enzyme activity in phytoplankton. Throughout the experiment, both the phytoplankton protein and enzyme activity declined with prolonged stress, and the cells underwent age-induced damage. Thus, seabed mining’s repercussions on phytoplankton could result in both short-term growth promotion and long-term damage. These consequences depend on the impurity concentrations infiltrating the water, their duration, and the organism’s physiological responses. Full article
(This article belongs to the Topic Health Risk Assessment of the Trace and Macro Elements)
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17 pages, 2801 KiB  
Article
The Accumulation of Toxic Elements (Pb, Hg, Cd, As, and Cu) in Red Swamp Crayfish (Procambarus clarkii) in Qianjiang and the Associated Risks to Human Health
by Lang Zhang, Ziwei Song, Yuntao Zhou, Shan Zhong, Yali Yu, Ting Liu, Xiaoping Gao, Lekang Li, Chiping Kong, Xinna Wang, Li He and Jinhua Gan
Toxics 2023, 11(7), 635; https://doi.org/10.3390/toxics11070635 - 22 Jul 2023
Cited by 3 | Viewed by 1333
Abstract
Due to rapidly expanding crayfish consumption worldwide, the food safety of red swamp crayfish (Procambarus clarkii) is of great concern. China is the largest consumer and producer of crayfish globally. As of yet, it is unknown whether the main crayfish production [...] Read more.
Due to rapidly expanding crayfish consumption worldwide, the food safety of red swamp crayfish (Procambarus clarkii) is of great concern. China is the largest consumer and producer of crayfish globally. As of yet, it is unknown whether the main crayfish production cities in China are within safe levels of toxic heavy metals and metalloids. For 16 consecutive years, Qianjiang city ranked first in China in processing export volumes of red swamp crayfish. This study presents a comprehensive analysis of the enrichment levels and associated health risks of the species in Qianjiang. In our research, samples of four crayfish tissues, including the head, hepatopancreas, gills, and muscles, were collected from 38 sampling sites distributed in Qianjiang to evaluate the concentration levels of five heavy metals (Pb, Hg, Cd, As, and Cu). The concentration levels of all five metals in muscle did not surpass the national standard. Furthermore, eight significant correlations have been found. For further in-depth assess risk of crayfish in Qianjiang, estimated daily intake (EDI), target hazard quotient (THQ), carcinogenic risk (CR), and estimated maximum allowable consumption rates (CRmm) were evaluated in the abdomen muscle and hepatopancreas. The THQ values for each metal were found to be less than 1, while the CR values were below 10–6. Additionally, the CRmm for adults was determined to be 17.2 meals per month. These findings, based on the analysis of five metallic elements included in this study, suggest that the consumption of crayfish abdomen muscle in Qianjiang does not pose any significant health risks. However, it is noteworthy that certain regions exhibit elevated levels of arsenic in the hepatopancreas, surpassing the national standard, thereby rendering them unsuitable for excessive consumption. In general, the findings can be used to provide guidance for safe dietary practices in China. Full article
(This article belongs to the Topic Health Risk Assessment of the Trace and Macro Elements)
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17 pages, 9013 KiB  
Article
Accumulation Pattern and Risk Assessment of Potentially Toxic Elements in Permafrost-Affected Agricultural Soils in Northeast China
by Junbo Yu, Chuanfang Zhou, Ke Yang, Qifa Sun, Qipeng Zhang, Zhiwei Yang and Yangyang Chen
Toxics 2023, 11(7), 632; https://doi.org/10.3390/toxics11070632 - 21 Jul 2023
Cited by 1 | Viewed by 948
Abstract
The accumulation of potentially toxic elements (PTEs) in agricultural soils is of particular concern in China, while its status, ecological risks, and human health hazards have been little studied in the permafrost areas of Northeast China. In this study, 75 agricultural soil samples [...] Read more.
