The roles of kinases in familial Parkinson's disease. (Q36989256)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

review article

1 reference

title

The roles of kinases in familial Parkinson's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Ming Guo

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Jie Shen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Mark R Cookson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Ted Dawson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Edward A Fon

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

0 references

publication date

1 October 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

issue

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

11865-11868

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

Association between early-onset Parkinson's disease and mutations in the parkin gene

9 January 2020

cites work

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Loss of locus coeruleus neurons and reduced startle in parkin null mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Parkin-deficient mice are not a robust model of parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Molecular determinants for the complex binding specificity of the PDZ domain in PICK1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Proteomic analysis of parkin knockout mice: alterations in energy metabolism, protein handling and synaptic function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Kinase activity of mutant LRRK2 mediates neuronal toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

The familial Parkinsonism gene LRRK2 regulates neurite process morphology

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Proteasome-independent functions of ubiquitin in endocytosis and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Leucine-rich repeat kinase 2 associates with lipid rafts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

LRRK2 low-penetrance mutations (Gly2019Ser) and risk alleles (Gly2385Arg)-linking familial and sporadic Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

The R1441C mutation of LRRK2 disrupts GTP hydrolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Mechanistic insight into the dominant mode of the Parkinson's disease-associated G2019S LRRK2 mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Leucine-rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson's disease R1441C/G mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17978026

12 December 2020

10.1523/JNEUROSCI.3695-07.2007

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17978026%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

17978026

1 reference