Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy (Q34306865)

1 August 2017

title

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy (English)

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1 August 2017

7

Carlos Cordon-Cardo

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1 August 2017

Hans-Guido Wendel

1

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1 August 2017

Elisa De Stanchina

2

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1 August 2017

Jordan S Fridman

3

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1 August 2017

Abba Malina

4

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1 August 2017

Sagarika Ray

5

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1 August 2017

Scott Kogan

6

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1 August 2017

Jerry Pelletier

8

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1 August 2017

Scott W Lowe

9

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1 August 2017

language of work or name

English

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publication date

1 March 2004

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1 August 2017

number of pages

6

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inferred from page(s)

published in

Nature

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1 August 2017

volume

428

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1 August 2017

issue

6980

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1 August 2017

page(s)

332-337

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1 August 2017

cites work

The Hallmarks of Cancer

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Apoptosis: a link between cancer genetics and chemotherapy

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7 January 2021

PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy

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7 January 2021

Cellular survival: a play in three Akts

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7 January 2021

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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7 January 2021

Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia: its significance as a prognostic variable

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7 January 2021

Role of translocation in the activation and function of protein kinase B

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7 January 2021

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

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7 January 2021

Dissecting p53 tumor suppressor functions in vivo

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7 January 2021

Genetic analysis of chemoresistance in primary murine lymphomas.

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A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

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7 January 2021

Targeting mTOR signaling for cancer therapy

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7 January 2021

Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology

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7 January 2021

Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake

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7 January 2021

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

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7 January 2021

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

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7 January 2021

TOR, a central controller of cell growth

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7 January 2021

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

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7 January 2021

Translational control of the antiapoptotic function of Ras.

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7 January 2021

Global and specific translational control by rapamycin in T cells uncovered by microarrays and proteomics

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7 January 2021

Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes

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7 January 2021

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

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7 January 2021

Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases

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7 January 2021

Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse

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7 January 2021

E1A signaling to p53 involves the p19(ARF) tumor suppressor

1 reference

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7 January 2021

Identifiers

DOI

10.1038/NATURE02369

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Dimensions Publication ID

1 August 2017

1023725300

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