Similarities and differences in CD4+ and CD8+ effector and memory T cell generation (Q35207085)

7 August 2017

1 reference

title

Similarities and differences in CD4+ and CD8+ effector and memory T cell generation (English)

1 reference

7 August 2017

2

Rafi Ahmed

1 reference

7 August 2017

Robert A Seder

1

1 reference

7 August 2017

language of work or name

English

0 references

publication date

1 September 2003

1 reference

7 August 2017

1 reference

7 August 2017

volume

4

1 reference

7 August 2017

issue

9

1 reference

7 August 2017

page(s)

835-842

1 reference

Cytokines induce the development of functionally heterogeneous T helper cell subsets

7 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Cutting edge: antigen-independent CD8 T cell proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Continued antigen stimulation is not required during CD4(+) T cell clonal expansion

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

T cell fitness determined by signal strength

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Progressive differentiation and selection of the fittest in the immune response

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

The duration of antigenic stimulation determines the fate of naive and effector T cells.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Dynamic programming of CD8+ T lymphocyte responses

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Two distinct stages in the transition from naive CD4 T cells to effectors, early antigen-dependent and late cytokine-driven expansion and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Distinct lineages of T(H)1 cells have differential capacities for memory cell generation in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Molecular and functional profiling of memory CD8 T cell differentiation.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Signaling and transcription in T helper development

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

A novel transcription factor, T-bet, directs Th1 lineage commitment

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Cutting edge: CD4 and CD8 T cells are intrinsically different in their proliferative responses

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Costimulation in antiviral immunity: differential requirements for CD4(+) and CD8(+) T cell responses

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Cutting edge: virus-specific CD4+ memory T cells in nonlymphoid tissues express a highly activated phenotype

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Clonal Expansions in Acute EBV Infection Are Detectable in the CD8 and not the CD4 Subset and Persist with a Variable CD45 Phenotype

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

The potency and durability of DNA- and protein-based vaccines against Leishmania major evaluated using low-dose, intradermal challenge.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Comparison of different delivery systems of vaccination for the induction of protection against tuberculosis in mice

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Characterization of the memory/activated T cells that mediate the long-lived host response against tuberculosis after bacillus Calmette-Guérin or DNA vaccination.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Persistence and turnover of antigen-specific CD4 T cells during chronic tuberculosis infection in the mouse.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Influence of effector molecules on the CD8(+) T cell response to infection

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

A role for CD40 expression on CD8+ T cells in the generation of CD8+ T cell memory

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Single-cell analysis by RT-PCR reveals differential expression of multiple type 1 and 2 cytokine genes among cells within polarized CD4+ T cell populations

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Heterogeneity of single cell cytokine gene expression in clonal T cell populations

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Antigen-specific T helper cell function: differential cytokine expression in primary and memory responses

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Heterogeneity of the memory CD4 T cell response: persisting effectors and resting memory T cells.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

CD4 effector T cell subsets in the response to influenza: heterogeneity, migration, and function

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Molecular mechanisms of activated T cell death in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

The mechanism and significance of deletion of parasite-specific CD4(+) T cells in malaria infection

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Interferon gamma is required for activation-induced death of T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Visualizing the generation of memory CD4 T cells in the whole body

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Preferential localization of effector memory cells in nonlymphoid tissue

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Immediate early effector functions of virus-specific CD8+CCR7+ memory cells in humans defined by HLA and CC chemokine ligand 19 tetramers

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Lineage relationship and protective immunity of memory CD8 T cell subsets

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Cutting edge: CCR7+ and CCR7- memory T cells do not differ in immediate effector cell function.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Rules of chemokine receptor association with T cell polarization in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Skewed maturation of memory HIV-specific CD8 T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Withdrawal of stimulation may initiate the transition of effector to memory CD4 cells

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Programmed contraction of CD8(+) T cells after infection.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Clonal selection, clonal senescence, and clonal succession: the evolution of the T cell response to infection with a persistent virus

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

CD4(+) T cell effectors can become memory cells with high efficiency and without further division.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

The repertoires of circulating human CD8(+) central and effector memory T cell subsets are largely distinct

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

https://api.crossref.org/works/10.1038%2FNI969

1 reference

7 January 2021

Gamma chain required for naïve CD4+ T cell survival but not for antigen proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Independent regulation of lymphocytic choriomeningitis virus-specific T cell memory pools: relative stability of CD4 memory under conditions of CD8 memory T cell loss.

1 reference

https://api.crossref.org/works/10.1038%2FNI969

7 January 2021

Identifiers

DOI

10.1038/NI969

1 reference

Dimensions Publication ID

7 August 2017

1020829945

0 references

1 reference