Nanotechnology approaches to eradicating HIV reservoirs (Q59359574)

PubMed publication ID

29879528

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29879528%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

title

Nanotechnology approaches to eradicating HIV reservoirs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6279622&resulttype=core&format=json

13 May 2020

1 reference

Shijie Cao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6279622&resulttype=core&format=json

13 May 2020

Kim A Woodrow

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6279622&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

4 June 2018

1 reference

PubMed publication ID

29879528

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29879528%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Pharmaceutics and Biopharmaceutics

30 March 2020

published in

1 reference

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13 May 2020

volume

138

1 reference

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13 May 2020

page(s)

48-63

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Follicular dendritic cells are a major reservoir for human immunodeficiency virus type 1 in lymphoid tissues facilitating infection of CD4+ T-helper cells

13 May 2020

cites work

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Rapid and sensitive detection of cell-associated HIV-1 in latently infected cell lines and in patient cells using sodium-n-butyrate induction and RT-PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Lysis of HIV-1-infected cells and inhibition of viral replication by universal receptor T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Human intestinal M cells display the sialyl Lewis A antigen.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

P-glycoprotein, secretory transport, and other barriers to the oral delivery of anti-HIV drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Mononuclear phagocyte differentiation, activation, and viral infection regulate matrix metalloproteinase expression: implications for human immunodeficiency virus type 1-associated dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A preponderance of CCR5(+) CXCR4(+) mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Prostratin: activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Neurologic and psychiatric complications of antiretroviral agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV-1 gp120 proteins and gp160 peptides are toxic to brain endothelial cells and neurons: possible pathway for HIV entry into the brain and HIV-associated dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Mechanism(s) promoting HIV-1 infection of primary unstimulated T lymphocytes in autologous B cell/T cell co-cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Lipid–Drug Association Enhanced HIV-1 Protease Inhibitor Indinavir Localization in Lymphoid Tissues and Viral Load Reduction: A Proof of Concept Study in HIV-2287-Infected Macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Combination antiretroviral therapy and the risk of myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Peripheral blood Dendritic cells are not a major reservoir for HIV type 1 in infected individuals on virally suppressive HAART.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Prostratin antagonizes HIV latency by activating NF-kappaB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Polyamides reveal a role for repression in latency within resting T cells of HIV-infected donors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Role of microglia in central nervous system infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

DC-SIGN-mediated infectious synapse formation enhances X4 HIV-1 transmission from dendritic cells to T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Selective targeting of antibody-conjugated nanoparticles to leukemic cells and primary T-lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Human immunodeficiency virus type 1 can establish latent infection in resting CD4+ T cells in the absence of activating stimuli

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Inhibitors of DNA methylation: beyond myelodysplastic syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV pharmacology: barriers to the eradication of HIV from the CNS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Dendritic-cell interactions with HIV: infection and viral dissemination

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

RNAi in combination with a ribozyme and TAR decoy for treatment of HIV infection in hematopoietic cell gene therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Suv39H1 and HP1gamma are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Transport of stavudine, delavirdine, and saquinavir across the blood-brain barrier by polybutylcyanoacrylate, methylmethacrylate-sulfopropylmethacrylate, and solid lipid nanoparticles

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV-1 proviral DNA excision using an evolved recombinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Improved oral bioavailability and brain transport of Saquinavir upon administration in novel nanoemulsion formulations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Mixed polymeric micelles for combination cancer chemotherapy through the concurrent delivery of multiple chemotherapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Electromagnetic interference in the permeability of saquinavir across the blood-brain barrier using nanoparticulate carriers

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Human macrophages support persistent transcription from unintegrated HIV-1 DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Greater viral rebound and reduced time to resume antiretroviral therapy after therapeutic immunization with the ALVAC-HIV vaccine (vCP1452)

