Rab27a and Rab27b control different steps of the exosome secretion pathway (Q24336455)

Exophilin 5

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Unc-13 homolog D

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RAB2B, member RAS oncogene family

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Synaptotagmin like 4

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RAB27A, member RAS oncogene family

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RAB9A, member RAS oncogene family

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RAB27B, member RAS oncogene family

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multivesicular body sorting pathway

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author

Graça Raposo

5

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Nir Hacohen

13

Nir Hacohen

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Matías Ostrowski

Matias Ostrowski

1

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Catarina Moita

Catarina F Moita

7

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Nuno Carmo

Nuno B Carmo

2

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Kristine Schauer

Kristine Schauer

8

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Philippe Benaroch

Philippe Benaroch

12

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Alistair N Hume

Alistair N Hume

9

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Luís F. Moita

Luis F Moita

19

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Miguel C. Seabra

Miguel C Seabra

16

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Sebastian Amigorena

Sebastian Amigorena

18

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Mitsunori Fukuda

Mitsunori Fukuda

14

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Clotilde Théry

20

Clotilde Thery

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Ariel Savina

6

Ariel Savina

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author name string

Sophie Krumeich

3

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Isabelle Fanget

4

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Rui P Freitas

10

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Bruno Goud

11

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Claire Desnos

15

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François Darchen

B lymphocytes secrete antigen-presenting vesicles

17

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language of work or name

English

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publication date

January 2010

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published in

Nature Cell Biology

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volume

12

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issue

1

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page(s)

19-30; sup pp 1-13

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cites work

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Human VPS34 is required for internal vesicle formation within multivesicular endosomes

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Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane

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Rab proteins as membrane organizers

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Chromosomal mapping, gene structure and characterization of the human and murine RAB27B gene

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Evolution of the Rab family of small GTP-binding proteins

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Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis

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The small GTPase Rab27B regulates amylase release from rat parotid acinar cells

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A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport

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Constitutive GDP/GTP exchange and secretion-dependent GTP hydrolysis activity for Rab27 in platelets

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HIV-1 Nef impairs MHC class II antigen presentation and surface expression

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Rab27a regulates the peripheral distribution of melanosomes in melanocytes

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Exosomes: composition, biogenesis and function

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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

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Visualization and quantification of vesicle trafficking on a three-dimensional cytoskeleton network in living cells

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12 December 2020

Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection

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12 December 2020

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes

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12 December 2020

Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells

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12 December 2020

Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes

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12 December 2020

Exosomes biological significance: A concise review

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Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome

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Rab27a is required for regulated secretion in cytotoxic T lymphocytes

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12 December 2020

Cells release prions in association with exosomes

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12 December 2020

Isolation and characterization of exosomes from cell culture supernatants and biological fluids

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12 December 2020

Primed Vesicles Can Be Distinguished from Docked Vesicles by Analyzing Their Mobility

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12 December 2020

Novel chromophores and buried charges control color in mFruits

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12 December 2020

Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

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12 December 2020

Tracking single secretory granules in live chromaffin cells by evanescent-field fluorescence microscopy

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12 December 2020

Rab27b regulates mast cell granule dynamics and secretion

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12 December 2020

A journey through the exocytic pathway.

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Tumour-released exosomes and their implications in cancer immunity.

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12 December 2020

Rab27b regulates number and secretion of platelet dense granules

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12 December 2020

Rab GTPases, intracellular traffic and disease.

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12 December 2020

Myosin va mediates docking of secretory granules at the plasma membrane

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12 December 2020

Alzheimer's disease beta-amyloid peptides are released in association with exosomes

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12 December 2020

MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966785

12 December 2020

The exosome pathway in K562 cells is regulated by Rab11.

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https://pubmed.ncbi.nlm.nih.gov/19966785

12 December 2020

Itinerant exosomes: emerging roles in cell and tissue polarity

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12 December 2020

Analysis of transient behavior in complex trajectories: application to secretory vesicle dynamics

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https://pubmed.ncbi.nlm.nih.gov/19966785

12 December 2020

Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles

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https://pubmed.ncbi.nlm.nih.gov/19966785

12 December 2020

Exosomes: endosomal-derived vesicles shipping extracellular messages

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12 December 2020

Rab GTPases and myosin motors in organelle motility

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12 December 2020

Targeting Tumor Antigens to Secreted Membrane Vesicles In vivo Induces Efficient Antitumor Immune Responses

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12 December 2020

Fas ligand is targeted to secretory lysosomes via a proline-rich domain in its cytoplasmic tail.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966785

12 December 2020

Targeting of Rab GTPases to cellular membranes

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https://pubmed.ncbi.nlm.nih.gov/19966785

12 December 2020

Indirect activation of naïve CD4+ T cells by dendritic cell-derived exosomes

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https://pubmed.ncbi.nlm.nih.gov/19966785

12 December 2020

Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/19966785

12 December 2020

Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells

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https://pubmed.ncbi.nlm.nih.gov/19966785

12 December 2020

Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes

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12 December 2020