The accumulation of potentially toxic elements (PTEs) in agricultural soils is of particular concern in China, while its status, ecological risks, and human health hazards have been little studied in the permafrost areas of Northeast China. In this study, 75 agricultural soil samples (0–20 cm) were collected from the Arctic Village, Mo’he City, in the northernmost part of China. The average concentration (mean ± standard deviation) of As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn were 12.11 ± 3.66 mg/kg, 0.11 ± 0.08 mg/kg, 52.50 ± 8.83 mg/kg, 12.08 ± 5.12 mg/kg, 0.05 ± 0.02 mg/kg, 14.90 ± 5.35 mg/kg, 22.38 ± 3.04 mg/kg, and 68.07 ± 22.71 mg/kg, respectively. Correlation analysis, cluster analysis, and principal component analysis indicated that As, Cu, Ni, and Zn likely originated from geogenic processes, Hg and Pb from long-range atmospheric transport, Cd from planting activities, and Cr from Holocene alluvium. The geo-accumulation index and enrichment factor showed that As, Cd, Hg, and Zn are enriched in soils. The Nemerow pollution index showed that 66.67%, 24%, and 1.33% of soil samples were in slight, moderate, and heavy pollution levels, respectively, with Hg being the most important element affecting the comprehensive pollution index. The potential ecological risk index showed that 48.00% and 1.33% of soil samples were in the moderate ecological risk and high potential ecological risk levels, respectively. The non-carcinogenic and carcinogenic human health risk index for adults and children were both less than 1, which was within the acceptable range. This study revealed the accumulation pattern of PTEs in agricultural soils of permafrost regions and provided a scientific basis for research on ecological security and human health. Full article
(This article belongs to the Topic Health Risk Assessment of the Trace and Macro Elements)
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20 pages, 4484 KiB  
Article
Spatial and Multivariate Statistical Analyses of Human Health Risk Associated with the Consumption of Heavy Metals in Groundwater of Monterrey Metropolitan Area, Mexico
by Edrick Ramos, Raja Karim Bux, Dora Ileana Medina, Héctor Barrios-Piña and Jürgen Mahlknecht
Water 2023, 15(6), 1243; https://doi.org/10.3390/w15061243 - 22 Mar 2023
Cited by 8 | Viewed by 2067
Abstract
Groundwater is the main source of drinking water supply in most urban environments around the world. The content of potentially toxic elements is increasing in many groundwater systems owing to inadequate groundwater recharge, aquifer overexploitation, natural source release, or various anthropogenic activities that [...] Read more.
Groundwater is the main source of drinking water supply in most urban environments around the world. The content of potentially toxic elements is increasing in many groundwater systems owing to inadequate groundwater recharge, aquifer overexploitation, natural source release, or various anthropogenic activities that lead to groundwater quality degradation. The ingestion of groundwater contaminated with potentially toxic elements has been reported to have harmful health effects. This study aimed to assess the presence of several potentially toxic elements (Al, As, B, Cr, Cu, Fe, Mn, and Zn) in groundwater of the Monterrey metropolitan area in Northern Mexico and the carcinogenic and noncarcinogenic human health risks associated with exposure. Multivariate statistics and geospatial analysis were applied to identify the causative determinants that modify the groundwater quality along the metropolitan area. Mean concentrations of trace metals remained below drinking water standards and World Health Organization guidelines. The risk of harmful effects on human health due to ingestion of all eight metal(loid)s in groundwater was assessed as 2.52 × 10−2 for adults and 2.16 × 10−2 for children, which can be considered as negligible chronic risk and a very low cancer risk. However, the risks of oral consumption of Cr being carcinogenic to children and adults were 7.9 × 10−3 and 9.2 × 10−4, respectively. As these values exceeded the target risk of 1 × 10−4, it can thus be considered “unacceptable”. Full article
(This article belongs to the Topic Health Risk Assessment of the Trace and Macro Elements)
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15 pages, 2323 KiB  
Article
Spatial and Temporal Variability of Trace and Macro Elements in the Red Crab Pleuroncodes planipes in the Pacific Coast of the Baja California Peninsula, Mexico
by Juan Antonio De Anda-Montañez, Tania Zenteno-Savín, Eduardo F. Balart, Baudilio Acosta-Vargas, Ramón Gaxiola-Robles and Lia Celina Méndez-Rodríguez
Animals 2023, 13(5), 822; https://doi.org/10.3390/ani13050822 - 24 Feb 2023
Viewed by 1558
Abstract
The red crab, Pleuroncodes planipes, is a decapod crustacean abundant off the Pacific coast of the Baja California Peninsula. This species is caught and used in preparing animal feed, such as flour, particularly for aquaculture. Levels of calcium (Ca), cadmium (Cd), copper [...] Read more.
The red crab, Pleuroncodes planipes, is a decapod crustacean abundant off the Pacific coast of the Baja California Peninsula. This species is caught and used in preparing animal feed, such as flour, particularly for aquaculture. Levels of calcium (Ca), cadmium (Cd), copper (Cu), iron (Fe), lead (Pb), magnesium (Mg), manganese (Mn), nickel (Ni), phosphorus (P), and zinc (Zn) were measured in red crabs collected from three geographic zones during three cruises in different seasons. Significant differences were found in the levels of Ca, Cd, Cu, Fe, Mg, Ni, P, and Zn between the two El Niño years (cruises C1 and C3, based on a threshold of ±0.5 °C for the Oceanic Niño Index). The highest concentrations of most elements were observed in the south of the Baja California Peninsula, a highly productive area influenced by upwelling events. Our findings suggest that while environmental temperature plays a central role in the benthic or pelagic distribution of red crabs, their content and variability of trace and macro elements appear to be associated with the presence of oceanic conditions, such as upwelling and potential changes in the composition of their diet associated with the depth in which these crustaceans are collected. Full article
(This article belongs to the Topic Health Risk Assessment of the Trace and Macro Elements)
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