The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo (Q24600773)

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20 January 2020

title

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo (English)

1 reference

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20 January 2020

0 references

4

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20 January 2020

author name string

Mandy J McGeachy

1

1 reference

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20 January 2020

Yi Chen

2

1 reference

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20 January 2020

Cristina M Tato

3

1 reference

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20 January 2020

Barbara Joyce-Shaikh

5

1 reference

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20 January 2020

Wendy M Blumenschein

6

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20 January 2020

Terrill K McClanahan

7

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20 January 2020

John J O'Shea

8

1 reference

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20 January 2020

Daniel J Cua

9

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20 January 2020

language of work or name

English

0 references

publication date

1 February 2009

1 reference

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20 January 2020

1 reference

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20 January 2020

volume

10

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20 January 2020

issue

3

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20 January 2020

page(s)

314-324

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Interleukin-23 drives innate and T cell-mediated intestinal inflammation

20 January 2020

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Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

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A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

7 April 2017

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

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Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

7 April 2017

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7 April 2017

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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

7 April 2017

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7 April 2017

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

7 April 2017

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Transforming growth factor-beta induces development of the T(H)17 lineage

7 April 2017

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

7 April 2017

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Helper T cell differentiation is controlled by the cell cycle

7 April 2017

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Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

7 April 2017

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

7 April 2017

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

7 April 2017

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Development, cytokine profile and function of human interleukin 17-producing helper T cells

7 April 2017

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Phenotypic and functional features of human Th17 cells

7 April 2017

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7 April 2017

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7 April 2017

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IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

7 April 2017

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Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

7 April 2017

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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27 September 2017

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Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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IL-7 promotes the transition of CD4 effectors to persistent memory cells

27 September 2017

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Interleukin 7 regulates the survival and generation of memory CD4 cells

27 September 2017

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Evolution of the T‐Cell Repertoire during the Course of Experimental Immune‐Mediated Demyelinating Diseases

27 September 2017

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Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis

27 September 2017

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Polymorphisms in the IL-12beta and IL-23R genes are associated with psoriasis of early onset in a UK cohort.

30 May 2018

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TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.

28 November 2018

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Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

28 November 2018

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Stepwise differentiation of CD4 memory T cells defined by expression of CCR7 and CD27.

28 November 2018

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IL-23 provides a limited mechanism of resistance to acute toxoplasmosis in the absence of IL-12.

28 November 2018

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Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses

28 November 2018

1 reference

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Understanding the IL-23-IL-17 immune pathway

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19182808

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19182808

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19182808

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.1698

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19182808%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19182808%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

19182808

2 references