(Q28203143)

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Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

scientific article (publication date: October 2002)

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Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer (English)

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phosphorylation

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object named as

Alfredo Fusco

11

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Gennaro Chiappetta

8

object named as

Gennaro Chiappetta

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Massimo Santoro

12

object named as

Massimo Santoro

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author name string

Giuseppe Viglietto

1

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Maria Letizia Motti

2

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Paola Bruni

3

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Rosa Marina Melillo

4

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Amelia D'Alessio

5

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Daniela Califano

6

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Floriana Vinci

7

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Philip Tsichlis

9

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Alfonso Bellacosa

10

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language of work or name

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publication date

October 2002

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Nature Medicine

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8

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10

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1136-44

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The Hallmarks of Cancer

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https://api.crossref.org/works/10.1038/NM762

21 April 2017

p16(MTS-1/CDKN2/INK4a) in cancer progression

1 reference

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Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

1 reference

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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Regulation of cell death protease caspase-9 by phosphorylation

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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Direct control of the Forkhead transcription factor AFX by protein kinase B

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Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

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PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1

1 reference

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Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1 reference

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21 April 2017

Principles of CDK regulation

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21 April 2017

Cellular survival: a play in three Akts

1 reference

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Cancer cell cycles

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Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

1 reference

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CDK inhibitors: positive and negative regulators of G1-phase progression

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Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions

1 reference

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Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

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Overexpressed cyclin D3 contributes to retaining the growth inhibitor p27 in the cytoplasm of thyroid tumor cells

1 reference

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Multiple functions of p27(Kip1) and its alterations in tumor cells: a review

1 reference

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The murine gene p27Kip1 is haplo-insufficient for tumour suppression

1 reference

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7 January 2021

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Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

1 reference

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7 January 2021

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Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

1 reference

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7 January 2021

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Abnormal integrin-mediated regulation of chronic myelogenous leukemia CD34+ cell proliferation: BCR/ABL up-regulates the cyclin-dependent kinase inhibitor, p27Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of the cyclin-dependent kinase inhibitor p27 upon loss of the tuberous sclerosis complex gene-2

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21Cip1 and p27Kip1 in anchorage-independent cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

AKT plays a central role in tumorigenesis

1 reference

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inferred from DOI database lookup

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The multiple roles of PTEN in tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FNM762

7 January 2021

based on heuristic

inferred from DOI database lookup

p27 Kip1 inhibits HER2/neu-mediated cell growth and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FNM762

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms and consequences of activation of protein kinase B/Akt

1 reference

https://api.crossref.org/works/10.1038%2FNM762

7 January 2021

based on heuristic

inferred from DOI database lookup

AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of TGF-beta growth inhibition by oncogenic ras is linked to p27Kip1 mislocalization

1 reference

https://api.crossref.org/works/10.1038%2FNM762

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt activation by growth factors is a multiple-step process: the role of the PH domain

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation.

1 reference

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7 January 2021

based on heuristic

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Consolidated OpenCitations Corpus – April 2017

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release_o546d7dmw5dx7myztjbsm7frpe

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https://api.fatcat.wiki/v0/release/o546d7dmw5dx7myztjbsm7frpe

24 November 2022

based on heuristic

mapped directly with Wikidata item

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

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PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

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