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Characterization of carbosilane dendrimers as effective carriers of siRNA to HIV-infected lymphocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Nanoparticle therapeutics: an emerging treatment modality for cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Cell biology of HIV-1 infection of macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Lymphatic targeting of zidovudine using surface-engineered liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

The co-delivery of paclitaxel and Herceptin using cationic micellar nanoparticles

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Enhancing SIV-specific immunity in vivo by PD-1 blockade

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Kidney and central nervous system as reservoirs of HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

High frequencies of resting CD4+ T cells containing integrated viral DNA are found in rhesus macaques during acute lentivirus infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A randomized therapeutic vaccine trial of canarypox-HIV-pulsed dendritic cells vs. canarypox-HIV alone in HIV-1-infected patients on antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Epigenetic regulation of HIV-1 latency by cytosine methylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Alpha4(+)beta7(hi)CD4(+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

NanoART, neuroAIDS and CNS drug delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Long-term combination antiretroviral therapy is associated with the risk of coronary plaques in African Americans with HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Nanotechnology-based systems for the treatment and prevention of HIV/AIDS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Pure drug and polymer based nanotechnologies for the improved solubility, stability, bioavailability and targeting of anti-HIV drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

NanoART synthesis, characterization, uptake, release and toxicology for human monocyte-macrophage drug delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV Infection and Gut Mucosal Immune Function: Updates on Pathogenesis with Implications for Management and Intervention.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Half-antibody functionalized lipid-polymer hybrid nanoparticles for targeted drug delivery to carcinoembryonic antigen presenting pancreatic cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Magnetic nanoformulation of azidothymidine 5'-triphosphate for targeted delivery across the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Bryostatin modulates latent HIV-1 infection via PKC and AMPK signaling but inhibits acute infection in a receptor independent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Bryostatin-1 synergizes with histone deacetylase inhibitors to reactivate HIV-1 from latency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

AIDS clinical trials group 5197: a placebo-controlled trial of immunization of HIV-1-infected persons with a replication-deficient adenovirus type 5 vaccine expressing the HIV-1 core protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Carbosilane dendrimers to transfect human astrocytes with small interfering RNA targeting human immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

The large intestine as a major reservoir for simian immunodeficiency virus in macaques with long-term, nonprogressing infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Carbosilane dendrimers NN8 and NN16 form a stable complex with siGAG1

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Chemokine receptor 5 knockout strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Regulation of chromatin by histone modifications

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A randomized controlled trial of HIV therapeutic vaccination using ALVAC with or without Remune

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Activation of latent HIV using drug-loaded nanoparticles

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Influence of antiretroviral therapy on liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Brain delivery of transferrin coupled indinavir submicron lipid emulsions--pharmacokinetics and tissue distribution

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Gut-associated lymphoid tissues for the development of oral vaccines

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A human memory T cell subset with stem cell-like properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Surface modified nevirapine nanosuspensions for viral reservoir targeting: In vitro and in vivo evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

The Suv39H1 methyltransferase inhibitor chaetocin causes induction of integrated HIV-1 without producing a T cell response

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV reservoirs in vivo and new strategies for possible eradication of HIV from the reservoir sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: results from a multicentre randomized clinical study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Design and characterization of novel peptide-coated lipid nanoparticles for targeting anti-HIV drug to CD4 expressing cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Protein Kinase C: One Pathway towards the Eradication of Latent HIV-1 Reservoirs

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

T cell-specific siRNA delivery using antibody-conjugated chitosan nanoparticles

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Mechanistic determinants of biotherapeutics absorption following SC administration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Enhanced anti-HIV efficacy of indinavir after inclusion in CD4-targeted lipid nanoparticles

