Tunable and reversible drug control of protein production via a self-excising degron. (Q35977821)

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20 February 2020

title

Tunable and reversible drug control of protein production via a self-excising degron (English)

1 reference

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20 February 2020

1

1 reference

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20 February 2020

6

Richard K Plemper

1 reference

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20 February 2020

5

Stefanie A Krumm

1 reference

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20 February 2020

author name string

Conor L Jacobs

2

1 reference

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20 February 2020

Yunwen Huo

3

1 reference

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20 February 2020

Jin Yang

4

1 reference

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20 February 2020

Roger Y Tsien

7

1 reference

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20 February 2020

Michael Z Lin

8

1 reference

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20 February 2020

publication date

27 July 2015

1 reference

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20 February 2020

published in

Nature Chemical Biology

1 reference

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20 February 2020

volume

11

1 reference

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20 February 2020

issue

9

1 reference

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20 February 2020

page(s)

713-720

1 reference

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describes a project that uses

20 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4543534/fullTextXML

based on heuristic

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Fluorescent and photo-oxidizing TimeSTAMP tags track protein fates in light and electron microscopy

2 October 2017

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Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

2 October 2017

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Plasticity in structural and functional interactions between the phosphoprotein and nucleoprotein of measles virus.

2 October 2017

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Identification of hydrophobic tags for the degradation of stabilized proteins

2 October 2017

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Small-molecule displacement of a cryptic degron causes conditional protein degradation

2 October 2017

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Functional genetics in Apicomplexa: potentials and limits.

2 October 2017

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Vigilance and validation: Keys to success in RNAi screening

2 October 2017

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Poxvirus interleukin-4 expression overcomes inherent resistance and vaccine-induced immunity: pathogenesis, prophylaxis, and antiviral therapy

2 October 2017

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A general chemical method to regulate protein stability in the mammalian central nervous system

2 October 2017

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Enhanced antitumor effects of an engineered measles virus Edmonston strain expressing the wild-type N, P, L genes on human renal cell carcinoma

2 October 2017

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Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models

2 October 2017

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An auxin-based degron system for the rapid depletion of proteins in nonplant cells.

2 October 2017

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2 October 2017

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The role of the putative 3' end processing endonuclease Ysh1p in mRNA and snoRNA synthesis

2 October 2017

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Structural determinants for membrane association and dynamic organization of the hepatitis C virus NS3-4A complex

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Quantification of protein half-lives in the budding yeast proteome

2 October 2017

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2 October 2017

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Measles virus phosphoprotein gene products: conformational flexibility of the P/V protein amino-terminal domain and C protein infectivity factor function

2 October 2017

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Short tetracysteine tags to beta-tubulin demonstrate the significance of small labels for live cell imaging

2 October 2017

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Exploration of essential gene functions via titratable promoter alleles

2 October 2017

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Measles virus protein interactions in yeast: new findings and caveats.

2 October 2017

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An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

2 October 2017

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Global analysis of protein localization in budding yeast

2 October 2017

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A protein knockdown strategy to study the function of beta-catenin in tumorigenesis

2 October 2017

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Establishment of conditional vectors for hairpin siRNA knockdowns

2 October 2017

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Strength of envelope protein interaction modulates cytopathicity of measles virus

2 October 2017

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Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

2 October 2017

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Measles viruses on throat swabs from measles patients use signaling lymphocytic activation molecule (CDw150) but not CD46 as a cellular receptor

2 October 2017

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Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

2 October 2017

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Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoter

2 October 2017

1 reference

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Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds

2 October 2017

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Elevated recombination rates in transcriptionally active DNA

2 October 2017

1 reference

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Simeprevir: a macrocyclic HCV protease inhibitor

2 October 2017

1 reference

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Broadly applicable methodology for the rapid and dosable small molecule-mediated regulation of transcription factors in human cells.

11 July 2018

1 reference

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A rugged and accurate liquid chromatography-tandem mass spectrometry method for the determination of asunaprevir, an NS3 protease inhibitor, in plasma

11 July 2018

1 reference

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A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules

11 July 2018

1 reference

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Kinetic study of de novo chromophore maturation of fluorescent proteins.

11 July 2018

1 reference

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Determining protein half-lives

24 September 2018

1 reference

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Conditional protein alleles using knockin mice and a chemical inducer of dimerization

24 September 2018

1 reference

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Targeting protein stability with a small molecule

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26214256

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.1869

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214256%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214256%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

26214256

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214256%20AND%20SRC:MED&resulttype=core&format=json