Search Results (10,447)

Multiple cause data refer to all conditions reported on death certificates. Compared to the single underlying cause of death, these data provide additional information concerning the presence of comorbidities and complications leading to death. The objective of the study is to use a novel multiple cause approach for identifying comorbidities and complications of COVID-19. We analysed certificates referring to deaths that occurred in Italy in 2020–2021. With a double step chi squared test, we identified the conditions associated with COVID-19 and whether such conditions were reported as ‘cause of’ (comorbidities) or ‘due to’ (complications) COVID-19. For comparison, we adopted the same procedure for influenza deaths that occurred in Italy in 2016–2019. Pneumonia, respiratory failure and adult respiratory distress syndrome are the most frequent complications of COVID-19 and are also associated with it. These diseases have the same role for influenza, nevertheless this latter is strongly associated also with heart failure reported as a complication. Comorbidities are similar for COVID-19 and influenza: diabetes mellitus, chronic obstructive pulmonary disease (COPD) and obesity are the most frequent, with obesity much more frequent in COVID-19 cases. Hypertension is strongly associated with COVID-19 and is more frequent than in influenza cases. This approach is also suitable for other target diseases. Full article

Reducing inequality within and between countries and enhancing social welfare are important components of the United Nations’ sustainable development goals. Based on the experience of developed countries or regions, the digital economy and fiscal policy are effective ways of promoting inclusive regional economic growth. Fully considering the completeness and availability of the data, we select the data of China’s less developed regions from 2001 to 2011 for empirical testing. This study empirically examined the effect of the digital economy on regional sustainable development and the underlying mechanism, taking an analysis of the regulatory effect of fiscal policy into account. The results show the following: (1) The digital economy and regional sustainable development exhibit an inverted “U” curve relationship. In the early stage of development, relying on its own economies of scale, the digital economy releases the “digital dividend”, positively affecting the sustainable development of the regional economy; in the later stage, the “digital divide” has a positive impact on the development of the regional economy. The inhibitory effect of the “digital divide” is greater than the enhancement effect of the “digital dividend”, negatively affecting the sustainable development of regional economies. (2) There is regional heterogeneity in the mechanism of the effect of the digital economy on regional sustainable development. The digital economy affects the level of regional sustainable development through the two paths of “comprehensive prosperity” and “holistic well-being”. For the samples in the eastern and western regions, the digital economy plays the role of promoting and then inhibiting, while for the samples in the central region, it plays the role of inhibiting and then promoting. (3) Fiscal policy negatively regulates the effect of the digital economy on regional sustainable development, but the regulatory effect is not significant. Full article

The end-of-life (i.e., on-farm euthanasia and culling, including fitness for transport to slaughter) of a dairy cow or calf is preceded by a series of decisions often influenced by many complex factors. The aim of this study was to utilize the opinions of experts with roles in the dairy supply chain to identify factors that influence end-of-life decision-making for dairy cattle. Twenty experts serving in supporting roles in the dairy supply chain participated in a survey containing 17 open-ended questions. Of the participants, 55% (n = 11) identified as veterinarians and the remaining 45% (n = 9) participated in other segments of the dairy supply chain. Twelve themes were identified in the qualitative analysis of survey responses. The themes included: Training and Resources, Cattle Health Management, Decision-Making Criteria, Company Culture, Personal Beliefs, Human Well-Being, Animal Welfare, Economics, Guidelines and Inspections, Consumer Perceptions, Supply Chain Considerations, and Communication. Experts indicated that training programs should address euthanasia or fitness-for-transport criteria, the knowledge of common health conditions, and information about what happens to cattle after leaving the dairy. Additional influencing factors included personal beliefs, economics, company culture, and supply chain considerations. Full article

IMTA is one of the most innovative and sustainable farming systems, exhibiting the best technique available in rearing aquatic organisms belonging to different positions along the trophic levels. In the literature and in legislation, the environmental benefits of IMTA protocols have been extensively recognized, mainly for its capability to reduce the ecological footprint of intensive aquaculture systems and concretely address the Sustainable Development Goal no. 14 (SDG 14). However, lesser attention is given to the assessments of its role in enhancing the zootechnical performance, animal welfare, and flesh quality of the species involved. To the best of our knowledge, this is the first review that aims to offer a systematic analysis of the existing literature on the main commercial motivations that could draw the attention of stakeholders, including consumers and fish farmers, towards a greater social acceptability and implementation of the IMTA system on a large scale. The findings suggest that, beyond its environmental advantages, IMTA systems can positively influence the productivity, growth, survival, feed efficiency, and animal health and welfare (AH&W), as well as the nutritional quality of the harvested species, thus offering significant economic and market value both in terms of Environmental, Societal and Governance (ESG) parameters and One Health. Full article

Leptospirosis and hantavirus syndrome are two major rodent-borne diseases in Taiwan. Rocahepevirus ratii (RHEV), a virus closely related to hepatitis E virus (HEV, Paslahepevirus balayani), is emerging and has been reported to cause hepatitis in humans. We employed wastewater-based epidemiology to actively monitor rodent-borne pathogens, and the correlations with human cases were evaluated. Wastewater was collected using grab sampling at 11 sites along a sewer system including influents and effluents at a wastewater treatment plant in Tamsui, New Taipei City, Taiwan, monthly during June 2023 to May 2024. The presence of pathogens was examined by reverse transcription-polymerase chain reaction (RT-PCR). The result showed an overall positivity rate of 38.2% (50/131). Leptospira was detected most often (48/131, 36.6%), and RHEV and hantaviruses were found once each during the study period. Sequencing identified Leptospira interrogans close to isolates from rodents and human cases, while sequences of hantavirus and RHEV were most similar to isolates from rodents. No significant correlation was found with human cases or positive samples for rodent DNA. Here, we present an example of a One Health approach applying wastewater to environmental surveillance for the early detection and prevention of emerging diseases. Full article

In modern society, individuals spend an increasing amount of time indoors, emphasizing the importance of understanding the health impacts of indoor environments. This study focused on measuring indoor air quality to identify vulnerable populations and observe the effects of residential environment improvements on air quality. Targeting low-income families and elderly households, known for their heightened vulnerability to environmental health risks, the study involved direct visits to 2328 low-income households across 16 cities and provinces in South Korea from 2021 to 2022. Indoor air quality parameters, including PM_2.5, PM₁₀, total volatile organic compounds (TVOC), formaldehyde (HCHO), and airborne mold, were measured. Among these households, 300 with critically compromised living conditions received support for wallpaper and paneling replacement. Comparative measurements before and after the renovations revealed that single-person households had higher levels of PM_2.5 and TVOC compared with households with four or more members. Additionally, households with elevated concentrations of airborne mold also exhibited higher levels of PM_2.5 and PM₁₀. Importantly, households that received environmental improvements showed a significant reduction in airborne mold concentration by approximately 50% or more. This study underscores the importance of indoor environmental health and provides valuable evidence supporting policies focused on health promotion and residential welfare improvements for vulnerable populations. The research is distinguished by its comprehensive nature, involving direct measurements from nearly 2000 households nationwide, rather than relying solely on secondary data. Full article

This study analyzes and investigates how financial factors, namely, derivatives, debt shifting, and transfer pricing, influence tax avoidance, with financial distress as an interaction variable, within the framework of stakeholder theory and positive accounting theory. Adding more uniqueness, this study injected the Maqasid Syariah elements into the framework. Conventional banks and non-bank institutions listed on the Indonesia Stock Exchange (IDX) between 2017 and 2022 were selected, comprising 414 final company-year observations. The study utilized E-Views software for data processing. The findings indicate that debt shifting negatively impacts tax avoidance, while derivatives have no significant influence. Transfer pricing positively impacts tax avoidance. Financial distress does not moderate the relationship between these financial practices and tax avoidance. From an Islamic perspective, practices such as transfer pricing and debt shifting, when used to avoid tax, contradict the principles of Maqasid Syariah, which emphasize fairness, wealth distribution, and societal welfare. Full article

Background and Objectives: We analyzed the changes in obesity, glucose metabolism, and body composition over a 3-year period in Japanese patients with obesity following laparoscopic sleeve gastrectomy (LSG). Methods: Body weight, parameters related to diabetes such as glycated hemoglobin (HbA1c), and electrical impedance analysis were used to assess body composition in forty-eight Japanese patients with obesity before surgery and 6 months, 1 year, 2 years, and 3 years after LSG. Results: At 6 months, 1, 2, and 3 years post-LSG, there were significant reductions in body weight, body mass index, blood pressure, fasting plasma glucose, triglyceride, and HbA1c levels. Six months after LSG, fat mass (FM), muscle mass (MM), and %FM all showed a decrease compared to pre-treatment values (all p < 0.05). FM and %FM remained in a decreased state until 3 years had passed. In contrast, %MM increased at 6 months post-LSG and was maintained up to 3 years post-LSG (all p < 0.05). Furthermore, changes in FM and %FM were associated with changes in body weight and A1C. In contrast, change in %MM exhibited a negative correlation with body weight and A1C following LSG. Finally, multivariate regression analyses demonstrated that alterations in FM were independent factors affecting body weight in patients with obesity 3 years after LSG. Conclusions: We observed improvements in FM, fasting plasma glucose, and HbA1c levels over a 3-year period in Japanese patients after LSG. The reduction in FM and maintenance of %MM after LSG were suggested as possible links between the effects of LSG on obesity and diabetes over 3 years. Full article

