2-硝基咪唑
外观
2-硝基咪唑 | |
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英文名 | 2-nitroimidazole |
识别 | |
CAS号 | 527-73-1 ![]() |
SMILES |
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性质 | |
化学式 | C3H3N3O2 |
摩尔质量 | 113.07 g·mol−1 |
熔点 | 287 °C(分解)[1] |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
2-硝基咪唑是一种有机化合物,为硝基咪唑的同分异构体之一,化学式为C3H3N3O2。它可以2-溴咪唑或2-氨基咪唑为原料制得。[2][3]它可以和氢氧化钾反应,生成2-硝基咪唑钾。[4]它和N-溴代丁二酰亚胺在DMF中反应,可以得到4,5-二溴-2-硝基咪唑。[5]
参考文献
[编辑]- ^ "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US). Retrieved from SciFinder. [2020-11-18]
- ^ 吴义杰, 朱勤. 2-硝基咪唑的制备. 中国医药工业杂志, 1994, 025(004):181-181.
- ^ 熊绪杰. 2-硝基咪唑的制备方法. 2020. CN 111018788 A.
- ^ Caterina F. Ramogida, Jinhe Pan, Cara L. Ferreira, Brian O. Patrick, Karla Rebullar, Donald T. T. Yapp, Kuo-Shyan Lin, Michael J. Adam, Chris Orvig. Nitroimidazole-Containing H 2 dedpa and H 2 CHX dedpa Derivatives as Potential PET Imaging Agents of Hypoxia with 68 Ga. Inorganic Chemistry. 2015-05-18, 54 (10): 4953–4965 [2020-11-18]. ISSN 0020-1669. doi:10.1021/acs.inorgchem.5b00554 (英语).
- ^ Palmer, Brian D.; Denny, William A. Synthesis and reactions of brominated 2-nitroimidazoles. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989. 1: 95-99. ISSN: 0300-922X.