CASZ1
Izgled
Pretpostavljeni protein vezan za preživljavanje jest protein koji je kod ljudi kodiran genom CASZ1 sa hromosoma 1.[5][6]
Amiokiselininska sekvenca
[uredi | uredi izvor]Dužina polipeptidnog lanca je 1.759 aminokiselina, a molekulska težina Da. 190 069[7]
10 | 20 | 30 | 40 | 50 | ||||
---|---|---|---|---|---|---|---|---|
MDLGTAEGTR | CTDPPAGKPA | MAPKRKGGLK | LNAICAKLSR | QVVVEKRADA | ||||
GSHTEGSPSQ | PRDQERSGPE | SGAARAPRSE | EDKRRAVIEK | WVNGEYSEEP | ||||
APTPVLGRIA | REGLELPPEG | VYMVQPQGCS | DEEDHAEEPS | KDGGALEEKD | ||||
SDGAASKEDS | GPSTRQASGE | ASSLRDYAAS | TMTEFLGMFG | YDDQNTRDEL | ||||
ARKISFEKLH | AGSTPEAATS | SMLPTSEDTL | SKRARFSKYE | EYIRKLKAGE | ||||
QLSWPAPSTK | TEERVGKEVV | GTLPGLRLPS | STAHLETKAT | ILPLPSHSSV | ||||
QMQNLVARAS | KYDFFIQKLK | TGENLRPQNG | STYKKPSKYD | LENVKYLHLF | ||||
KPGEGSPDMG | GAIAFKTGKV | GRPSKYDVRG | IQKPGPAKVP | PTPSLAPAPL | ||||
ASVPSAPSAP | GPGPEPPASL | SFNTPEYLKS | TFSKTDSITT | GTVSTVKNGL | ||||
PTDKPAVTED | VNIYQKYIAR | FSGSQHCGHI | HCAYQYREHY | HCLDPECNYQ | ||||
RFTSKQDVIR | HYNMHKKRDN | SLQHGFMRFS | PLDDCSVYYH | GCHLNGKSTH | ||||
YHCMQVGCNK | VYTSTSDVMT | HENFHKKNTQ | LINDGFQRFR | ATEDCGTADC | ||||
QFYGQKTTHF | HCRRPGCTFT | FKNKCDIEKH | KSYHIKDDAY | AKDGFKKFYK | ||||
YEECKYEGCV | YSKATNHFHC | IRAGCGFTFT | STSQMTSHKR | KHERRHIRSS | ||||
GALGLPPSLL | GAKDTEHEES | SNDDLVDFSA | LSSKNSSLSA | SPTSQQSSAS | ||||
LAAATAATEA | GPSATKPPNS | KISGLLPQGL | PGSIPLALAL | SNSGLPTPTP | ||||
YFPILAGRGS | TSLPVGTPSL | LGAVSSGSAA | SATPDTPTLV | ASGAGDSAPV | ||||
AAASVPAPPA | SIMERISASK | GLISPMMARL | AAAALKPSAT | FDPGSGQQVT | ||||
PARFPPAQVK | PEPGESTGAP | GPHEASQDRS | LDLTVKEPSN | ESNGHAVPAN | ||||
SSLLSSLMNK | MSQGNPGLGS | LLNIKAEAEG | SPAAEPSPFL | GKAVKALVQE | ||||
KLAEPWKVYL | RRFGTKDFCD | GQCDFLHKAH | FHCVVEECGA | LFSTLDGAIK | ||||
HANFHFRTEG | GAAKGNTEAA | FPASAAETKP | PMAPSSPPVP | PVTTATVSSL | ||||
EGPAPSPASV | PSTPTLLAWK | QLASTIPQMP | QIPASVPHLP | ASPLATTSLE | ||||
NAKPQVKPGF | LQFQENDPCL | ATDCKYANKF | HFHCLFGNCK | YVCKTSGKAE | ||||
SHCLDHINPN | NNLVNVRDQF | AYYSLQCLCP | NQHCEFRMRG | HYHCLRTGCY | ||||
FVTNITTKLP | WHIKKHEKAE | RRAANGFKYF | TKREECGRLG | CKYNQVNSHF | ||||
HCIREGCQFS | FLLKHQMTSH | ARKHMRRMLG | KNFDRVPPSQ | GPPGLMDAET | ||||
DECMDYTGCS | PGAMSSESST | MDRSCSSTPV | GNESTAAGNT | ISMPTASGAK | ||||
KRFWIIEDMS | PFGKRRKTAS | SRKMLDEGMM | LEGFRRFDLY | EDCKDAACQF | ||||
SLKVTHYHCT | RENCGYKFCG | RTHMYKHAQH | HDRVDNLVLD | DFKRFKASLS | ||||
CHFADCPFSG | TSTHFHCLRC | RFRCTDSTKV | TAHRKHHGKQ | DVISAAGFCQ | ||||
FSSSADCAVP | DCKYKLKCSH | FHCTFPGCRH | TVVGMSQMDS | HKRKHEKQER | ||||
GEPAAEGPAP | GPPISLDGSL | SLGAEPGSLL | FLQSAAAGLG | LALGDAGDPG | ||||
PPDAAAPGPR | EGAAAAAAAA | GESSQEDEEE | ELELPEEEAE | DDEDEDDDED | ||||
DDDEDDDEDD | DDEDLRTDSE | ESLPEAAAEA | AGAGARTPAL | AALAALGAPG | ||||
PAPTAASSP |
Reference
[uredi | uredi izvor]- ^ a b c GRCh38: Ensembl release 89: ENSG00000130940 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028977 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Liu Z, Yang X, Tan F, Cullion K, Thiele CJ (maj 2006). "Molecular cloning and characterization of human Castor, a novel human gene upregulated during cell differentiation". Biochem Biophys Res Commun. 344 (3): 834–44. doi:10.1016/j.bbrc.2006.03.207. PMID 16631614.
- ^ "Entrez Gene: CASZ1 castor zinc finger 1".
- ^ "UniProt, Q86V15" (jezik: engleski). Pristupljeno 22. 11. 2021.
Dopunska literatura
[uredi | uredi izvor]- Fernandez F, Curtain RP, Colson NJ, et al. (2007). "Association analysis of chromosome 1 migraine candidate genes". BMC Med. Genet. 8: 57. doi:10.1186/1471-2350-8-57. PMC 2034370. PMID 17727731.
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
- Yuan ZR, Wang R, Solomon J, et al. (2006). "Identification and characterization of survival-related gene, a novel cell survival gene controlling apoptosis and tumorigenesis". Cancer Res. 65 (23): 10716–24. doi:10.1158/0008-5472.CAN-05-2176. PMID 16322216.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Vanjski linkovi
[uredi | uredi izvor]- Lokacija ljudskog genoma CASZ1 i stranica sa detaljima o genu CASZ1 u UCSC Genome Browseru.