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

https://pubmed.ncbi.nlm.nih.gov/29879528

1 reference

12 December 2020

BET bromodomain inhibition as a novel strategy for reactivation of HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Pharmacodynamic and antiretroviral activities of combination nanoformulated antiretrovirals in HIV-1-infected human peripheral blood lymphocyte-reconstituted mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Validation of a generation 4 phosphorus-containing polycationic dendrimer for gene delivery against HIV-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Effect of early anti-retroviral therapy on the pathogenic changes in mucosal tissues of SIV infected rhesus macaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Intranasal administration of antiretroviral-loaded micelles for anatomical targeting to the brain in HIV.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Targeting HIV latency: pharmacologic strategies toward eradication

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Polymeric nanoparticles containing combination antiretroviral drugs for HIV type 1 treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Toxicology and clinical potential of nanoparticles

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Nano-NRTIs demonstrate low neurotoxicity and high antiviral activity against HIV infection in the brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Immune clearance of highly pathogenic SIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

The lungs as anatomical reservoirs of HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Absence of detectable HIV-1 viremia after treatment cessation in an infant

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Nanoparticle-based vaccine delivery for cancer immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A pilot study assessing the safety and latency-reversing activity of disulfiram in HIV-1-infected adults on antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV-1 persistence in CD4+ T cells with stem cell-like properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Ruxolitinib and tofacitinib are potent and selective inhibitors of HIV-1 replication and virus reactivation in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV-1 expression within resting CD4+ T cells after multiple doses of vorinostat

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Carbosilane dendrimers as gene delivery agents for the treatment of HIV infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Reactivation of HIV latency by a newly modified Ingenol derivative via protein kinase Cδ-NF-κB signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Anti-HIV drug particles may overcome lymphatic drug insufficiency and associated HIV persistence

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Glycosystems in nanotechnology: Gold glyconanoparticles as carrier for anti-HIV prodrugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Immunologic strategies for HIV-1 remission and eradication

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Non-viral vectors for gene-based therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Bioengineered vaults: self-assembling protein shell-lipophilic core nanoparticles for drug delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Long-acting three-drug combination anti-HIV nanoparticles enhance drug exposure in primate plasma and cells within lymph nodes and blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Selective HDAC inhibition for the disruption of latent HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

siRNA nanotherapeutics: a Trojan horse approach against HIV.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A nanoparticle-encapsulated non-nucleoside reverse-transcriptase inhibitor with enhanced anti-HIV-1 activity and prolonged circulation time in plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Chimeric antigen receptor T cells for sustained remissions in leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Anti-HIV drug-combination nanoparticles enhance plasma drug exposure duration as well as triple-drug combination levels in cells within lymph nodes and blood in primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Short chain fatty acids potently induce latent HIV-1 in T-cells by activating P-TEFb and multiple histone modifications

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

In vivo delivery of siRNA to the brain by carbosilane dendrimer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Viremic relapse after HIV-1 remission in a perinatally infected child

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Sustained-release nanoART formulation for the treatment of neuroAIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic options

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Inhibition of HIV-1 infection of primary CD4+ T-cells by gene editing of CCR5 using adenovirus-delivered CRISPR/Cas9.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV reservoirs as obstacles and opportunities for an HIV cure

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

RNA interference approaches for treatment of HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Pharmacodynamics of folic acid receptor targeted antiretroviral nanotherapy in HIV-1-infected humanized mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

The macrophage: a therapeutic target in HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Preferential loss of gut-homing α4β7 CD4+ T cells and their circulating functional subsets in acute HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Delivery and therapeutic applications of gene editing technologies ZFNs, TALENs, and CRISPR/Cas9.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

PLGA-PEG Nanoparticles Coated with Anti-CD45RO and Loaded with HDAC Plus Protease Inhibitors Activate Latent HIV and Inhibit Viral Spread

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Intensifying Antiretroviral Therapy With Raltegravir and Maraviroc During Early Human Immunodeficiency Virus (HIV) Infection Does Not Accelerate HIV Reservoir Reduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Nanotechnology Approaches for the Delivery of Exogenous siRNA for HIV Therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Nanoparticle-Based ARV Drug Combinations for Synergistic Inhibition of Cell-Free and Cell-Cell HIV Transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

