The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection (Q36737159)

16 August 2017

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title

The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection (English)

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16 August 2017

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3

Rafi Ahmed

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16 August 2017

4

Gordon J Freeman

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16 August 2017

1

Arlene H Sharpe

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16 August 2017

2

E John Wherry

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16 August 2017

language of work or name

English

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publication date

1 March 2007

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16 August 2017

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16 August 2017

volume

8

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16 August 2017

issue

3

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16 August 2017

page(s)

239-245

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16 August 2017

cites work

The B7 family revisited

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

The PD-1-PD-L pathway in immunological tolerance

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNF

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Endothelial expression of PD‐L1 and PD‐L2 down‐regulates CD8+ T cell activation and cytolysis

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

B7-H1 (programmed death-1 ligand) on dendritic cells is involved in the induction and maintenance of T cell anergy.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Blockade of the interaction between PD-1 and PD-L1 accelerates graft arterial disease in cardiac allografts

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Tissue expression of PD-L1 mediates peripheral T cell tolerance.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Induction of a gene expression program in dendritic cells with a cross-linking IgM antibody to the co-stimulatory molecule B7-DC.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Immunomodulation using the recombinant monoclonal human B7-DC cross-linking antibody rHIgM12.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Regulation of PD‐1, PD‐L1, and PD‐L2 expression during normal and autoimmune responses

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Facilitation of beta selection and modification of positive selection in the thymus of PD-1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Programmed death-1 (PD-1):PD-ligand 1 interactions inhibit TCR-mediated positive selection of thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Absence of Programmed Death Receptor 1 Alters Thymic Development and Enhances Generation of CD4/CD8 Double-Negative TCR-Transgenic T Cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Trophoblast CD274 (B7-H1) is differentially expressed across gestation: influence of oxygen concentration

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

A critical role for the programmed death ligand 1 in fetomaternal tolerance

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

CD4+PD-1+ T cells acting as regulatory cells during the induction of anterior chamber-associated immune deviation.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Differential effects of costimulatory pathway modulation on corneal allograft survival

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Prevention of experimental autoimmune encephalomyelitis by transfer of embryonic stem cell-derived dendritic cells expressing myelin oligodendrocyte glycoprotein peptide along with TRAIL or programmed death-1 ligand.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Differential role of programmed death-ligand 1 [corrected] and programmed death-ligand 2 [corrected] in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Regulation of T cell activation and tolerance by PDL2

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Oscillating CD8(+) T cell effector functions after antigen recognition in the liver.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

PD-1 inhibits antiviral immunity at the effector phase in the liver

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Effector and memory T-cell differentiation: implications for vaccine development

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Memory CD8 T-cell differentiation during viral infection

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

T cells and viral persistence: lessons from diverse infections

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Expression of the interleukin-7 receptor alpha chain (CD127) on virus-specific CD8+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Human rhinoviruses inhibit the accessory function of dendritic cells by inducing sialoadhesin and B7-H1 expression

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

B7-H1 (CD274) inhibits the development of herpetic stromal keratitis (HSK).

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Expression of programmed death-1 ligand (PD-L) 1, PD-L2, B7-H3, and inducible costimulator ligand on human respiratory tract epithelial cells and regulation by respiratory syncytial virus and type 1 and 2 cytokines

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Respiratory syncytial virus infection suppresses lung CD8+ T-cell effector activity and peripheral CD8+ T-cell memory in the respiratory tract

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Induction of CTLA-4-mediated anergy contributes to persistent colonization in the murine model of gastric Helicobacter pylori infection

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Increased frequency of activated T-cells in the Helicobacter pylori-infected antrum and duodenum.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Expression of B7-H1 on gastric epithelial cells: its potential role in regulating T cells during Helicobacter pylori infection

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Induction of tolerance by Porphyromonas gingivalis on APCS: a mechanism implicated in periodontal infection

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Tuberculosis: back on the immunologists' agenda

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Chlamydia trachomatis infection alters the development of memory CD8+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Role of the programmed Death-1 pathway in the suppressive activity of alternatively activated macrophages in experimental cysticercosis.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

PD-L1 and PD-L2 have distinct roles in regulating host immunity to cutaneous leishmaniasis

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

A PD-1 polymorphism is associated with disease progression in multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

A putative regulatory polymorphism in PD-1 is associated with nephropathy in a population-based cohort of systemic lupus erythematosus patients

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Association of a putative regulatory polymorphism in the PD-1 gene with susceptibility to type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

A new haplotype of PDCD1 is associated with rheumatoid arthritis in Hong Kong Chinese.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Association of a programmed death 1 gene polymorphism with the development of rheumatoid arthritis, but not systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Association of a PDCD1 polymorphism with renal manifestations in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Association of the PD-1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Programmed death-1 gene polymorphisms in patients with systemic lupus erythematosus in Taiwan.

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Association of the programmed cell death 1 (PDCD1) gene polymorphism with ankylosing spondylitis in the Korean population

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Association of PDCD1 with susceptibility to systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

PDCD1: a tissue-specific susceptibility locus for inherited inflammatory disorders

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Lyme disease: a review of aspects of its immunology and immunopathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Autoimmunity in coxsackievirus B3 induced myocarditis

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Epstein-Barr virus etiology in rheumatoid synovitis

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Autoimmunity and malaria: what are they doing together?

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Parasitic worms and inflammatory diseases

1 reference

https://api.crossref.org/works/10.1038%2FNI1443

7 January 2021

Identifiers

DOI

10.1038/NI1443

1 reference

16 August 2017

1 reference