Aberrant ubiquitin-mediated proteolysis of cell cycle regulatory proteins and oncogenesis (Q35094511)

6 August 2017

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title

Aberrant ubiquitin-mediated proteolysis of cell cycle regulatory proteins and oncogenesis (English)

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6 August 2017

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Tarig Bashir

1

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6 August 2017

Michele Pagano

series ordinal

2

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6 August 2017

language of work or name

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1 January 2003

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Advances in Cancer Research

6 August 2017

published in

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6 August 2017

volume

88

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6 August 2017

page(s)

101-144

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Expression of cyclin A and D proteins in prostate cancer and their relation to clinopathological variables and patient survival

6 August 2017

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Cyclin encoded by KS herpesvirus

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The E2F transcription factor is a cellular target for the RB protein

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7 January 2021

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

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S-phase kinase-associated protein 2 expression in non-Hodgkin's lymphoma inversely correlates with p27 expression and defines cells in S phase

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Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation

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Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

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The myc oncogene: its role in transformation and differentiation

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G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts

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Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment.

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Distinct roles for cyclins E and A during DNA replication complex assembly and activation

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7 January 2021

Fos and Jun: the AP-1 connection

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7 January 2021

E1A signaling to p53 involves the p19(ARF) tumor suppressor

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7 January 2021

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

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7 January 2021

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

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7 January 2021

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

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Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

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7 January 2021

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

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7 January 2021

Cyclin E in human cancers.

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7 January 2021

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7 January 2021

Differential regulation of E2F transactivation by cyclin/cdk2 complexes

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7 January 2021

The regulation of E2F by pRB-family proteins

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7 January 2021

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

A question of balance: the role of cyclin-kinase inhibitors in development and tumorigenesis

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7 January 2021

Degradation of p27(Kip) cdk inhibitor triggered by Kaposi's sarcoma virus cyclin-cdk6 complex

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7 January 2021

Centrosome overduplication, increased ploidy and transformation in cells expressing endoplasmic reticulum-associated cyclin A2

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7 January 2021

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

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7 January 2021

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

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7 January 2021

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

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7 January 2021

Mutational analysis of the human cyclin-dependent kinase inhibitor p27kip1 in primary breast carcinomas

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7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

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7 January 2021

myc boxes, which are conserved in myc family proteins, are signals for protein degradation via the proteasome

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7 January 2021

The CDKN2A (p16) gene and human cancer.

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7 January 2021

A splice variant of Skp2 is retained in the cytoplasm and fails to direct cyclin D1 ubiquitination in the uterine cancer cell line SK-UT.

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7 January 2021

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

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7 January 2021

Protein stabilization: a common consequence of mutations in independently derived v-Myc alleles.

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7 January 2021

Ubiquitination of free cyclin D1 is independent of phosphorylation on threonine 286

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7 January 2021

G1/S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb

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7 January 2021

The complexity of p53 modulation: emerging patterns from divergent signals

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7 January 2021

Cyclin is degraded by the ubiquitin pathway

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7 January 2021

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7 January 2021

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

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7 January 2021

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7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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7 January 2021

Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins

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7 January 2021

Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F.

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7 January 2021

Mdm2 promotes the rapid degradation of p53

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7 January 2021

Regulation of cell proliferation by the E2F transcription factors

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7 January 2021

A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

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7 January 2021

Roles of ubiquitin-mediated proteolysis in cell cycle control

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7 January 2021

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7 January 2021

Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas

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7 January 2021

Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas

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7 January 2021

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

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7 January 2021

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

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7 January 2021

Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein

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7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

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7 January 2021

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

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7 January 2021

The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo

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7 January 2021

p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer

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7 January 2021

Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export

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7 January 2021

The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

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7 January 2021

RING finger proteins: mediators of ubiquitin ligase activity

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7 January 2021

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression

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7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

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7 January 2021

Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 3' untranslated sequences

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7 January 2021

Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome

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7 January 2021

How proteolysis drives the cell cycle

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7 January 2021

The F-box protein family.

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7 January 2021

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

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7 January 2021

p53: puzzle and paradigm

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7 January 2021

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

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7 January 2021

Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.

