Mitochondrial dysfunction in Parkinson's disease (Q80228162)

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29 December 2019

review article

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title

Mitochondrial dysfunction in Parkinson's disease (English)

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29 December 2019

1 reference

1

A H V Schapira

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29 December 2019

publication date

27 April 2007

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Cell Death & Differentiation

29 December 2019

published in

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29 December 2019

volume

14

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29 December 2019

issue

7

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29 December 2019

page(s)

1261-1266

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Mitochondrial complex I deficiency in Parkinson's disease

29 December 2019

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Complex I, iron, and ferritin in Parkinson's disease substantia nigra

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Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease

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7 January 2021

L-dihydroxyphenylalanine and complex I deficiency in Parkinson's disease brain

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Mitochondrial respiratory chain function in multiple system atrophy

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7 January 2021

Evidence for mitochondrial dysfunction in Parkinson's disease--a critical appraisal

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7 January 2021

A 31P magnetic resonance spectroscopy study of mitochondrial function in skeletal muscle of patients with Parkinson's disease

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Generalized mitochondrial dysfunction in Parkinson's disease detected by magnetic resonance spectroscopy of muscle

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Abnormalities of the electron transport chain in idiopathic Parkinson's disease

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7 January 2021

Platelet mitochondrial function in Parkinson's disease. The Royal Kings and Queens Parkinson Disease Research Group

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7 January 2021

Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease

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7 January 2021

Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence

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7 January 2021

Mitochondrial DNA analysis in Parkinson's disease

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7 January 2021

Mitochondrial DNA in postmortem brain from patients with Parkinson's disease

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7 January 2021

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons

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7 January 2021

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

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7 January 2021

Distinct clustering of point mutations in mitochondrial DNA among patients with mitochondrial encephalomyopathies and with Parkinson's disease

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7 January 2021

Point mutations of mitochondrial genome in Parkinson's disease

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7 January 2021

Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients.

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7 January 2021

Absence of the mitochondrial A7237T mutation in Parkinson's disease

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7 January 2021

Novel mitochondrial DNA mutations in Parkinson's disease

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7 January 2021

Sequence analysis of the entire mitochondrial genome in Parkinson's disease

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7 January 2021

Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson Disease

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7 January 2021

Mitochondrial DNA haplogroup cluster UKJT reduces the risk of PD.

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7 January 2021

mt4216C variant in linkage with the mtDNA TJ cluster may confer a susceptibility to mitochondrial dysfunction resulting in an increased risk of Parkinson's disease in the Irish

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7 January 2021

Origin and functional consequences of the complex I defect in Parkinson's disease

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7 January 2021

Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease

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7 January 2021

Mitochondrial ND5 mutations in idiopathic Parkinson's disease

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7 January 2021

Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study.

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7 January 2021

A novel polymerase gamma mutation in a family with ophthalmoplegia, neuropathy, and Parkinsonism

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7 January 2021

Analysis of the trinucleotide CAG repeat from the DNA polymerase gamma gene (POLG) in patients with Parkinson's disease.

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7 January 2021

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

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7 January 2021

Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway.

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7 January 2021

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

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7 January 2021

PINK1 mutations are associated with sporadic early-onset parkinsonism

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7 January 2021

Novel PINK1 mutations in early-onset parkinsonism

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7 January 2021

Homozygous PINK1 C-terminus mutation causing early-onset parkinsonism

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7 January 2021

Signaling--2000 and beyond

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7 January 2021

The origins of protein phosphorylation

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7 January 2021

The protein kinase complement of the human genome

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7 January 2021

Identification of 14 new phosphoproteins involved in important plant mitochondrial processes

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7 January 2021

Proteome analysis reveals phosphorylation of ATP synthase beta -subunit in human skeletal muscle and proteins with potential roles in type 2 diabetes.

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7 January 2021

Analysis of steady-state protein phosphorylation in mitochondria using a novel fluorescent phosphosensor dye.

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7 January 2021

The phosphorylation of subunits of complex I from bovine heart mitochondria.

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7 January 2021

Focused proteomics: monoclonal antibody-based isolation of the oxidative phosphorylation machinery and detection of phosphoproteins using a fluorescent phosphoprotein gel stain

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7 January 2021

Characterization of dynamic and steady-state protein phosphorylation using a fluorescent phosphoprotein gel stain and mass spectrometry

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7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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7 January 2021

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

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7 January 2021

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

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7 January 2021

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

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7 January 2021

Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.

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7 January 2021

Mitochondria and dopamine: new insights into recessive parkinsonism

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7 January 2021

Parkin enhances mitochondrial biogenesis in proliferating cells

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7 January 2021

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

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7 January 2021

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

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7 January 2021

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

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7 January 2021

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

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7 January 2021

L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system

1 reference

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7 January 2021

Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition

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7 January 2021

Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system

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7 January 2021

The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis

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7 January 2021

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

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7 January 2021

Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice

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7 January 2021

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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7 January 2021

Interactions of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine with monoamine oxidases

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7 January 2021

Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons

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7 January 2021

Production and disposition of 1-methyl-4-phenylpyridinium in primary cultures of mouse astrocytes

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7 January 2021

Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes

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7 January 2021

Uptake of MPP(+) by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP.

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7 January 2021

Suppression of MPTP-induced dopaminergic neurotoxicity in mice by nomifensine and L-DOPA.

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7 January 2021

Protection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism by the catecholamine uptake inhibitor nomifensine: behavioral analysis in monkeys with partial striatal dopamine depletions

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7 January 2021

Characterization of the binding of N-methyl-4-phenylpyridine, the toxic metabolite of the parkinsonian neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, to neuromelanin

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7 January 2021

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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7 January 2021

Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats

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7 January 2021

Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe

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7 January 2021

CHILD CARE IN GENERAL PRACTICE: MENTALLY SUBNORMAL CHILDREN.

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7 January 2021

A pure parkinsonian syndrome following acute carbon monoxide intoxication

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7 January 2021

Progression after chronic manganese exposure

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7 January 2021

Glutathione peroxidase activity in Parkinson's disease brain

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7 January 2021

Mitochondrial membrane permeabilization in cell death

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7 January 2021

Mitochondrial respiratory chain disorders I: mitochondrial DNA defects

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7 January 2021

Mitochondrial respiratory chain disorders II: neurodegenerative disorders and nuclear gene defects

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7 January 2021

Mitochondrial disease

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7 January 2021

Mitochondrial function and parental sex effect in Huntington's disease

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7 January 2021

Biochemical abnormalities and excitotoxicity in Huntington's disease brain.

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7 January 2021

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

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7 January 2021

Mitochondrial involvement in Parkinson's disease

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402160

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17464321%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference