A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport (Q24295585)

GOA release 2020-03-11

Myosin VA

1 reference

GOA release 2020-03-11

Melanophilin

1 reference

GOA release 2020-03-11

Abul K Tarafder

3

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ORCID Public Data File 2021

Molly Strom

1

object named as

Molly Strom

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author name string

Alistair N Hume

2

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Eleni Barkagianni

4

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Miguel C Seabra

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

12 July 2002

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published in

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volume

277

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issue

28

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page(s)

25423-30

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cites work

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The melanosome: membrane dynamics in black and white

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Visualization of melanosome dynamics within wild-type and dilute melanocytes suggests a paradigm for myosin V function In vivo

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Of yeast, mice, and men. Rab proteins and organelle transport

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A mutation in Rab27a causes the vesicle transport defects observed in ashen mice

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Rab27a regulates the peripheral distribution of melanosomes in melanocytes

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Novel myosin heavy chain encoded by murine dilute coat colour locus

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Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice

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The leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytes

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Melanophilin, the product of the leaden locus, is required for targeting of myosin-Va to melanosomes

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Rab27a is required for regulated secretion in cytotoxic T lymphocytes

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Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice

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The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain

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Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport

21 January 2018

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Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis

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inferred from DOI database lookup

7 January 2021

based on heuristic

Nucleotide dependence of Rab geranylgeranylation. Rab escort protein interacts preferentially with GDP-bound Rab.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202574200

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M202574200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

11980908

1 reference

Consolidated OpenCitations Corpus – April 2017