Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease (Q35915771)

11 August 2017

1 reference

title

Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease (English)

1 reference

11 August 2017

4

P Michael Conn

1 reference

11 August 2017

author name string

Alfredo Ulloa-Aguirre

series ordinal

1

1 reference

11 August 2017

Jo Ann Janovick

series ordinal

2

1 reference

11 August 2017

Shaun P Brothers

series ordinal

3

1 reference

11 August 2017

language of work or name

1 reference

1 November 2004

1 reference

11 August 2017

1 reference

11 August 2017

volume

5

1 reference

11 August 2017

issue

11

1 reference

11 August 2017

page(s)

821-837

1 reference

Integration of endoplasmic reticulum signaling in health and disease

11 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Biological activity and pathological implications of misfolded proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

From computer simulations to human disease: emerging themes in protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Misfolding of membrane proteins in health and disease: the lady or the tiger?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

The linkage between protein folding and functional cooperativity: two sides of the same coin?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Quality Control and Protein Folding in the Secretory Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Setting the standards: quality control in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Quality control in the secretory assembly line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

ER quality control: towards an understanding at the molecular level

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Quality control in the endoplasmic reticulum protein factory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Protein misfolding, evolution and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Protein misfolding in Alzheimer's and Parkinson's disease: genetics and molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

'Unfolding' pathways in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

21 January 2018

Conformational disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Neurodegenerative disorders of protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Protein misfolding and disease; protein refolding and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Chemical chaperones: a pharmacological strategy for disorders of protein folding and trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Therapeutic approaches to protein-misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Receptor-misrouting: an unexpectedly prevalent and rescuable etiology in gonadotropin-releasing hormone receptor-mediated hypogonadotropic hypogonadism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Protein origami: therapeutic rescue of misfolded gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Misrouted cell surface GnRH receptors as a disease aetiology for congenital isolated hypogonadotrophic hypogonadism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

The tail of the gonadotrophin-releasing hormone receptor: desensitization at, and distal to, G protein-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Gonadotropin-releasing hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Out of the ER--outfitters, escorts and guides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Pharmacological chaperones: a new twist on receptor folding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Chaperone-assisted protein folding in the cell cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Molecular chaperones in the cytosol: from nascent chain to folded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

G protein-coupled receptor interacting proteins: emerging roles in localization and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Odorant receptor localization to olfactory cilia is mediated by ODR-4, a novel membrane-associated protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Drosophila ninaA gene encodes an eye-specific cyclophilin (cyclosporine A binding protein)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

The ninaA gene required for visual transduction in Drosophila encodes a homologue of cyclosporin A-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

The cyclophilin homolog ninaA is required in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Crystal structure of the zeta isoform of the 14-3-3 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

The contribution of N-glycans and their processing in the endoplasmic reticulum to glycoprotein biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Association of calnexin with wild type and mutant AVPR2 that causes nephrogenic diabetes insipidus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Lectin control of protein folding and sorting in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

The molecular chaperone calnexin binds Glc1Man9GlcNAc2 oligosaccharide as an initial step in recognizing unfolded glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Oligosaccharide binding characteristics of the molecular chaperones calnexin and calreticulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Chaperone selection during glycoprotein translocation into the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Protein glucosylation and its role in protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Shattuck lecture--neurodegenerative diseases and prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Altered aggregation properties of mutant gamma-crystallins cause inherited cataract

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

In vitro unfolding, refolding, and polymerization of human gammaD crystallin, a protein involved in cataract formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Impairment of the ubiquitin-proteasome system by protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Orchestrating the unfolded protein response in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Transcriptional and translational control in the Mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

The LDL receptor locus in familial hypercholesterolemia: mutational analysis of a membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Defective intracellular transport is the molecular basis of rhodopsin-dependent dominant retinal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Transgenic mice carrying the dominant rhodopsin mutation P347S: evidence for defective vectorial transport of rhodopsin to the outer segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Vasopressin receptor mutations and nephrogenic diabetes insipidus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Molecular and cellular defects in nephrogenic diabetes insipidus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Nephrogenic diabetes insipidus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Correcting temperature-sensitive protein folding defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Temperature-sensitive ZAP70 mutants degrading through a proteasome-independent pathway. Restoration of a kinase domain mutant by Cdc37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Functional rescue of the nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutants G185C and R202C by a second site suppressor mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Molecular basis of hypogonadotropic hypogonadism: restoration of mutant (E(90)K) GnRH receptor function by a deletion at a distant site

