Context-dependent pharmacology exhibited by negative allosteric modulators of metabotropic glutamate receptor 7 (Q33520184)

27 July 2017

title

Context-dependent pharmacology exhibited by negative allosteric modulators of metabotropic glutamate receptor 7 (English)

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27 July 2017

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1

Colleen M Niswender

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27 July 2017

10

P Jeffrey Conn

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27 July 2017

8

Darren Orton

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27 July 2017

4

Jennifer E Ayala

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27 July 2017

6

Richard Williams

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27 July 2017

Kari A Johnson

2

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27 July 2017

Nicole R Miller

3

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27 July 2017

Qingwei Luo

5

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27 July 2017

Samir Saleh

7

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27 July 2017

C David Weaver

9

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27 July 2017

publication date

21 December 2009

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27 July 2017

published in

Molecular Pharmacology

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27 July 2017

volume

77

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27 July 2017

issue

3

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27 July 2017

page(s)

459-468

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Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

27 July 2017

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21 June 2018

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21 June 2018

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Group III mGluR regulation of synaptic transmission at the SC-CA1 synapse is developmentally regulated

21 June 2018

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A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors

21 June 2018

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21 June 2018

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In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists.

21 June 2018

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MacMARCKS interacts with the metabotropic glutamate receptor type 7 and modulates G protein-mediated constitutive inhibition of calcium channels

21 June 2018

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Functional Selectivity and Classical Concepts of Quantitative Pharmacology

21 June 2018

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New concepts in drug discovery: collateral efficacy and permissive antagonism

21 June 2018

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New therapeutic frontiers for metabotropic glutamate receptors

21 June 2018

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A close structural analog of 2-methyl-6-(phenylethynyl)-pyridine acts as a neutral allosteric site ligand on metabotropic glutamate receptor subtype 5 and blocks the effects of multiple allosteric modulators

21 June 2018

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Allosteric potentiators of metabotropic glutamate receptor subtype 5 have differential effects on different signaling pathways in cortical astrocytes

21 June 2018

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G-protein-coupled receptor oligomerization and its potential for drug discovery

21 June 2018

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G-protein-coupled receptors for neurotransmitter amino acids: C-terminal tails, crowded signalosomes

21 June 2018

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Regulation of mglu(7) receptors by proteins that interact with the intracellular C-terminus

21 June 2018

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21 June 2018

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Cloning and characterization of alternative mRNA forms for the rat metabotropic glutamate receptors mGluR7 and mGluR8

21 June 2018

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Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells

21 June 2018

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Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus

21 June 2018

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Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

21 June 2018

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Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid-sensitive class of metabotropic glutamate receptors

21 June 2018

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Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus

21 June 2018

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Isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists

21 June 2018

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Presynaptic metabotropic glutamate receptors regulate glutamatergic input to dopamine neurons in the ventral tegmental area

31 October 2018

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Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2.

31 October 2018

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mGluR7 is a metaplastic switch controlling bidirectional plasticity of feedforward inhibition

31 October 2018

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mGluR7-like metabotropic glutamate receptors inhibit NMDA-mediated excitotoxicity in cultured mouse cerebellar granule neurons.

31 October 2018

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Metabotropic glutamate receptors activate G-protein-coupled inwardly rectifying potassium channels in Xenopus oocytes

31 October 2018

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Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20026717

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/MOL.109.058768

1 reference

27 July 2017

1 reference

27 July 2017

1 reference