Background/Objectives: The increased use of social media in Mexico has given rise to the “fear of missing out” (FoMO) phenomenon, especially among adolescents. This study aimed to measure the extent of FoMO among junior high school students in the metropolitan area of Guadalajara, Mexico, during the COVID-19 pandemic. Additionally, this study explored the association between FoMO levels and demographic characteristics, as well as the type and frequency of social media use. Methods: A cross-sectional survey was conducted from November 2021 to January 2022 in four junior high schools. A total of 1264 students (656 females and 608 males) aged 11–16 years completed the Fear of Missing Out Scale, adapted to the Mexican context. Data on demographics, social media usage, and school shifts were collected. Statistical analyses were performed using t-tests, ANOVA, and correlation coefficients. Results: The mean FoMO score was 1.79 ± 0.64, with higher scores observed in females (p < 0.001) and students attending morning shifts (p = 0.001). Significant associations were found between higher FoMO scores and the use of social media platforms like Instagram, TikTok, and Pinterest (p < 0.001 for each). The most frequently used social media platforms were WhatsApp (1093), TikTok (828), and Instagram (583). Participants who used social media all week exhibited significantly higher FoMO scores than those who used it only on weekends (p < 0.001). Conclusions: FoMO is a significant phenomenon among junior high school students in Guadalajara, Mexico, particularly among females and those who use multiple social media platforms. The findings suggest a need for interventions to manage social media use and mitigate FoMO-related negative health outcomes in this population. Full article

UWB positioning systems offer innovative solutions for precision monitoring dairy cow behaviour and social dynamics, yet their performance in complex commercial barn environments requires thorough validation. This study evaluated the TrackLab 2.13 (Noldus) UWB system in a dairy barn housing 44–49 cows. We assessed stationary tag positioning using ten fixed tags over seven days, proximity detection between eight cows and ten stationary tags, and moving tag positioning using three tags on a stick to simulate cow movement. System performance varied by tag location, with reliability ranging from 4.09% to 96.73% and an overall mean accuracy of 0.126 ± 0.278 m for stationary tags. After the provider updated the software, only 0.62% of measures exceeded the declared accuracy of 0.30 m. Proximity detection between moving cows and stationary tags showed 81.42% accuracy within a 2-m range. While generally meeting specifications, spatial variations in accuracy and reliability were observed, particularly near barn perimeters. These findings highlight UWB technology’s potential for precision livestock farming, welfare assessment, and behaviour research, including social interactions and space use patterns. Results emphasise the need for careful system setup, regular updates, and context-aware data interpretation in commercial settings to maximise benefits in animal welfare monitoring. Full article

The invasive blue crab is challenging the Mediterranean basin, progressively declining local populations. This reflects a lower prey availability and suitability of dietary nutrients (mainly n-3 polyunsaturated fatty acids, PUFA). The present study aimed to challenge blue crab males and females with a feed source low in n-3 PUFA with respect to one showing a proper fatty acid profile and to investigate the responses in terms of growth, welfare, lipid characterization of target tissues, and reproductive status. Blue crabs were divided into three groups as follows: (i) Marine: crabs fed sardinella (Sardinella aurita) fillet for 60 days; (ii) Mix: crabs fed bovine heart for the first 40 days and sardinella fillet for the following 20 days; and (iii) Terrestrial: crabs fed bovine heart for 60 days. The diet did not alter the health status but reflected the fatty acid profile of muscle and ovary of the blue crabs. In each group, males and females showed a proper hepatopancreas structure, with comparable levels of lipid reserves. This properly supported gonad maturation in both sexes. However, males and females from the group fed the terrestrial diet were characterized by reduced body weight, revealing that blue crabs prioritize reproductive investment rather than growth by directing crucial nutrients to reproductive organs when a suboptimal diet is available. Full article