The size of the expressed HIV reservoir predicts timing of viral rebound after treatment interruption

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Co-delivery of HIV-1 entry inhibitor and nonnucleoside reverse transcriptase inhibitor shuttled by nanoparticles: cocktail therapeutic strategy for antiviral therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

CCR5 Disruption in Induced Pluripotent Stem Cells Using CRISPR/Cas9 Provides Selective Resistance of Immune Cells to CCR5-tropic HIV-1 Virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Peripheral T Follicular Helper Cells Are the Major HIV Reservoir within Central Memory CD4 T Cells in Peripheral Blood from Chronically HIV-Infected Individuals on Combination Antiretroviral Therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Reversal of Latency as Part of a Cure for HIV-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Elevated Plasma Viral Loads in Romidepsin-Treated Simian Immunodeficiency Virus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Persistent HIV-1 replication maintains the tissue reservoir during therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Bryostatin-1 for latent virus reactivation in HIV-infected patients on antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Nanodrug formulations to enhance HIV drug exposure in lymphoid tissues and cells: clinical significance and potential impact on treatment and eradication of HIV/AIDS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Shocking HIV out of hiding: where are we with clinical trials of latency reversing agents?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

The clinical applications of genome editing in HIV.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Persistent HIV-1 replication during antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Treatment of the Immune-Related Adverse Effects of Immune Checkpoint Inhibitors: A Review.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Latency reversal and viral clearance to cure HIV-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

A RNA nanotechnology platform for a simultaneous two-in-one siRNA delivery and its application in synergistic RNAi therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Ongoing Clinical Trials of Human Immunodeficiency Virus Latency-Reversing and Immunomodulatory Agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Triple Drug Combination of Zidovudine, Efavirenz and Lamivudine Loaded Lactoferrin Nanoparticles: an Effective Nano First-Line Regimen for HIV Therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Experimental Approaches for Eliminating Latent HIV.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

In Vivo Delivery of CRISPR/Cas9 for Therapeutic Gene Editing: Progress and Challenges

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Development of antibody-modified chitosan nanoparticles for the targeted delivery of siRNA across the blood-brain barrier as a strategy for inhibiting HIV replication in astrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Delivery technologies for genome editing

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In Vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Dual Targeting Nanoparticle Stimulates the Immune System To Inhibit Tumor Growth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Anti-proliferative therapy for HIV cure: a compound interest approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Early initiation of antiretroviral treatment postSIV infection does not resolve lymphoid tissue activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Interval dosing with the HDAC inhibitor vorinostat effectively reverses HIV latency

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Novel nanoformulation to mitigate co-effects of drugs of abuse and HIV-1 infection: towards the treatment of NeuroAIDS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Potent and broad HIV-neutralizing antibodies in memory B cells and plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Reactivation of HIV-1 from Latency by an Ingenol Derivative from Euphorbia Kansui.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Genome editing of the HIV co-receptors CCR5 and CXCR4 by CRISPR-Cas9 protects CD4+ T cells from HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Pharmacokinetic and Tissue Distribution Profile of Long Acting Tenofovir Alafenamide and Elvitegravir Loaded Nanoparticles in Humanized Mice Model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Defining total-body AIDS-virus burden with implications for curative strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

In Vivo Suppression of HIV Rebound by Didehydro-Cortistatin A, a "Block-and-Lock" Strategy for HIV-1 Treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Chidamide, a histone deacetylase inhibitor-based anticancer drug, effectively reactivates latent HIV-1 provirus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Optimization and comparison of CD4-targeting lipid-polymer hybrid nanoparticles using different binding ligands.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Engineering chimeric antigen receptor-T cells for cancer treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA induces homology-directed DNA repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/29879528

12 December 2020

10.1016/J.EJPB.2018.06.002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6279622&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6279622&resulttype=core&format=json

13 May 2020

PubMed publication ID

29879528

1 reference