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TJAP1

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TJAP1
Identifikatori
AliasiTJAP1
Vanjski ID-jeviOMIM: 612658 MGI: 1921344 HomoloGene: 12534 GeneCards: TJAP1
Lokacija gena (čovjek)
Hromosom 6 (čovjek)
Hrom.Hromosom 6 (čovjek)[1]
Hromosom 6 (čovjek)
Genomska lokacija za TJAP1
Genomska lokacija za TJAP1
Bend6p21.1Početak43,477,523 bp[1]
Kraj43,506,556 bp[1]
Lokacija gena (miš)
Hromosom 17 (miš)
Hrom.Hromosom 17 (miš)[2]
Hromosom 17 (miš)
Genomska lokacija za TJAP1
Genomska lokacija za TJAP1
Bend17|17 CPočetak46,568,777 bp[2]
Kraj46,593,952 bp[2]
Obrazac RNK ekspresije


Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
Ćelijska komponenta citoplazma
međućelijske veze
endozom
trans-Golđijeva mreža
ćelijska membrana
bicellular tight junction
Golđijev aparat
Biološki proces Golgi organization
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)
NM_001146016
NM_001146017
NM_001146018
NM_001146019
NM_001146020

NM_080604
NM_001350561
NM_001350562
NM_001350563
NM_001350564
NM_001350565
NM_001350566
NM_001350567
NM_001350568
NM_001350569
NM_001350570
NM_001394538
NM_001394539
NM_001394540
NM_001394541
NM_001394542
NM_001394543
NM_001394544
NM_001394545

NM_001252473
NM_001252474
NM_001252475
NM_028751

RefSeq (bjelančevina)
NP_001139488
NP_001139489
NP_001139490
NP_001139491
NP_001139492

NP_542171
NP_001337490
NP_001337491
NP_001337492
NP_001337493
NP_001337494
NP_001337495
NP_001337496
NP_001337497
NP_001337498
NP_001337499

NP_001239402
NP_001239403
NP_001239404
NP_083027

Lokacija (UCSC)Chr 6: 43.48 – 43.51 MbChr 17: 46.57 – 46.59 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Uskovezno pridruženi protein 1 jest protein koji je kod ljudi kodiran genom TJAP1.[5][6]

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 557 aminokiselina, а molekulska težina 61.821 Da.[7]

1020304050
MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENE
ELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQN
SYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNK
LLDAKNTINKLEELNERYRLDCNLAVQLLKCNKSHFRNHKFADLPCELQD
MVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPESLLLNSAQSG
SAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS
PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNC
TYATRQAISLSLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAP
ASSASSEEDLLVSWQRAFVDRTPPPAAVAQRTAFGRDALPELQRHFAHSP
ADRDEVVQAPSARPEESELLLPTEPDSGFPREEEELNLPISPEEERQSLL
PINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHLHRKDSLTQAQ
EQGNLLN

Interakcije

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Pokazano je da TJAP1 ima interakcije sa DLG1.[5]

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000137221 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000012296 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Kawabe H, Nakanishi H, Asada M, Fukuhara A, Morimoto K, Takeuchi M, Takai Y (Dec 2001). "Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells". J Biol Chem. 276 (51): 48350–5. doi:10.1074/jbc.M107335200. PMID 11602598.
  6. ^ "Entrez Gene: TJAP1 tight junction associated protein 1 (peripheral)".
  7. ^ "UniProt, Q5JTD0" (jezik: engleski). Pristupljeno 5. 10. 2021.

Dopunska literatura

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