Background/Objectives: Cancer incidence in young adults or those aged 15–49 years old has increased during the past decade. Knowledge about the risk factors for cancer-related deaths in young adults is limited, particularly in low- and middle-income countries (LMICs). Methods: This analysis was based on the Hanoi Prospective Cohort Study, an ongoing study of 39,401 participants aged 15 or older in Northern Vietnam in the 2007–2019 period. A Cox proportional hazard regression model was used to calculate the hazard ratio (HR) and 95% confidence intervals (95% CIs) for the association between potential factors and the risk of cancer-related deaths. Results: With a median follow-up of 11.01 years, we identified 164 deaths in young adults out of 554 total deaths. Overall, family history of cancer (HR = 7.34; 95% CI: 3.30–16.36), drinking alcohol (HR = 1.82; 95% CI: 1.18–2.81), and smoking (HR = 2.22; 95% CI: 1.36–3.63) were found to be risk factors, while drinking coffee was found to be a protective factor (HR = 0.49; 95% CI: 0.24–1.00) for cancer-related deaths in young adults. Young male adults were found to be at a higher risk due to excessive cigarette smoking (HR = 1.91; 95% CI: 1.00–3.68) and alcohol consumption (HR = 2.15; 95% CI: 1.32–3.53) than those aged 50 years and older (HR = 1.36 and 95% CI: 0.96–1.93 and 1.27 and 95% CI: 0.97–1.67, respectively). The risk of death from cancer in women compared with men in the young population was twice as high as that in the older population (HR = 1.18 and 95% CI: 0.72–1.94 vs. 0.47 and 95% CI: 0.35–0.63, respectively). Conclusions: Our data suggest that the young Vietnamese population is vulnerable to the risk of cancer-related deaths and that cancer in women will increase rapidly in the future. Full article

Daily behavioral analysis of group-housed pigs provides critical insights into early warning systems for pig health issues and animal welfare in smart pig farming. In this study, our main objective was to develop an automated method for monitoring and analyzing the behavior of group-reared pigs to detect health problems and improve animal welfare promptly. We have developed the method named Pig-ByteTrack. Our approach addresses target detection, Multi-Object Tracking (MOT), and behavioral time computation for each pig. The YOLOX-X detection model is employed for pig detection and behavior recognition, followed by Pig-ByteTrack for tracking behavioral information. In 1 min videos, the Pig-ByteTrack algorithm achieved Higher Order Tracking Accuracy (HOTA) of 72.9%, Multi-Object Tracking Accuracy (MOTA) of 91.7%, identification F1 Score (IDF1) of 89.0%, and ID switches (IDs) of 41. Compared with ByteTrack and TransTrack, the Pig-ByteTrack achieved significant improvements in HOTA, IDF1, MOTA, and IDs. In 10 min videos, the Pig-ByteTrack achieved the results with 59.3% of HOTA, 89.6% of MOTA, 53.0% of IDF1, and 198 of IDs, respectively. Experiments on video datasets demonstrate the method’s efficacy in behavior recognition and tracking, offering technical support for health and welfare monitoring of pig herds. Full article

Subacute rumen acidosis (SARA) is a significant concern in dairy cattle fed grain-rich diets. To elucidate the underlying pathophysiological mechanisms, ruminal papilla biopsies are often used. This study aimed to assess how the sampling site along the ruminal papilla influences gene expression profiles in rumen epithelium during SARA. Rumen biopsies from five ruminal-cannulated non-lactating Holstein cows were collected during feeding of a forage diet (FD) and seven (wk1) and 21 days (wk3) after transition to high-grain (HG) feeding. Gene expression in apical (AP), basal (BP), and total length (TP) papillae were compared using RT-qPCR. Significant diet-induced effects were observed in AP for DSG1 (wk3, p = 0.0317), ZO1 (wk1 and wk3, p = 0.0159), GLUT3 (wk3, p = 0.0159), TLR4 (wk3, p = 0.0635), and NFKB (wk1, p = 0.0159), but hardly in BP or TP. Within wk1, TP showed higher transcript levels of ZO1 and TLR4 (p = 0.0079) and SGLT1 (p = 0.0317) compared to AP and BP independently from diet effects. These findings suggest that the apical parts of rumen papillae biopsies are most suitable for gene expression analyses to investigate diet-induced effects on rumen physiology and underscore the importance of considering the sampling site for accurate gene expression studies in rumen epithelium during SARA, providing valuable insights for future research and diagnostic approaches in managing rumen health in dairy cattle. Full article

Lameness, also attributed to musculoskeletal disorders of the back, is a major issue in dairy cow farming, affecting both animal welfare and economics. Chiropractic techniques are well studied in humans and horses for the treatment of musculoskeletal disorders. The anatomy of the bovine spine differs significantly from that of horses, but the knowledge of the animal’s specific anatomy is crucial for chiropractic treatment. This report explores how chiropractic methods could be adapted to cattle, considering their unique anatomy, and potentially integrated into standard veterinary care. Five case reports and an example of measuring the alignment of the facet joints in the spine are presented and discussed. Chiropractic treatments showed success in alleviating lameness and spinal issues in dairy cows, particularly when combined with other interventions. However, the role of chiropractic treatment in cattle as a complementary therapy needs further research. Full article