New insights of T cells in the pathogenesis of psoriasis (Q34043846)

30 July 2017

title

New insights of T cells in the pathogenesis of psoriasis (English)

1 reference

30 July 2017

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Yihua Cai

1

1 reference

30 July 2017

Chris Fleming

series ordinal

2

1 reference

30 July 2017

Jun Yan

series ordinal

3

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30 July 2017

publication date

18 June 2012

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Cellular and Molecular Immunology

30 July 2017

published in

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30 July 2017

volume

9

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30 July 2017

issue

4

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30 July 2017

page(s)

302-309

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Role of IL-17 in psoriasis and psoriatic arthritis

30 July 2017

cites work

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Circulating Th17, Th22, and Th1 cells are increased in psoriasis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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IL-6 signaling in psoriasis prevents immune suppression by regulatory T cells

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells

5 July 2018

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TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis

5 July 2018

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5 July 2018

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Development, cytokine profile and function of human interleukin 17-producing helper T cells

5 July 2018

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Current and future management of psoriasis

5 July 2018

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Pathogenesis and clinical features of psoriasis

5 July 2018

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Skin gammadelta T-cell functions in homeostasis and wound healing

5 July 2018

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Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

5 July 2018

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A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage

5 July 2018

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IL-17 family cytokines and the expanding diversity of effector T cell lineages

5 July 2018

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5 July 2018

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IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

5 July 2018

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Peptidoglycan: a major aetiological factor for psoriasis?

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Peptidoglycan recognition proteins (PGRPs).

5 July 2018

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Selective response of dermal Th-1 cells to 20-50 kDa streptococcal cell-wall proteins in chronic plaque psoriasis

5 July 2018

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5 July 2018

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5 July 2018

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Characterization of a T cell line bearing natural killer receptors and capable of creating psoriasis in a SCID mouse model system

5 July 2018

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Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells

5 July 2018

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5 July 2018

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5 July 2018

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The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiat

5 July 2018

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Is an epitope on keratin 17 a major target for autoreactive T lymphocytes in psoriasis?

5 July 2018

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5 July 2018

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Circulating T cells of patients with active psoriasis respond to streptococcal M-peptides sharing sequences with human epidermal keratins

5 July 2018

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Dermal injection of immunocytes induces psoriasis

5 July 2018

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CD8+ T cells in psoriatic lesions preferentially use T-cell receptor V beta 3 and/or V beta 13.1 genes

5 July 2018

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Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production.

5 July 2018

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Evidence for a streptococcal superantigen-driven process in acute guttate psoriasis.

5 July 2018

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Evidence for an antigen-specific cellular immune response in skin lesions of patients with psoriasis vulgaris

5 July 2018

1 reference

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Kinetics and regulation of human keratinocyte stem cell growth in short-term primary ex vivo culture. Cooperative growth factors from psoriatic lesional T lymphocytes stimulate proliferation among psoriatic uninvolved, but not normal, stem keratinoc

5 July 2018

1 reference

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Limited diversity of gamma delta antigen receptor genes of Thy-1+ dendritic epidermal cells

5 July 2018

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CD4 antibody treatment of severe psoriasis

5 July 2018

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Pathophysiology of Psoriasis

5 July 2018

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5 July 2018

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Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.

21 January 2018

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Enhanced proliferation and activation of peripheral blood mononuclear cells in patients with psoriasis vulgaris mediated by streptococcal antigen with bacterial DNA.

21 January 2018

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Flow cytometric characterization of lesional T cells in psoriasis: intracellular cytokine and surface antigen expression indicates an activated, memory/effector type 1 immunophenotype.

21 January 2018

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In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin.

21 January 2018

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IL-22 is required for imiquimod-induced psoriasiform skin inflammation in mice

21 January 2018

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A single intradermal injection of IFN-γ induces an inflammatory state in both non-lesional psoriatic and healthy skin

21 January 2018

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Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells

21 January 2018

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Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.

21 January 2018

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Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals

21 January 2018

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Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

21 January 2018

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Humanized anti-CD2 monoclonal antibody treatment of plaque psoriasis: efficacy and pharmacodynamic results of two randomized, double-blind, placebo-controlled studies of intravenous and subcutaneous siplizumab.

21 January 2018

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IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.15

IL-17 receptor and its functional significance in psoriatic arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.15

Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.15

Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.15

Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.15

Chimaeric CD4 monoclonal antibody in treatment of generalised pustular psoriasis

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

The Role of Streptococcal Infection in the Initiation of Guttate Psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Restricted T-cell receptor V beta gene usage in the skin of patients with guttate and chronic plaque psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

T cells involved in psoriasis vulgaris belong to the Th1 subset

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Response of murine and normal human skin to injection of allogeneic blood-derived psoriatic immunocytes: detection of T cells expressing receptors typically present on natural killer cells, including CD94, CD158, and CD161

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

CD56brightCD16(-) NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

A role for T cell-derived interleukin 22 in psoriatic skin inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Skin T cell proliferative response to M protein and other cell wall and membrane proteins of group A streptococci in chronic plaque psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Dominant lesional T cell receptor rearrangements persist in relapsing psoriasis but are absent from nonlesional skin: evidence for a stable antigen-specific pathogenic T cell response in psoriasis vulgaris

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Streptococcal throat infections and exacerbation of chronic plaque psoriasis: a prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Peripheral blood T cell responses to keratin peptides that share sequences with streptococcal M proteins are largely restricted to skin-homing CD8(+) T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Perforin expression is upregulated in the epidermis of psoriatic lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Tumor necrosis factor alpha blockade exacerbates murine psoriasis-like disease by enhancing Th17 function and decreasing expansion of Treg cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

IL-23-mediated psoriasis-like epidermal hyperplasia is dependent on IL-17A

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Efficacy and safety results from a phase III, randomized controlled trial comparing the safety and efficacy of briakinumab with etanercept and placebo in patients with moderate to severe chronic plaque psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Epidermal CCR6+ γδ T cells are major producers of IL-22 and IL-17 in a murine model of psoriasiform dermatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

A phase III, randomized, controlled trial of the fully human IL-12/23 mAb briakinumab in moderate-to-severe psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

To be 17 again--anti-interleukin-17 treatment for psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Selection of conserved TCR VDJ rearrangements in chronic psoriatic plaques indicates a common antigen in psoriasis vulgaris

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Non-M protein(s) on the cell wall and membrane of group A streptococci induce(s) IFN-gamma production by dermal CD4+ T cells in psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Cyclosporin A for psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Thy-1 Antigen-Bearing Dendritic Cells Populate Murine Epidermis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705915

12 December 2020

Identifiers

DOI

10.1038/CMI.2012.15

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference