De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase (Q28591006)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12867411%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12867411%20AND%20SRC:MED&resulttype=core&format=json

Cytochrome P450, family 2, subfamily r, polypeptide 1

5 November 2019

main subject

vitamin D

0 references

1 reference

GOA release 2020-03-11

author

David Mangelsdorf

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12867411%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

David W. Russell

4

1 reference

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5 November 2019

author name string

Jeffrey B Cheng

1

1 reference

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5 November 2019

Daniel L Motola

2

1 reference

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5 November 2019

language of work or name

English

0 references

publication date

16 July 2003

1 reference

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Journal of Biological Chemistry

5 November 2019

published in

2 references

31 January 2017

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5 November 2019

volume

278

2 references

31 January 2017

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5 November 2019

issue

39

2 references

31 January 2017

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5 November 2019

page(s)

38084-38093

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The enzymes, regulation, and genetics of bile acid synthesis

5 November 2019

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Vitamin D receptor as an intestinal bile acid sensor

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Transfected human liver cytochrome P-450 hydroxylates vitamin D analogs at different side-chain positions

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Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

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Molecular cloning of cDNA for vitamin D3 25-hydroxylase from rat liver mitochondria

17 March 2017

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A cDNA encoding a rat mitochondrial cytochrome P450 catalyzing both the 26-hydroxylation of cholesterol and 25-hydroxylation of vitamin D3: gonadotropic regulation of the cognate mRNA in ovaries

17 March 2017

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Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis

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Cloning and expression of cDNA encoding 25-hydroxyvitamin D3 24-hydroxylase

17 March 2017

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Comparison of P450s from human and fugu: 420 million years of vertebrate P450 evolution

17 March 2017

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Carbohydrate Metabolism: Glycogen Phosphorylase and the Work of Carl F. and Gerty T.Cori. 1928-1943.

29 September 2017

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Enhancement of VDR-mediated transcription by phosphorylation: correlation with increased interaction between the VDR and DRIP205, a subunit of the VDR-interacting protein coactivator complex

29 September 2017

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A possible meiotic function of the peculiar patterns of gene expression in mammalian spermatogenic cells

29 September 2017

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Current understanding of the molecular actions of vitamin D.

29 September 2017

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P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

29 September 2017

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29 September 2017

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Molecular cloning of 25-hydroxyvitamin D-3 24-hydroxylase (Cyp-24) from mouse kidney: its inducibility by vitamin D-3

21 January 2018

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Chromosomal receptor for a vitamin D metabolite

29 September 2017

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Isolation and identification of 1,25-dihydroxycholecalciferol. A metabolite of vitamin D active in intestine

29 September 2017

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29 September 2017

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The role of the liver in the metabolism of vitamin D.

29 September 2017

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29 September 2017

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Impact of virus infection on host cell protein synthesis

29 September 2017

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Molecular cloning of complementary DNA encoding the avian receptor for vitamin D.

29 September 2017

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29 September 2017

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Assay and properties of a mitochondrial 25-hydroxylase active on vitamine D3

29 September 2017

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Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene

29 September 2017

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Subcellular location of rat liver calciferol-25-hydroxylase

3 June 2018

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25-Hydroxylase activity in subcellular fractions from human liver. Evidence for different rates of mitochondrial hydroxylation of vitamin D2 and D3.

3 June 2018

1 reference

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25-Hydroxylation of vitamin D3 by a cytochrome P-450 from rabbit liver mitochondria

3 June 2018

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25‐hydroxylation of 1α‐hydroxyvitamin D3 in vivo and in perfused rat liver

3 June 2018

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Interaction between vitamin D receptor and vitamin D ligands: two-dimensional alanine scanning mutational analysis.

3 June 2018

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21 January 2018

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Cloning and nucleotide sequence of a bacterial cytochrome P-450VD25 gene encoding vitamin D-3 25-hydroxylase

21 January 2018

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Sequence alignments, variabilities, and vagaries.

21 January 2018

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Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.

27 November 2018

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Unique Biosynthesis by Kidney of a Biologically Active Vitamin D Metabolite

27 November 2018

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25-hydroxylation of C27-steroids and vitamin D3 by a constitutive cytochrome P-450 from rat liver microsomes

21 January 2018

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12 December 2020

The Association of a Metabolite of Vitamin D3 with Intestinal Mucosa Chromatin in Vivo

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25-Hydroxylation of 1 alpha-hydroxyvitamin D-3 in rat and human liver

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12 December 2020

A close family resemblance: the importance of structure in understanding cytochromes P450

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12 December 2020

Identifiers

DOI

10.1074/JBC.M307028200

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12867411%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

2 references

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5 November 2019

2 references