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Ligands act as pharmacological chaperones and increase the efficiency of delta opioid receptor maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Appropriate polarization following pharmacological rescue of V2 vasopressin receptors encoded by X-linked nephrogenic diabetes insipidus alleles involves a conformation of the receptor that also attains mature glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Misfolding of mutant aquaporin-2 water channels in nephrogenic diabetes insipidus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Natural osmolyte trimethylamine N-oxide corrects assembly defects of mutant branched-chain alpha-ketoacid decarboxylase in maple syrup urine disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

A conditional mutation affecting localization of the Menkes disease copper ATPase. Suppression by copper supplementation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Chemical chaperones reduce aggregate formation and cell death caused by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Trimethylamine N-oxide-induced cooperative folding of an intrinsically unfolded transcription-activating fragment of human glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Manipulating the amyloid-beta aggregation pathway with chemical chaperones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Prevention of transthyretin amyloid disease by changing protein misfolding energetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

In vivo reversal of amyloid-beta lesions in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Therapeutic strategies for human amyloid diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Galactonojirimycin derivatives restore mutant human beta-galactosidase activities expressed in fibroblasts from enzyme-deficient knockout mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Retinoids assist the cellular folding of the autosomal dominant retinitis pigmentosa opsin mutant P23H.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Identification and pharmacological correction of a membrane trafficking defect associated with a mutation in the sulfonylurea receptor causing familial hyperinsulinism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

P-glycoprotein. Associations between domains and between domains and molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Determining the structure and mechanism of the human multidrug resistance P-glycoprotein using cysteine-scanning mutagenesis and thiol-modification techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Recovering antibody secretion using a hapten ligand as a chemical chaperone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Small molecule modulation of Smoothened activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human delta opioid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Newly synthesized human delta opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the cytosol, deglycosylated, ubiquitinated, and degraded by the proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Substituted indole-5-carboxamides and -acetamides as potent nonpeptide GnRH receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Potent nonpeptide GnRH receptor antagonists derived from substituted indole-5-carboxamides and -acetamides bearing a pyridine side-chain terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Unexpected effects of epitope and chimeric tags on gonadotropin-releasing hormone receptors: implications for understanding the molecular etiology of hypogonadotropic hypogonadism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Evolved regulation of gonadotropin-releasing hormone receptor cell surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

G-protein-coupled receptor dimerization: modulation of receptor function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Photobleaching fluorescence resonance energy transfer reveals ligand-induced oligomer formation of human somatostatin receptor subtypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Conversion of a gonadotropin-releasing hormone antagonist to an agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Gonadotropin releasing hormone agonist provokes homologous receptor microaggregation: an early event in seven-transmembrane receptor mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Gonadotropin-releasing hormone receptor microaggregation. Rate monitored by fluorescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Heterodimerization is required for the formation of a functional GABA(B) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Truncated V2 vasopressin receptors as negative regulators of wild-type V2 receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Selective modulation of wild type receptor functions by mutants of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5delta32.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Inhibition of Gonadotropin-Releasing Hormone Receptor Signaling by Expression of a Splice Variant of the Human Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Dominant-negative action of disease-causing gonadotropin-releasing hormone receptor (GnRHR) mutants: a trait that potentially coevolved with decreased plasma membrane expression of GnRHR in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Two defective heterozygous luteinizing hormone receptors can rescue hormone action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Cis- and trans-activation of hormone receptors: the LH receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

Human loss-of-function gonadotropin-releasing hormone receptor mutants retain wild-type receptors in the endoplasmic reticulum: molecular basis of the dominant-negative effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2004.00232.X

10.1111/J.1600-0854.2004.00232.X

21 January 2018

Identifiers

DOI

1 reference

11 August 2017

1 reference