Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria (Q28573343)

31 January 2017

title

Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria (English)

1 reference

31 January 2017

1 reference

1 reference

reactive oxygen species

1 reference

0 references

1 reference

Seiji Nakamura

1

1 reference

31 January 2017

Toshinari Takamura

2

1 reference

31 January 2017

Naoto Matsuzawa-Nagata

3

1 reference

31 January 2017

Hiroaki Takayama

4

1 reference

31 January 2017

Hirofumi Misu

5

1 reference

31 January 2017

Hiroyo Noda

6

1 reference

31 January 2017

Satoko Nabemoto

7

1 reference

31 January 2017

Seiichiro Kurita

8

1 reference

31 January 2017

Tsuguhito Ota

9

1 reference

31 January 2017

Hitoshi Ando

10

1 reference

31 January 2017

Ken-Ichi Miyamoto

11

1 reference

31 January 2017

Shuichi Kaneko

12

1 reference

31 January 2017

language of work or name

English

0 references

publication date

29 May 2009

1 reference

Journal of Biological Chemistry

31 January 2017

published in

1 reference

31 January 2017

volume

284

1 reference

31 January 2017

issue

22

1 reference

31 January 2017

page(s)

14809–14818

1 reference

Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism

31 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Biochemistry and molecular cell biology of diabetic complications

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Insulin signalling and the regulation of glucose and lipid metabolism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Signal transduction by the JNK group of MAP kinases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Metabolic aspects of peroxisomal beta-oxidation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Increased oxidative stress in obesity and its impact on metabolic syndrome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

23 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Reactive oxygen species have a causal role in multiple forms of insulin resistance

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

A central role for JNK in obesity and insulin resistance

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

NADPH oxidase in the liver: defensive, offensive, or fibrogenic?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Oxidative stress and the JNK pathway as a potential therapeutic target for diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Transcriptional and translational control in the Mammalian unfolded protein response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Role of fatty acids in the pathogenesis of insulin resistance and NIDDM.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

1,2-Diacylglycerol and ceramide levels in insulin-resistant tissues of the rat in vivo.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685662

Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet.

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M901488200

SREBPs suppress IRS-2-mediated insulin signalling in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M901488200

Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M901488200

Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M901488200

Modulation of the JNK pathway in liver affects insulin resistance status

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M901488200

Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M901488200

Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M901488200

A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M901488200

Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19332540

12 December 2020

Liver steatosis, but not fibrosis, is associated with insulin resistance in nonalcoholic fatty liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19332540

12 December 2020

It's what you do with the fat that matters!

1 reference

https://pubmed.ncbi.nlm.nih.gov/19332540

12 December 2020

Sodium palmitate induces partial mitochondrial uncoupling and reactive oxygen species in rat pancreatic islets in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/19332540

12 December 2020

Identifiers

DOI

10.1074/JBC.M901488200

1 reference

1 reference

1 reference

1 reference