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7 January 2021

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

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7 January 2021

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

1 reference

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7 January 2021

The jun and fos protein families are both required for cell cycle progression in fibroblasts

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7 January 2021

Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

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7 January 2021

Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members

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7 January 2021

Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity

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7 January 2021

New functional activities for the p21 family of CDK inhibitors

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7 January 2021

Characterization of the p53-dependent postmitotic checkpoint following spindle disruption

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7 January 2021

Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage

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7 January 2021

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

1 reference

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7 January 2021

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

1 reference

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7 January 2021

c-myc and c-myb protein degradation: effect of metabolic inhibitors and heat shock

1 reference

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7 January 2021

New light on Myc and Myb. Part II. Myb.

1 reference

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7 January 2021

New light on Myc and Myb. Part I. Myc.

1 reference

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7 January 2021

Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis

1 reference

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7 January 2021

Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas--relationship to amplification and mRNA levels of CDK4 and CCND1.

1 reference

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7 January 2021

Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Modulation of p27(Kip1) levels by the cyclin encoded by Kaposi's sarcoma-associated herpesvirus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

myc function and regulation

1 reference

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7 January 2021

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene

1 reference

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7 January 2021

D-type cyclin-dependent kinase activity in mammalian cells

1 reference

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7 January 2021

Differentiation of mouse erythroleukemia cells is blocked by late up-regulation of a c-myb transgene

1 reference

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7 January 2021

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

1 reference

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7 January 2021

Cell transformation by c-fos requires an extended period of expression and is independent of the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Control of pRB phosphorylation

1 reference

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

The MDM2 gene amplification database

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Principles of CDK regulation

1 reference

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7 January 2021

Cyclin D and oncogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

A novel cyclin encoded by a bcl1-linked candidate oncogene

1 reference

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7 January 2021

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

1 reference

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7 January 2021

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

The myb gene family in cell growth, differentiation and apoptosis

1 reference

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7 January 2021

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

1 reference

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7 January 2021

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

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7 January 2021

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Subunits and substrates of the anaphase-promoting complex

1 reference

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7 January 2021

The anaphase-promoting complex: proteolysis in mitosis and beyond

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Proteasome-dependent degradation of p27/kip1 in gliomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Different roles for cyclins D1 and E in regulation of the G1-to-S transition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Cyclin D1 and D3 associate with the SCF complex and are coordinately elevated in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Ras enhances Myc protein stability.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

AP-1 in cell proliferation and survival

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Cyclin E-CDK2 is a regulator of p27Kip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Regulation of G1 phase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

G1 phase progression: cycling on cue

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

1 reference

7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

1 reference

7 January 2021

The INK4a/ARF network in tumour suppression

1 reference

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7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Stabilization of c-myc protein in human glioma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

The cellular response to p53: the decision between life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Three different binding sites of Cks1 are required for p27-ubiquitin ligation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Deregulated cyclin E induces chromosome instability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Degradation of the proto-oncogene product c-Fos by the ubiquitin proteolytic system in vivo and in vitro: identification and characterization of the conjugating enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Ubiquitin/proteasome-mediated degradation of p19INK4d determines its periodic expression during the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Degradation of c-Fos by the 26S proteasome is accelerated by c-Jun and multiple protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Proteolysis and the cell cycle: with this RING I do thee destroy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

p57(Kip2) is degraded through the proteasome in osteoblasts stimulated to proliferation by transforming growth factor beta1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Cell cycle-dependent regulation of human DNA polymerase alpha-primase activity by phosphorylation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Murine double minute (MDM2) blocks p53-coactivator interaction, a new mechanism for inhibition of p53-dependent gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Both Rb and E7 are regulated by the ubiquitin proteasome pathway in HPV-containing cervical tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Nucleolar Arf sequesters Mdm2 and activates p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Retinoblastoma protein switches the E2F site from positive to negative element

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Mechanism of active transcriptional repression by the retinoblastoma protein

1 reference

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7 January 2021

The p53-mdm-2 autoregulatory feedback loop

1 reference

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7 January 2021

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.

1 reference

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7 January 2021

p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step

1 reference

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7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Viruses in human cancers

1 reference

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7 January 2021

Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

CDK-independent activation of estrogen receptor by cyclin D1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Identification of protein instability determinants in the carboxy-terminal region of c-Myb removed as a result of retroviral integration in murine monocytic leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2803%2988305-7

7 January 2021

10.1016/S0065-230X(03)88305-7

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DOI

1 reference

6 August 2017

1 reference