The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens (Q33928484)

30 July 2017

title

The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens (English)

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30 July 2017

6

Rafi Ahmed

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30 July 2017

7

Jerome A Zack

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30 July 2017

Scott G Kitchen

1

1 reference

30 July 2017

Jason K Whitmire

2

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30 July 2017

Nicole R Jones

3

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30 July 2017

Zoran Galic

4

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30 July 2017

Christina M R Kitchen

5

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30 July 2017

language of work or name

English

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publication date

24 February 2005

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

102

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30 July 2017

issue

10

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30 July 2017

page(s)

3794-3799

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CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

The CD8 population in CD4-deficient mice is heavily contaminated with MHC class II-restricted T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Persistent HIV-1 infection of natural killer cells in patients receiving highly active antiretroviral therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Activated peripheral CD8 lymphocytes express CD4 in vivo and are targets for infection by human immunodeficiency virus type 1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

The role of gamma interferon in antimicrobial immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Mast cells/basophils in the peripheral blood of allergic individuals who are HIV-1 susceptible due to their surface expression of CD4 and the chemokine receptors CCR3, CCR5, and CXCR4.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Cutting edge: antigen-independent CD8 T cell proliferation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Interleukin 16: implications for CD4 functions and HIV-1 progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Extrathymic CD4/CD8 double positive T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

CD40-Mediated induction of CD4 and CXCR4 on B lymphocytes correlates with restricted susceptibility to human immunodeficiency virus type 1 infection: potential role of B lymphocytes as a viral reservoir

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Respiratory mucosal immunization with reovirus serotype 1/L stimulates virus-specific humoral and cellular immune responses, including double-positive (CD4(+)/CD8(+)) T cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Costimulation of naive CD8(+) lymphocytes induces CD4 expression and allows human immunodeficiency virus type 1 infection.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Productive infection of neonatal CD8+ T lymphocytes by HIV-1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Activation of CD8+ T lymphocytes through the T cell receptor turns on CD4 gene expression: implications for HIV pathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

CD4 and signal transduction.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Emergence of double-positive CD4/CD8 cells from adult peripheral blood mononuclear cells infected with human T cell leukemia virus type I (HTLV-I).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Human eosinophils express CD4 protein and bind human immunodeficiency virus 1 gp120

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Induction of CD4 and susceptibility to HIV-1 infection in human CD8+ T lymphocytes by human herpesvirus 6

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Infection of brain microglial cells by human immunodeficiency virus type 1 is CD4 dependent

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Response differences between human CD4(+) and CD8(+) T-cells during CD28 costimulation: implications for immune cell-based therapies and studies related to the expansion of double-positive T-cells during aging

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406603102

Development of a transient CD4(+)CD8(+) T cell subset in the cervical lymph nodes following intratracheal instillation with an adenovirus vector.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406603102

Upregulation of CD4 on CD8+ T cells: CD4dimCD8bright T cells constitute an activated phenotype of CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406603102

Activation of CD8 T cells induces expression of CD4, which functions as a chemotactic receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406603102

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406603102

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406603102

Expression of CD4 on human peripheral blood neutrophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406603102

Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406603102

Functional characterization of MHC class II-restricted CD8+CD4- and CD8-CD4- T cell responses to infection in CD4-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406603102

Early programming of T cell populations responding to bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406603102

Expression of CD4 by human hematopoietic progenitors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=553300

Dynamic programming of CD8+ T lymphocyte responses

29 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/15731353

12 December 2020

Detection of surface and cytoplasmic CD4 on blood monocytes from normal and HIV-1 infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/15731353

12 December 2020

CD4 T lymphocytes are primed to express Fas ligand by CD4 cross-linking and to contribute to CD8 T-cell apoptosis via Fas/FasL death signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15731353

12 December 2020

Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor-alpha secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/15731353

12 December 2020

Phenotypic and functional evidence for the expression of CD4 by hematopoietic stem cells isolated from human fetal liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/15731353

12 December 2020

Monocytes express Fas ligand upon CD4 cross-linking and induce CD4+ T cells apoptosis: a possible mechanism of bystander cell death in HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15731353

12 December 2020

Identifiers

DOI

10.1073/PNAS.0406603102

1 reference

30 July 2017

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1 reference

30 July 2017

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