Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice. (Q36609044)

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6 January 2020

title

Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice (English)

1 reference

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6 January 2020

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Arunika Mukhopadhaya

1

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6 January 2020

Tadashi Hanafusa

2

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6 January 2020

Irene Jarchum

3

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6 January 2020

Yi-Guang Chen

4

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6 January 2020

Yoshiko Iwai

5

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6 January 2020

David V Serreze

6

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6 January 2020

Teresa P DiLorenzo

9

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6 January 2020

language of work or name

English

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publication date

22 April 2008

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Proceedings of the National Academy of Sciences of the United States of America

6 January 2020

published in

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6 January 2020

volume

105

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6 January 2020

issue

17

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6 January 2020

page(s)

6374-6379

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Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes

6 January 2020

cites work

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The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection

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Differential antigen processing by dendritic cell subsets in vivo

30 September 2017

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The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice

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Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4.

30 September 2017

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Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase

30 September 2017

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Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4.

30 September 2017

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Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo

30 September 2017

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In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination

30 September 2017

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Tolerogenic dendritic cells

30 September 2017

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During the early prediabetic period in NOD mice, the pathogenic CD8(+) T-cell population comprises multiple antigenic specificities

30 September 2017

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Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

30 September 2017

1 reference

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Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes.

30 September 2017

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In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

30 September 2017

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Memory CD8(+) T cells undergo peripheral tolerance

30 September 2017

1 reference

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

30 September 2017

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The NOD mouse model of type 1 diabetes: as good as it gets?

30 September 2017

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The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

30 September 2017

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Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool

30 September 2017

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Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice.

28 June 2018

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On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes

20 September 2018

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Histological analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells

20 September 2018

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Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim.

20 September 2018

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Enhanced pathogenicity of diabetogenic T cells escaping a non-MHC gene-controlled near death experience.

20 September 2018

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Qualitative and quantitative abnormalities in splenic dendritic cell populations in NOD mice.

20 September 2018

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Cell-intrinsic effects of non-MHC NOD genes on dendritic cell generation in vivo.

20 September 2018

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NOD mice have a generalized defect in their response to transplantation tolerance induction.

20 September 2018

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Genetic control of diabetogenesis in NOD/Lt mice. Development and analysis of congenic stocks.

20 September 2018

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Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions

20 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18430797

12 December 2020

Defective CD8+ T Cell Peripheral Tolerance in Nonobese Diabetic Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18430797

12 December 2020

Intrinsic in vitro abnormalities in dendritic cell generation caused by non-MHC non-obese diabetic genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18430797

12 December 2020

Langerhans Cells Activate Naive Self-Antigen-Specific CD8 T Cells in the Steady State

1 reference

https://pubmed.ncbi.nlm.nih.gov/18430797

12 December 2020

Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. II. Expression in situ in lymphoid and nonlymphoid tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/18430797

12 December 2020

Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18430797

12 December 2020

Phenotypic and Functional Characteristics of BM-Derived DC from NOD and Non-Diabetes-Prone Strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/18430797

12 December 2020

Identifiers

DOI

10.1073/PNAS.0802644105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18430797%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18430797%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

18430797

1 reference