Advances in umbilical cord blood manipulation-from niche to bedside (Q26824305)

Anthony E. Boitano

2

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Colleen S. Delaney

3

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Elizabeth J. Shpall

4

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John E. Wagner

5

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language of work or name

1 reference

March 2015

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Nature Reviews Clinical Oncology

published in

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volume

12

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issue

3

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page(s)

163-74

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Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells

cites work

1 reference

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A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

7 April 2017

1 reference

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A perivascular origin for mesenchymal stem cells in multiple human organs

7 April 2017

1 reference

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Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1

7 April 2017

1 reference

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Human mesenchymal stem cells modulate allogeneic immune cell responses

7 April 2017

1 reference

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Mesenchymal stem cells as trophic mediators

7 April 2017

1 reference

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Marrow stromal cells as stem cells for nonhematopoietic tissues

7 April 2017

1 reference

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Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment

22 April 2017

1 reference

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Inhibition of DPP4/CD26 and dmPGE₂ treatment enhances engraftment of mouse bone marrow hematopoietic stem cells

28 September 2017

1 reference

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Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation

28 September 2017

1 reference

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Complement fragment 3a priming of umbilical cord blood progenitors: safety profile.

28 September 2017

1 reference

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Umbilical cord blood transplantation: the first 25 years and beyond

28 September 2017

1 reference

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Indications and outcomes of reduced-toxicity hematopoietic stem cell transplantation in adult patients with hematological malignancies

28 September 2017

1 reference

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Nampt expression increases during osteogenic differentiation of multi- and omnipotent progenitors

28 September 2017

1 reference

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Innate immunity as orchestrator of bone marrow homing for hematopoietic stem/progenitor cells

28 September 2017

1 reference

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In vivo DPP-4 inhibition to enhance engraftment of single-unit cord blood transplants in adults with hematological malignancies

28 September 2017

1 reference

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Cord-blood engraftment with ex vivo mesenchymal-cell coculture

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Double unit grafts successfully extend the application of umbilical cord blood transplantation in adults with acute leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Peripheral-blood stem cells versus bone marrow from unrelated donors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Notch signalling in cancer progression and bone metastasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Factors predicting single-unit predominance after double umbilical cord blood transplantation

28 September 2017

1 reference

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Donor-specific anti-HLA antibodies predict outcome in double umbilical cord blood transplantation.

28 September 2017

1 reference

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Cost effectiveness of cord blood versus bone marrow and peripheral blood stem cells

28 September 2017

1 reference

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Notch signaling: simplicity in design, versatility in function

28 September 2017

1 reference

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Cord blood-derived hematopoietic stem/progenitor cells: current challenges in engraftment, infection, and ex vivo expansion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Sirt1's systemic protective roles and its promise as a target in antiaging medicine

28 September 2017

1 reference

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How I treat: the selection and acquisition of unrelated cord blood grafts

28 September 2017

1 reference

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Influence of infused cell dose and HLA match on engraftment after double-unit cord blood allografts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

The intra-bone marrow injection of cord blood cells extends the possibility of transplantation to the majority of patients with malignant hematopoietic diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Allogeneic hematopoietic cell transplantation for hematologic malignancy: relative risks and benefits of double umbilical cord blood

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Mesenchymal stem cells: Mechanisms of immunomodulation and homing

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Perivascular ancestors of adult multipotent stem cells

28 September 2017

1 reference

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Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Relapse risk after umbilical cord blood transplantation: enhanced graft-versus-leukemia effect in recipients of 2 units

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Costs of pediatric allogeneic hematopoietic-cell transplantation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Notch signaling and the bone marrow hematopoietic stem cell niche

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

NAD(+), sirtuins, and cardiovascular disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Intra-BM injection to enhance engraftment after myeloablative umbilical cord blood transplantation with two partially HLA-matched units.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: a phase I/II clinical trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Preinfusion variables predict the predominant unit in the setting of reduced-intensity double cord blood transplantation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis

28 September 2017

1 reference

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Enhanced T-cell reconstitution by hematopoietic progenitors expanded ex vivo using the Notch ligand Delta1

28 September 2017

1 reference

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Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells

28 September 2017

1 reference

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Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors

28 September 2017

1 reference

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Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

28 September 2017

1 reference

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Homing and engraftment potential of Sca-1(+)lin(-) cells fractionated on the basis of adhesion molecule expression and position in cell cycle

28 September 2017

1 reference

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The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood.

28 September 2017

1 reference

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Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins

28 September 2017

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Neutropenia caused by copper deficiency: possible mechanisms of action.

28 September 2017

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Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells

28 September 2017

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Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430198

Observations on the anemia and neutropenia of human copper deficiency

28 September 2017

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Conditions controlling the proliferation of haemopoietic stem cells in vitro

28 September 2017

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28 September 2017

1 reference

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Should double cord blood transplants be the preferred choice when a sibling donor is unavailable?

