(Q34942330)

5 August 2017

1 reference

title

PTEN function in mammalian cell size regulation (English)

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5 August 2017

Vuk Stambolic

2

0 references

author name string

Stéphanie Backman

series ordinal

1

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5 August 2017

Tak Mak

series ordinal

3

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5 August 2017

publication date

1 October 2002

1 reference

Current Opinion in Neurobiology

5 August 2017

published in

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5 August 2017

volume

12

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5 August 2017

issue

5

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5 August 2017

page(s)

516-522

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

5 August 2017

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7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

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Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

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Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

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7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

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7 January 2021

Modulation of cellular apoptotic potential: contributions to oncogenesis

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7 January 2021

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Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

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7 January 2021

Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways

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7 January 2021

Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor

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7 January 2021

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

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7 January 2021

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

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7 January 2021

The conserved PI3'K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila

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7 January 2021

c-Myc regulates mammalian body size by controlling cell number but not cell size

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7 January 2021

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

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7 January 2021

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

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7 January 2021

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7 January 2021

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo

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7 January 2021

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

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7 January 2021

Genetic control of cell size

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7 January 2021

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K.

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7 January 2021

Diversification of cell cycle controls in developing embryos

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7 January 2021

Cell cycle regulators in neural stem cells and postmitotic neurons

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7 January 2021

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

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7 January 2021

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

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7 January 2021

A role for nuclear PTEN in neuronal differentiation.

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7 January 2021

Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway

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7 January 2021

gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle

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7 January 2021

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation

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7 January 2021

Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Germline and germline mosaic PTEN mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arteriovenous malformations and lipomatosis

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7 January 2021

Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes

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7 January 2021

Drosophila S6 kinase: a regulator of cell size

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7 January 2021

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7 January 2021

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7 January 2021

The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila

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7 January 2021

Mammalian TOR: a homeostatic ATP sensor

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7 January 2021

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7 January 2021

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

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7 January 2021

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

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7 January 2021

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7 January 2021

PDK1 regulates growth through Akt and S6K in Drosophila

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7 January 2021

Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB.

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7 January 2021

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

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7 January 2021

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

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7 January 2021

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7 January 2021

10.1016/S0959-4388(02)00354-9

Identifiers

DOI

1 reference

5 August 2017

1 reference