Genetic alterations in hepatocellular carcinomas: association between loss of chromosome 4q and p53 gene mutations (Q41910235)

14 October 2017

Genetic alterations in hepatocellular carcinomas: association between loss of chromosome 4q and p53 gene mutations (English)

1 reference

14 October 2017

Rashid A

1

1 reference

14 October 2017

Wang JS

2

1 reference

14 October 2017

Qian GS

3

1 reference

14 October 2017

Lu BX

4

1 reference

14 October 2017

Hamilton SR

5

1 reference

14 October 2017

Groopman JD

6

1 reference

14 October 2017

language of work or name

English

0 references

publication date

1 April 1999

1 reference

British Journal of Cancer

14 October 2017

1 reference

14 October 2017

80

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14 October 2017

1-2

1 reference

14 October 2017

59-66

1 reference

Allelotype analysis of adenocarcinoma of the gastric cardia

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Genetic alterations in sporadic and Crohn's-associated adenocarcinomas of the small intestine.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Frequent loss of chromosome 8p in hepatitis B virus-positive hepatocellular carcinomas from China.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

PTPN13, a fas-associated protein tyrosine phosphatase, is located on the long arm of chromosome 4 at band q21.3

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Molecular biomarkers for aflatoxins: from adducts to gene mutations to human liver cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Simultaneous assessment of loss of heterozygosity at multiple microsatellite loci using semi-automated fluorescence-based detection: subregional mapping of chromosome 4 in cervical carcinoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Mutant p53 but not hepatitis B virus X protein is present in hepatitis B virus-related human hepatocellular carcinoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

High prevalence of mutations at codon 249 of the p53 gene in hepatocellular carcinomas from Senegal

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Hepatocarcinoma-specific mutant p53-249ser induces mitotic activity but has no effect on transforming growth factor beta 1-mediated apoptosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Hepatitis B and C viruses in the development of hepatocellular carcinoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Functional inactivation but not structural mutation of p53 causes liver cancer.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Accumulation of genetic changes during development and progression of hepatocellular carcinoma: Loss of heterozygosity on chromosome arm Ip occurs at an early stage of hepatocarcinogenesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Evidence for the presence of two tumour-suppressor genes for hepatocellular carcinoma on chromosome 13q

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Codon 249 mutation of the p53 gene is a rare event in hepatocellular carcinomas from ethnic Chinese in Singapore

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Introduction of a murine p53 mutation corresponding to human codon 249 into a murine hepatocyte cell line results in growth advantage, but not in transformation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

A gene that regulates DNA replication in response to DNA damage is located on human chromosome 4q.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Loss of alleles from the distal short arm of chromosome 1 occurs late in melanoma tumor progression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Loss of heterozygosity suggests tumor suppressor gene responsible for primary hepatocellular carcinoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Neuroblastoma consensus deletion maps to 1p36.1-2.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

GST1 gene deletion determined by polymerase chain reaction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Frequent loss of heterozygosity on chromosomes 16 and 4 in human hepatocellular carcinoma.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Mutational hot spot in the p53 gene in human hepatocellular carcinomas

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Interstitial chromosomal deletion within 4q11-q13 in a human hepatoma cell line

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Allelotype study of primary hepatocellular carcinoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Abnormalities of chromosome 1 and loss of heterozygosity on 1p in primary hepatomas

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Mutations in the BRCA2 gene in hepatocellular carcinomas.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Deletion of the E-cadherin gene in hepatitis B virus-positive Chinese hepatocellular carcinomas

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Loss of heterozygosity and analysis of mutation of p53 in hepatocellular carcinoma

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Concerted nonsyntenic allelic losses in hyperploid hepatocellular carcinoma as determined by a high-resolution allelotype

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Comprehensive allelotyping of human hepatocellular carcinoma

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2362990

Deletions of chromosome 13q, mutations in Retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma

2 December 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Frequent genetic alterations at the distal region of chromosome 1p in human hepatocellular carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Allelotype analysis of cervical carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Wet autoclave pretreatment for antigen retrieval in diagnostic immunohistochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Deletions in human chromosome arms 11p and 13q in primary hepatocellular carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Human colorectal cancer: high frequency of deletions at chromosome 1p35

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Frequent somatic imbalance of marker alleles for chromosome 1 in human primary breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Integrity of p53 in hepatitis B x antigen-positive and -negative hepatocellular carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Deletion mapping of chromosome 4 in head and neck squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Localization of the cell death genes CPP32 and Mch-2 to human Chromosome 4q

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Loss of somatic heterozygosity in hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Frequent loss of heterozygosity for loci on chromosome 8p in hepatocellular carcinoma, colorectal cancer, and lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Recurring chromosome abnormalities in Hodgkin's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Genotype and phenotype of glutathione S-transferase class mu isoenzymes mu and psi in lung cancer patients and controls

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Frequent loss of heterozygosity on chromosome 22 in hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

p53 gene mutations and 17p allelic deletions in hepatocellular carcinoma from Japan

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Allelotype and loss of heterozygosity of p53 in primary and recurrent hepatocellular carcinomas. A study of 150 patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of China

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

p53 protein accumulation in European hepatocellular carcinoma is not always dependent on p53 gene mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Distinct regions of allelic loss on chromosome 4 in human primary bladder carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

The clinical significance of p53 gene mutation in hepatocellular carcinomas from Japan

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Low incidence of p53 mutations in European hepatocellular carcinomas with heterogeneous mutation as a rare event

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Allelic loss on chromosomes 4q and 16q in hepatocellular carcinoma: Association with elevated alpha-fetoprotein production

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Trisomy 1 and 8 occur frequently in hepatocellular carcinoma but not in liver cell adenoma and focal nodular hyperplasia. A fluorescence in situ hybridization study

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Chromosome 1p aberrations are frequent in human primary hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Loss of heterozygosity in chromosome 4q12-q13 in hepatocellular carcinoma in southern African blacks

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Allelotype analysis of esophageal adenocarcinomas: evidence for the involvement of sequences on the long arm of chromosome 4

1 reference

https://pubmed.ncbi.nlm.nih.gov/10389978

12 December 2020

Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690321

7 January 2021

inferred from DOI database lookup

p53 mutation in hepatocellular carcinoma after aflatoxin exposure

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJC.6690321

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.BJC.6690321

1 reference

14 October 2017

1 reference

14 October 2017

PubMed publication ID

10389978

1 reference