Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q24791909)
Watch
English
Pten dose dictates cancer progression in the prostate
scientific article
In more languages
edit
Statements
instance of
scholarly article
0 references
title
Pten dose dictates cancer progression in the prostate
(English)
0 references
author
Carlos Cordon-Cardo
series ordinal
11
0 references
Pier Paolo Pandolfi
series ordinal
12
0 references
Terry Van Dyke
series ordinal
10
0 references
Antonio Di Cristofano
object named as
Antonio Di Cristofano
series ordinal
5
0 references
Lloyd Trotman
series ordinal
1
object named as
Lloyd C Trotman
0 references
Zohar A Dotan
series ordinal
3
object named as
Zohar A Dotan
0 references
Masaru Niki
series ordinal
2
object named as
Masaru Niki
0 references
Jason A Koutcher
series ordinal
4
object named as
Jason A Koutcher
0 references
author name string
Andrew Xiao
series ordinal
6
0 references
Alan S Khoo
series ordinal
7
0 references
Pradip Roy-Burman
series ordinal
8
0 references
Norman M Greenberg
series ordinal
9
0 references
language of work or name
English
0 references
publication date
December 2003
0 references
published in
PLOS Biology
0 references
volume
1
0 references
issue
3
0 references
page(s)
E59
0 references
cites work
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
Mutation and cancer: statistical study of retinoblastoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
Pten is essential for embryonic development and tumour suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
Efficient in vivo manipulation of mouse genomic sequences at the zygote stage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
Regulation of translation initiation by FRAP/mTOR
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
7 April 2017
HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
PTEN function in mammalian cell size regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
Prostatic intraepithelial neoplasia in genetically engineered mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
The multiple roles of PTEN in tumor suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 September 2017
Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=270016
retrieved
28 November 2018
Impaired Fas response and autoimmunity in Pten+/- mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14691534
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Prostate specific expression of Cre recombinase in transgenic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14691534
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14691534
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14691534
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14691534
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regulation of prostatic genes: role of androgens and zinc in gene expression
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14691534
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Distinct altered patterns of p27KIP1 gene expression in benign prostatic hyperplasia and prostatic carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14691534
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14691534
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1371/JOURNAL.PBIO.0000059
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4026054
OpenCitations bibliographic resource ID
4026054
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4026054
PMC publication ID
270016
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4026054
PubMed publication ID
14691534
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4026054
ResearchGate publication ID
8944931
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit