Watching worms whither: modeling neurodegeneration in C. elegans (Q33837857)

29 July 2017

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title

Watching worms whither: modeling neurodegeneration in C. elegans (English)

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29 July 2017

main subject

Caenorhabditis elegans

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1 reference

Atsushi Ebata

5

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Benjamin Wolozin

object named as

Benjamin Wolozin

1

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author name string

Christopher Gabel

2

1 reference

29 July 2017

Andrew Ferree

3

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29 July 2017

Maria Guillily

4

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29 July 2017

publication date

1 January 2011

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Progress in Molecular Biology and Translational Science

29 July 2017

published in

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29 July 2017

volume

100

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29 July 2017

page(s)

499-514

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TAR DNA-binding protein 43 in neurodegenerative disease

29 July 2017

cites work

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Calcium and cyclic AMP promote axonal regeneration in Caenorhabditis elegans and require DLK-1 kinase

4 July 2018

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Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

4 July 2018

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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

4 July 2018

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Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/alpha-synuclein complex by Hip

4 July 2018

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Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models

4 July 2018

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The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration

4 July 2018

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Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease

4 July 2018

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LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans

4 July 2018

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Rapid selection of cyclic peptides that reduce alpha-synuclein toxicity in yeast and animal models

4 July 2018

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SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans

4 July 2018

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Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth

4 July 2018

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Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

4 July 2018

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Axon regeneration requires a conserved MAP kinase pathway.

4 July 2018

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Application of a C. elegans dopamine neuron degeneration assay for the validation of potential Parkinson's disease genes.

4 July 2018

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

4 July 2018

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Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity

4 July 2018

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Zeroing in on LRRK2-linked pathogenic mechanisms in Parkinson's disease.

4 July 2018

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Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

4 July 2018

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Sub-cellular precision on-chip small-animal immobilization, multi-photon imaging and femtosecond-laser manipulation

4 July 2018

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Femtosecond laser nanoaxotomy lab-on-a-chip for in vivo nerve regeneration studies.

4 July 2018

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C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging

4 July 2018

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Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans

4 July 2018

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Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model

4 July 2018

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The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis

4 July 2018

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Proteomics of Caenorhabditis elegans over-expressing human alpha-synuclein analyzed by fluorogenic derivatization-liquid chromatography/tandem mass spectrometry: identification of actin and several ribosomal proteins as negative markers at early Par

4 July 2018

1 reference

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Caenorhabditis elegans neuronal regeneration is influenced by life stage, ephrin signaling, and synaptic branching.

4 July 2018

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Assembly, trafficking and function of gamma-secretase

4 July 2018

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Caenorhabditis elegans MPP+ model of Parkinson's disease for high-throughput drug screenings

4 July 2018

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Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

4 July 2018

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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

4 July 2018

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Identification of gene expression changes in transgenic C. elegans overexpressing human alpha-synuclein

4 July 2018

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The role of the AFD neuron in C. elegans thermotaxis analyzed using femtosecond laser ablation

4 July 2018

1 reference

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4 July 2018

1 reference

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Regeneration of the adult central nervous system

4 July 2018

1 reference

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Tau phosphorylation: physiological and pathological consequences

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140532

Neurosurgery: functional regeneration after laser axotomy.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140532

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

4 July 2018

1 reference

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Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model

4 July 2018

1 reference

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Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

4 July 2018

1 reference

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The Caenorhabditis elegans dopaminergic system: opportunities for insights into dopamine transport and neurodegeneration

4 July 2018

1 reference

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Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans

4 July 2018

1 reference

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C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway

4 July 2018

1 reference

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Presenilins: molecular switches between proteolysis and signal transduction

4 July 2018

1 reference

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Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

4 July 2018

1 reference

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Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans

4 July 2018

1 reference

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Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

4 July 2018

1 reference

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Global microRNA expression profiling of Caenorhabditis elegans Parkinson's disease models

4 July 2018

1 reference

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Evaluation of pesticide toxicities with differing mechanisms using Caenorhabditis elegans.

29 October 2018

1 reference

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Dopamine neuron degeneration induced by MPP+ is independent of CED-4 pathway in Caenorhabditis elegans

29 October 2018

1 reference

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A microfabricated array of clamps for immobilizing and imaging C. elegans

29 October 2018

1 reference

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Decreased insulin-receptor signaling promotes the autophagic degradation of beta-amyloid peptide in C. elegans

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140532

SUT-1 enables tau-induced neurotoxicity in C. elegans

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140532

LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140532

Familial Parkinson mutant alpha-synuclein causes dopamine neuron dysfunction in transgenic Caenorhabditis elegans

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140532

Torsin-mediated protection from cellular stress in the dopaminergic neurons of Caenorhabditis elegans.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140532

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140532

Membrane topology of the C. elegans SEL-12 presenilin

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21377635

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Proteomic identification of proteins specifically oxidized in Caenorhabditis elegans expressing human Abeta(1-42): implications for Alzheimer's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21377635

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of neuroprotective compounds of caenorhabditis elegans dopaminergic neurons against 6-OHDA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21377635

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/B978-0-12-384878-9.00015-7

1 reference

29 July 2017

1 reference

29 July 2017

1 reference