MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells (Q28593914)

31 January 2017

title

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells (English)

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MAD2 mitotic arrest deficient-like 1

31 January 2017

main subject

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GOA release 2020-03-11

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L. S. Michel

1

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31 January 2017

V. Liberal

2

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31 January 2017

A. Chatterjee

3

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31 January 2017

R. Kirchwegger

4

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31 January 2017

B. Pasche

5

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31 January 2017

W. Gerald

6

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31 January 2017

M. Dobles

7

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31 January 2017

P. K. Sorger

8

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31 January 2017

V. V. Murty

9

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31 January 2017

R. Benezra

10

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31 January 2017

language of work or name

English

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publication date

18 January 2001

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31 January 2017

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31 January 2017

volume

409

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31 January 2017

issue

6818

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31 January 2017

page(s)

355–359

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Identification of a human mitotic checkpoint gene: hsMAD2

31 January 2017

cites work

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The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

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Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila

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Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

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Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis

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Genetic instability in colorectal cancers

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Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

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MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity

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The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

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7 January 2021

Mad2 transiently associates with an APC/p55Cdc complex during mitosis

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Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

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7 January 2021

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Cdc28 activates exit from mitosis in budding yeast.

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Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast

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7 January 2021

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7 January 2021

Identification of frequent impairment of the mitotic checkpoint and molecular analysis of the mitotic checkpoint genes, hsMAD2 and p55CDC, in human lung cancers

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7 January 2021

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7 January 2021

Map location and gene structure of the Homo sapiens mitotic arrest deficient 2 (MAD2L1) gene at 4q27

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7 January 2021

Genetic alterations in hepatocellular carcinomas: association between loss of chromosome 4q and p53 gene mutations

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7 January 2021

Recurring chromosome abnormalities in Hodgkin's disease

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7 January 2021