Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2 (Q39315996)

10 September 2017

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2 (English)

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10 September 2017

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3

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10 September 2017

8

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10 September 2017

Isabel Novoa

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Heather P Harding

object named as

Heather P Harding

series ordinal

9

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Randal J Kaufman

series ordinal

7

object named as

Randal J Kaufman

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10 September 2017

2

Céline Jousse

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10 September 2017

6

Donalyn Scheuner

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10 September 2017

Phoebe D Lu

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10 September 2017

Yuhong Zhang

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4

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10 September 2017

language of work or name

English

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publication date

8 January 2004

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10 September 2017

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10 September 2017

23

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1

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10 September 2017

169-179

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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

10 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Orchestrating the unfolded protein response in health and disease

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Transcriptional and translational control in the Mammalian unfolded protein response

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Gene-specific regulation by general translation factors

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Molecular pathways of protein synthesis inhibition during brain reperfusion: implications for neuronal survival or death

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Regulation of antioxidant metabolism by translation initiation factor 2alpha

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Regulated translation initiation controls stress-induced gene expression in mammalian cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Perk is essential for translational regulation and cell survival during the unfolded protein response

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Expression monitoring by hybridization to high-density oligonucleotide arrays

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

The regulation of reactive oxygen species production during programmed cell death

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Controlling Signal Transduction with Synthetic Ligands

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Stress-induced gene expression requires programmed recovery from translational repression

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Packaging system for rapid production of murine leukemia virus vectors with variable tropism

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

The role of monoamine metabolism in oxidative glutamate toxicity.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Protein kinase C activation inhibits glutamate-induced cytotoxicity in a neuronal cell line

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Regulation of translational initiation during cellular responses to stress

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Local cerebral blood flow during hibernation, a model of natural tolerance to "cerebral ischemia".

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Induction and expression of long- and short-term neurosecretory potentiation in a neural cell line

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Oxidative glutamate toxicity can be a component of the excitotoxicity cascade.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Hibernation in ground squirrels induces state and species-specific tolerance to hypoxia and aglycemia: an in vitro study in hippocampal slices

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271668

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

21 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/14713949

12 December 2020

Determination of glutathione and glutathione disulfide in biological samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/14713949

12 December 2020

Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/14713949

12 December 2020

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/14713949

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600030

1 reference

10 September 2017

1 reference

10 September 2017

PubMed publication ID

14713949

1 reference