31 May 2018

1 reference

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Defective engraftment of C3aR-/- hematopoietic stem progenitor cells shows a novel role of the C3a-C3aR axis in bone marrow homing

31 May 2018

1 reference

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Superior ex vivo cord blood expansion following co-culture with bone marrow-derived mesenchymal stem cells

31 May 2018

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Cellular copper content modulates differentiation and self-renewal in cultures of cord blood-derived CD34+ cells

31 May 2018

1 reference

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A human homologue of the Drosophila developmental gene, Notch, is expressed in CD34+ hematopoietic precursors.

31 May 2018

1 reference

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Prostaglandin-mediated enhancement of erythroid colonies by marrow stromal cells (MSC)

31 May 2018

1 reference

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Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia

31 May 2018

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High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation

21 January 2018

1 reference

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Linear polyamine copper chelator tetraethylenepentamine augments long-term ex vivo expansion of cord blood-derived CD34+ cells and increases their engraftment potential in NOD/SCID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability.

21 January 2018

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Ex vivo expansion of cord blood mononuclear cells on mesenchymal stem cells.

21 January 2018

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Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment.

21 January 2018

1 reference

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Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes

21 January 2018

1 reference

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Intra-bone marrow injection of bone marrow and cord blood cells: an alternative way of transplantation associated with a higher seeding efficiency.

21 January 2018

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A ROSy future for metabolic regulation of HSC division.

21 January 2018

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Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/stromal cell-derived factor-1 alpha-mediated chemotaxis of human cord blood CD34+ progenitor cells

21 January 2018

1 reference

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Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25(High) forkhead box P3+ regulatory T cells.

21 January 2018

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Transplantation of highly purified peripheral blood CD34+ cells from HLA-mismatched parental donors in 14 children: evaluation of early monitoring of engraftment.

21 January 2018

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Protection against lethal Aspergillus fumigatus infection in mice by allogeneic myeloid progenitors is not major histocompatibility complex restricted.

21 January 2018

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Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation

21 January 2018

1 reference

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One-unit versus two-unit cord-blood transplantation for hematologic cancers

21 January 2018

1 reference

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Regulation of Human Mesenchymal Stem Cell Functions by an Autocrine Loop Involving NAD+ Release and P2Y11-Mediated Signaling

21 January 2018

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T cell depletion utilizing CD34+ stem cell selection and CD3+ addback from unrelated adult donors in paediatric allogeneic stem cell transplantation recipients

21 January 2018

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Cytokine-induced selective expansion and maturation of erythroid versus myeloid progenitors from purified cord blood precursor cells.

21 January 2018

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Hematologic, immunologic reconstitution, and outcome of 342 autologous peripheral blood stem cell transplantations after cryopreservation in a -80°C mechanical freezer and preserved less than 6 months

28 November 2018

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Higher mortality after allogeneic peripheral-blood transplantation compared with bone marrow in children and adolescents: the Histocompatibility and Alternate Stem Cell Source Working Committee of the International Bone Marrow Transplant Registry

31 March 2020

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Outcomes among 562 recipients of placental-blood transplants from unrelated donors

31 March 2020

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The generation of colony-forming cells (CFC) and the expansion of hematopoiesis in cultures of human cord blood cells is dependent on the presence of stem cell factor (SCF)

31 March 2020

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Ex vivo manipulation of hematopoietic stem and progenitor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Transplantation of ex vivo expanded cord blood

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Creation of a double chimera after the transplantation of umbilical-cord blood from two partially matched unrelated donors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Double umbilical cord blood transplantation: a study of early engraftment kinetics in leukocyte subsets using HLA-specific monoclonal antibodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Comparison of mesenchymal stem cells obtained from different human tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Engraftment of syngeneic bone marrow is not more efficient after intrafemoral transplantation than after traditional intravenous administration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

CD26 inhibition on CD34+ or lineage- human umbilical cord blood donor hematopoietic stem cells/hematopoietic progenitor cells improves long-term engraftment into NOD/SCID/Beta2null immunodeficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Modulation of hematopoietic stem cell homing and engraftment by CD26

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Homing efficiency, cell cycle kinetics, and survival of quiescent and cycling human CD34(+) cells transplanted into conditioned NOD/SCID recipients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Transplantation of highly purified peripheral-blood CD34+ progenitor cells from related and unrelated donors in children with nonmalignant diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCLINONC.2014.215

Engraftment and survival after unrelated-donor bone marrow transplantation: a report from the national marrow donor program

31 March 2020

1 reference

https://pubmed.ncbi.nlm.nih.gov/25511187

12 December 2020

In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: stromal cell-derived factor-1, steel factor, and the bone marrow environment

1 reference

https://pubmed.ncbi.nlm.nih.gov/25511187

12 December 2020

Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/25511187

12 December 2020

Expansion of cord blood progenitors and use for hemopoietic reconstitution

1 reference

https://pubmed.ncbi.nlm.nih.gov/25511187

12 December 2020