Conditional protein alleles using knockin mice and a chemical inducer of dimerization (Q44702968)

5 December 2017

title

Conditional protein alleles using knockin mice and a chemical inducer of dimerization (English)

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5 December 2017

Kryn Stankunas

1

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5 December 2017

J Henri Bayle

2

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5 December 2017

Jason E Gestwicki

3

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5 December 2017

Yun-Ming Lin

4

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5 December 2017

Thomas J Wandless

5

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5 December 2017

Gerald R Crabtree

6

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5 December 2017

publication date

1 December 2003

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5 December 2017

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5 December 2017

volume

12

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5 December 2017

issue

6

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5 December 2017

page(s)

1615-1624

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Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

5 December 2017

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Controlling protein association and subcellular localization with a synthetic ligand that induces heterodimerization of proteins

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Controlling programmed cell death with a cyclophilin-cyclosporin-based chemical inducer of dimerization

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A chemical switch for inhibitor-sensitive alleles of any protein kinase

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7 January 2021

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

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Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation

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Sonographic staging of the developmental status of mouse embryos in utero

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7 January 2021

Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue

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7 January 2021

Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP

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7 January 2021

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

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GSK-3: tricks of the trade for a multi-tasking kinase

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Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature

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7 January 2021

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

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Genetic control of the cell-division cycle in yeast. I. Detection of mutants

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7 January 2021

FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse

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7 January 2021

Dimeric ligands define a role for transcriptional activation domains in reinitiation

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7 January 2021

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

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Signal transduction in T lymphocytes using a conditional allele of Sos

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Tor signalling in bugs, brain and brawn

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7 January 2021

Methotrexate inhibits proteolysis of dihydrofolate reductase by the N-end rule pathway.

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7 January 2021

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

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7 January 2021

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

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7 January 2021

Analysis of a conditional degradation signal in yeast and mammalian cells

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7 January 2021

Inducible gene expression and protein translocation using nontoxic ligands identified by a mammalian three-hybrid screen

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7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

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7 January 2021

Gene silencing in mammals by small interfering RNAs

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7 January 2021

Cre recombinase: The universal reagent for genome tailoring

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7 January 2021

Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe

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7 January 2021

Posttranslational regulation of proteins by fusions to steroid-binding domains

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7 January 2021

Mechanistic studies of a signaling pathway activated by the organic dimerizer FK1012

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7 January 2021

A humanized system for pharmacologic control of gene expression

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7 January 2021

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

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7 January 2021

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

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7 January 2021

Controlling Signal Transduction with Synthetic Ligands

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7 January 2021

A general strategy for producing conditional alleles of Src-like tyrosine kinases

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7 January 2021

Functional analysis of Fas signaling in vivo using synthetic inducers of dimerization

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7 January 2021

Structure of GSK3beta reveals a primed phosphorylation mechanism

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7 January 2021

Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

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7 January 2021

Inducible protein knockout reveals temporal requirement of CaMKII reactivation for memory consolidation in the brain

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7 January 2021

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7 January 2021

Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins

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7 January 2021

10.1016/S1097-2765(03)00491-X

Identifiers

DOI

1 reference

5 December 2017

1 reference