DRUG NAME CLASSIFICATION INDICATION SIDE EFFECTS NURSING RESPONSIBILITIES

Generic Name • Check for signs of a MI or stroke

clopidogrel Pregnancy category B Use to reduce the risk of stroke, MI, Excessive tiredness, headache, during
vascular death, peripheral arterial dizziness, nausea, vomiting, therapy
Drug Class: disease in stomach pain, diarrhea, nosebleed • Examine for purpura thrombotic
Platelet aggregation inhibitor high-risk patients, acute coronary or thrombocytic;
syndrome, thrombocytopenia, neurolytic
transient ischemic attack (TIA), anemia, and fever
unstable angina • If a patient is receiving long-term
therapy, keep an eye on their liver
Available Forms function tests, including AST, ALT,
Tabs 75, 300 mg bilirubin, and creatinine.
(4 months or longer)
Mode of Action: Contraindication: Adverse Reaction • Keep an eye on blood tests like
Inhibits first and second phases Hypersensitivity, active bleeding CNS: Headache, dizziness, CBC, Hct, Hgb,
of ADP-induced effects in platelet depression, syncope, hyperesthesia, protime, cholesterol in long-term
aggregation Precautions: neuralgia, confusion, patients
Dosages Pregnancy B, breastfeeding, hallucinations treatment; neutropenia and
75 mg tab children, past liver disease, CV: Edema, hypertension, chest thrombocytopenia may
increased bleeding risk, pain transpire
neutropenia, agranulocytosis, renal GI: Nausea, vomiting, diarrhea, GI Inform the patient that while
disease, Asian/Black/Caucasian discomfort, receiving treatment, blood work
patients GI bleeding, pancreatitis, hepatic will be required.
failure Encourage the patient to report any
GU: Glomerulonephritis unexpected bleeding.
HEMA: Epistaxis, purpura, bleeding inform the prescriber that stopping
(major/minor from any site), could take longer
neutropenia, aplastic anemia, bleeding
agranulocytosis, thrombotic • Instruct the patient to take
thrombocytopenic purpura without considering food.
INTEG: Rash, pruritus • Warn the patient to report any
MISC: UTI, hypercholesterolemia, skin
chest pain, Fatigue, intracranial fever, chills, rashes, and
hemorrhage, toxic epidermal subcutaneous bleeding
necrolysis, Stevens-Johnson sore throat
syndrome, flu-like syndrome, • Instruct the patient to inform all
anaphylaxis medical professionals
MS: Arthralgia, back pain the usage of clopidogrel; may be
RESP: Upper respiratory tract held for five
infection, dyspnea, rhinitis, days prior to the procedure
 bronchitis, cough, bronchospasm

DRUG NAME CLASSIFICATION INDICATION SIDE EFFECTS NURSING RESPONSIBILITIES

Generic Name  Administer to patient
aspirin Pregnancy category D (3rd Use for mild to moderate riRinging in your ears, confusion, crushed or whole;
trimester) pain or fever including hallucinations, rapid breathing, chewable tab should be
rheumatoid arthritis, seizure (convulsions); severe chewed
Drug Class: osteoarthritis, nausea, vomiting, or stomach pain;  Give with food or milk to
Nonopioid analgesic thromboembolic disorders, bloody or tarry stools, coughing up decrease gastric
transient ischemic attacks, blood or vomit that looks like coffee symptoms; separate by 2
rheumatic fever, post-MI, grounds; fever lasting longer than 3 hr of enteric product;
prophylaxis of MI, ischemic stroke, days; or swelling, or pain lasting absorption may be slowed
Available Forms angina; acute MI longer than 10 days.  Give antacids 1-2 hr after
Tabs 81, 325, 500, 650, enteric products
800 mg; chewable tabs 81 mg; supp  Give with 8 oz of water
300, 600, mg; gum 227 mg; enteric Mode of Action: and have patient sit
coated tabs 81, 325, 500, 975 mg; Blocks pain impulses in Contraindication: upright for 30 min after
ext rel 800 mg; del rel tabs 325, 500 CNS, Pregnancy D (3rd trimester), dose; discard tabs if
mg; supp 300, 600 mg reduces inflammation by breastfeeding, children ,12 yr,
vinegar-like smell is
inhibition of prostaglandin children with flulike symptoms,
present; avoid if allergic
synthesis; antipyretic action results hypersensitivity to salicylates,
to tartrazine
from vasodilatation of peripheral tartrazine (FDC yellow dye #5), GI Adverse Reaction
 Give ½ hr before planned
vessels; decreases platelet bleeding, bleeding disorders, vit K CNS: Stimulation, drowsiness,
exercise
Dosages aggregation deficiency, peptic ulcer, acute dizziness, confusion, seizures,
80 mg tab bronchospasm, agranulocytosis, headache, flushing, hallucinations,
 Place suppository in
increased intracranial pressure, coma refrigerator for at least 30
intracranial bleeding, nasal CV: Rapid pulse, pulmonary min before removing
polyps, urticaria edema wrapper
Precautions: EENT: Tinnitus, hearing loss 
Abrupt discontinuation, ENDO: Hypoglycemia,
acetaminophen/NSAIDs hyponatremia, hypokalemia
hypersensitivity, acid/base GI: Nausea, vomiting, GI bleeding,
imbalance, alcoholism, ascites, diarrhea, heartburn, anorexia,
asthma, bone marrow suppression, hepatitis, GI ulcer
geriatric patients, dehydration, HEMA: Thrombocytopenia,
G6PD deficiency, gout, heart failure, agranulocytosis, leukopenia,
anemia, renal/hepatic disease, neutropenia, haemolytic anemia,
pre/postoperatively, gastritis, increased PT, PTT, bleeding time
pregnancy C 1st trimeste INTEG: Rash, urticaria, bruising
RESP: Wheezing, hyperpnea,
bronchospasm
SYST: Reye’s syndrome (children),
anaphylaxis, laryngeal edema
Pharmacokinetic