Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance (Q34456568)

2 August 2017

title

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance (English)

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2 August 2017

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22

Ronald M Evans

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Kristina Schoonjans

18

Kristina Schoonjans

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Shannon M Reilly

Shannon M Reilly

3

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Olivia Osborn

Olivia Osborn

5

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Alan R. Saltiel

Alan R Saltiel

20

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David A. Brenner

David A Brenner

15

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Jerrold M. Olefsky

19

Jerrold M Olefsky

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2 August 2017

Jae Myoung Suh

2

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Ruth T Yu

Ruth T Yu

14

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Bernd Schnabl

13

Bernd Schnabl

1 reference

2 August 2017

Sungsoon Fang

1

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2 August 2017

Elizabeth Yu

4

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2 August 2017

Denise Lackey

6

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2 August 2017

Eiji Yoshihara

7

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2 August 2017

Alessia Perino

8

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2 August 2017

Sandra Jacinto

9

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2 August 2017

Yelizaveta Lukasheva

10

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2 August 2017

Annette R Atkins

11

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2 August 2017

Alexander Khvat

12

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2 August 2017

Sally Coulter

16

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2 August 2017

Christopher Liddle

17

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2 August 2017

Michael Downes

21

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2 August 2017

language of work or name

English

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publication date

5 January 2015

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2 August 2017

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2 August 2017

volume

21

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2 August 2017

issue

2

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2 August 2017

page(s)

159-165

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FXR is a molecular target for the effects of vertical sleeve gastrectomy

2 August 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

6 July 2018

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6 July 2018

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Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine.

6 July 2018

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FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states

6 July 2018

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6 July 2018

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Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression

6 July 2018

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The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP.

6 July 2018

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Liver X receptor alpha is a transcriptional repressor of the uncoupling protein 1 gene and the brown fat phenotype.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

6 July 2018

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6 July 2018

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6 July 2018

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Signalling mechanisms regulating lipolysis

6 July 2018

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Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation.

6 July 2018

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p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene

6 July 2018

1 reference

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Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes.

6 July 2018

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Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR

6 July 2018

1 reference

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A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR

6 July 2018

1 reference

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Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.

6 July 2018

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Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

6 July 2018

1 reference

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Identification of a nuclear receptor for bile acids

6 July 2018

1 reference

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Identification of a nuclear receptor that is activated by farnesol metabolites

6 July 2018

1 reference

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Identification of novel transcripts in annotated genomes using RNA-Seq

6 July 2018

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Intestinal FXR-mediated FGF15 production contributes to diurnal control of hepatic bile acid synthesis in mice

27 October 2018

1 reference

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Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine

27 October 2018

1 reference

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Redundant pathways for negative feedback regulation of bile acid production

27 October 2018

1 reference

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Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4320010

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25559344

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25559344

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NM.3760

1 reference

2 August 2017

1 reference

2 August 2017

1 reference